Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   I6L86_RS03410 Genome accession   NZ_CP077259
Coordinates   747117..748442 (-) Length   441 a.a.
NCBI ID   WP_020902616.1    Uniprot ID   -
Organism   Streptococcus mitis strain FDAARGOS 1456     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 742117..753442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L86_RS03385 (I6L86_03385) - 742813..745455 (-) 2643 WP_000472064.1 YhgE/Pip domain-containing protein -
  I6L86_RS03390 (I6L86_03390) - 745583..746125 (+) 543 WP_001158274.1 TetR/AcrR family transcriptional regulator -
  I6L86_RS03405 (I6L86_03405) comE 746368..747120 (-) 753 WP_000866073.1 competence system response regulator transcription factor ComE Regulator
  I6L86_RS03410 (I6L86_03410) comD 747117..748442 (-) 1326 WP_020902616.1 competence system sensor histidine kinase ComD Regulator
  I6L86_RS03415 (I6L86_03415) comC 748455..748577 (-) 123 WP_004238992.1 competence-stimulating peptide ComC Regulator
  I6L86_RS03425 (I6L86_03425) rlmH 748860..749339 (-) 480 WP_000695934.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6L86_RS03430 (I6L86_03430) htrA 749522..750703 (+) 1182 WP_000681587.1 S1C family serine protease Regulator
  I6L86_RS03435 (I6L86_03435) spo0J 750761..751519 (+) 759 WP_000410370.1 ParB/RepB/Spo0J family partition protein Regulator
  I6L86_RS03440 (I6L86_03440) dnaA 751732..753093 (+) 1362 WP_000660620.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51152.92 Da        Isoelectric Point: 7.5225

>NTDB_id=580359 I6L86_RS03410 WP_020902616.1 747117..748442(-) (comD) [Streptococcus mitis strain FDAARGOS 1456]
MDFLAVLVVILHIFIISKSYYLICKNKINIKELCFFGGYTFLVESVFELSFYFIYLDGLGIEKFLFPLVLYSYFRFIKKY
EKYRGVFLSLLLSLLYNSTHTFLSVTLSSIIGDDTALQYHSLFFLVVVALTYVVIVTIIRYFHLELNYFDKDYLYPFLKK
VFFALLLLHVVSFISDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKEKMEKEIALKQKKFEQKHLQNYTDEIVGLY
NEIRGFRHDYAGMLVSMQMAIDSGDLQEIDRVYNEVLVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEF
TLEVKDKITKLPIELLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFALGFSTKGR
NRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=580359 I6L86_RS03410 WP_020902616.1 747117..748442(-) (comD) [Streptococcus mitis strain FDAARGOS 1456]
ATGGATTTTCTTGCAGTATTAGTTGTGATATTACATATTTTTATTATTAGTAAAAGTTACTATTTAATATGTAAAAATAA
AATAAATATAAAAGAACTATGCTTTTTTGGTGGTTATACATTCCTAGTAGAATCAGTATTTGAACTTTCCTTTTATTTTA
TATACTTAGATGGATTAGGAATTGAAAAATTTTTATTTCCTTTGGTATTATATTCATATTTTAGATTTATTAAAAAGTAT
GAGAAGTATAGAGGAGTATTCTTAAGTTTACTACTATCCCTTTTATATAATAGCACTCATACCTTTCTATCCGTAACTTT
ATCCTCTATAATAGGAGATGATACTGCCCTACAATATCATAGTCTATTCTTTTTAGTTGTAGTGGCGTTGACTTATGTTG
TTATCGTAACAATCATTCGTTATTTCCATTTGGAACTAAACTATTTTGACAAAGATTATCTCTATCCTTTCTTGAAAAAA
GTCTTTTTTGCTTTACTACTTCTACATGTTGTATCTTTCATTTCAGATATGGTAAGTACGATTAAACATTTGAATAGTTT
TGGAAGTATTTTATCATCTATTGTCTTTATCTCTTTACTTTTGACCTTTTTTGCAATGAATTCGCATAAAGAAAAAATGG
AGAAAGAGATTGCTTTGAAGCAGAAGAAATTTGAACAGAAACATTTACAGAATTATACAGATGAAATTGTCGGACTGTAT
AATGAAATCCGTGGTTTTCGACATGACTATGCCGGGATGCTTGTCAGCATGCAGATGGCAATTGATAGTGGTGATTTACA
GGAAATTGACAGAGTTTACAATGAAGTTTTGGTCAAAGCAAATCACAAACTGCGTTCAGATAAGTATACTTACTTTGACT
TGAACAACATAGAAGATTCAGCTTTACGAAGTTTGGTTGCTCAGTCAATTGTCTATGCTCGAAATAATGGTGTAGAGTTT
ACACTGGAAGTAAAAGATAAGATTACCAAGCTCCCAATTGAACTATTGGATTTGGTTCGTATCATGAGTGTTTTATTGAA
CAATGCTGTAGAAGGATCAGCTGATAGCTATAAAAAACAAATGGAAGTAGCAGTTATTAAGATGGAAACCGAAACAGTTA
TTGTGATTCAGAATTCATGTAAAATGACGATGACTCCTTCAGGAGATCTATTTGCCTTAGGATTCTCCACTAAGGGAAGA
AATCGCGGAGTAGGCTTAAATAATGTGAAAGAACTACTAGATAAATACAACAATATTATTTTAGAAACAGAGATGGAAGG
CAGTACATTTAGACAAATTATTAGGTTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis NCTC 12261

100

100

1
  comD/comD2 Streptococcus pneumoniae TIGR4

86.621

100

0.866
  comD/comD1 Streptococcus pneumoniae D39

86.168

100

0.862
  comD/comD1 Streptococcus pneumoniae R6

86.168

100

0.862
  comD/comD1 Streptococcus pneumoniae Rx1

86.168

100

0.862
  comD Streptococcus mitis SK321

85.261

100

0.853
  comD/comD2 Streptococcus gordonii strain NCTC7865

47.044

88.209

0.415
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

48.128

84.807

0.408