Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I6L85_RS02380 Genome accession   NZ_CP077248
Coordinates   455894..456622 (+) Length   242 a.a.
NCBI ID   WP_111724049.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS 1455     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 450894..461622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L85_RS02365 (I6L85_02365) - 451065..452630 (-) 1566 WP_111724051.1 ABC transporter substrate-binding protein/permease -
  I6L85_RS02370 (I6L85_02370) - 452844..454835 (+) 1992 WP_269459933.1 DUF2207 domain-containing protein -
  I6L85_RS02375 (I6L85_02375) - 454924..455772 (+) 849 WP_061597407.1 undecaprenyl-diphosphate phosphatase -
  I6L85_RS02380 (I6L85_02380) mecA 455894..456622 (+) 729 WP_111724049.1 adaptor protein MecA Regulator
  I6L85_RS02385 (I6L85_02385) - 456616..457782 (+) 1167 WP_111724048.1 glycosyltransferase family 4 protein -
  I6L85_RS02390 (I6L85_02390) sufC 457869..458639 (+) 771 WP_008809634.1 Fe-S cluster assembly ATPase SufC -
  I6L85_RS02395 (I6L85_02395) sufD 458681..459943 (+) 1263 WP_111724047.1 Fe-S cluster assembly protein SufD -
  I6L85_RS02400 (I6L85_02400) - 459983..461215 (+) 1233 WP_111724046.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28326.99 Da        Isoelectric Point: 4.1819

>NTDB_id=580255 I6L85_RS02380 WP_111724049.1 455894..456622(+) (mecA) [Streptococcus gordonii strain FDAARGOS 1455]
MEVKQISESTIKITIKLEDLEEHGMEMADFLVPQEKTEEFFYTILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKV
DKNLNFEDLADLPDMDELSQMTPDEFLKTLEKNIFEKSRDDIDAVQMLEKAEEEDTSEPEEGQEQDRYIYYILRFSDLKN
LIAFTKTIHYPVDTSELYKMDQHYYLTILVDIEGRPSRYPAWLLAAMREHAEDTDTTRALLQEHGHLLIVTDAVQHLQKV
NC

Nucleotide


Download         Length: 729 bp        

>NTDB_id=580255 I6L85_RS02380 WP_111724049.1 455894..456622(+) (mecA) [Streptococcus gordonii strain FDAARGOS 1455]
ATGGAAGTGAAGCAAATTAGTGAATCAACAATCAAGATCACCATCAAATTAGAAGATCTAGAAGAGCATGGTATGGAAAT
GGCTGATTTTCTGGTTCCTCAAGAAAAGACGGAGGAATTTTTCTATACCATTTTGGACGAACTAGAAATGCCAGAAAGCT
TTTTAGATAGTGGAATGCTGAGTTTTCGGGTGACTCCAAAACCAGACAAATTAGACGTTTTTGTCACAAAATCTAAAGTA
GACAAAAATTTAAATTTTGAAGATTTGGCTGACTTACCTGATATGGACGAACTTTCTCAAATGACTCCGGATGAATTTCT
AAAGACGCTTGAAAAAAACATCTTTGAAAAGAGTCGTGATGATATAGATGCAGTTCAAATGCTGGAAAAAGCGGAAGAGG
AAGATACATCTGAACCAGAGGAAGGGCAAGAACAAGATCGCTATATTTATTATATCTTGCGTTTTTCTGACTTGAAAAAT
CTGATCGCTTTCACCAAGACTATCCACTATCCAGTTGATACATCAGAGCTATACAAAATGGATCAGCACTATTATTTGAC
TATTCTAGTAGATATTGAAGGTCGTCCGAGCCGTTATCCTGCTTGGCTTCTGGCAGCAATGCGTGAACATGCTGAGGATA
CAGATACGACAAGAGCCCTTCTTCAAGAGCACGGTCACTTGTTGATTGTAACAGATGCTGTGCAACATCTTCAAAAGGTA
AACTGCTGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

65.306

100

0.661
  mecA Streptococcus pneumoniae D39

65.306

100

0.661
  mecA Streptococcus pneumoniae R6

65.306

100

0.661
  mecA Streptococcus pneumoniae TIGR4

65.306

100

0.661
  mecA Streptococcus mutans UA159

51.44

100

0.517
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.492
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.488