Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ECBG_RS04510 Genome accession   NC_020995
Coordinates   998595..999899 (-) Length   434 a.a.
NCBI ID   WP_015509239.1    Uniprot ID   A0A200IEL7
Organism   Enterococcus casseliflavus EC20     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 993595..1004899
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECBG_RS04480 (ECBG_00282) - 993598..994632 (+) 1035 WP_015509236.1 hypothetical protein -
  ECBG_RS04485 (ECBG_00283) - 994693..995037 (-) 345 WP_005225425.1 peptidase -
  ECBG_RS04490 (ECBG_00285) pepA 995330..996406 (+) 1077 WP_034870266.1 glutamyl aminopeptidase -
  ECBG_RS04495 (ECBG_00286) - 996540..996860 (+) 321 WP_026008043.1 thioredoxin family protein -
  ECBG_RS04500 (ECBG_00287) - 996873..997334 (+) 462 WP_005225429.1 universal stress protein -
  ECBG_RS04505 (ECBG_00288) ytpR 997912..998526 (+) 615 WP_005225431.1 YtpR family tRNA-binding protein -
  ECBG_RS04510 (ECBG_00289) htrA 998595..999899 (-) 1305 WP_015509239.1 trypsin-like peptidase domain-containing protein Regulator
  ECBG_RS04515 (ECBG_00291) rlmH 1000273..1000752 (+) 480 WP_008379108.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ECBG_RS04520 (ECBG_00292) - 1000796..1001656 (+) 861 WP_015509240.1 hypothetical protein -
  ECBG_RS04525 (ECBG_00293) truA 1001846..1002583 (+) 738 WP_005225435.1 tRNA pseudouridine(38-40) synthase TruA -
  ECBG_RS04530 (ECBG_00294) map 1002626..1003390 (+) 765 WP_015509241.1 type I methionyl aminopeptidase -
  ECBG_RS16760 - 1003621..1003778 (+) 158 Protein_907 type II toxin-antitoxin system prevent-host-death family antitoxin -
  ECBG_RS16555 - 1004577..1004732 (+) 156 WP_157786151.1 hypothetical protein -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 44863.37 Da        Isoelectric Point: 4.0412

>NTDB_id=57810 ECBG_RS04510 WP_015509239.1 998595..999899(-) (htrA) [Enterococcus casseliflavus EC20]
MARKYVTPGKKTSPGLLKRLGIGILGGMVGGLLTFGGLYLAMGSSLTSTPETTTNSGVQDSNGQTQVSNVKLDVTSDVTE
AVEKVQDSVVSIINLQQSQSNDWNSLFGQQGGQSEGDSQSDDDSALEASSEGSGVIYKIDGDDAYVVTNNHVVEGQDGLE
VVLADGTKVKAELVGTDAYTDLAVLKISSEHVKTAATFGDSSALKVGEPAIAIGSPLGSDYANSVTQGIVSSLNRQVTSQ
NESGGTISINAIQTDAAINPGNSGGPLINVDGQVIGINSSKIASTSGSASGVSVEGMGFAIPSNDVVEIINQLEADGKVV
RPALGIQTIDLGSITSQQQEQILKVPSSVTSGVVIYSVNNATPAEQAGLQQYDVITKIDDTEVSTTTDLQSALYKHKVGD
TITVTFYRGDEEKTAEVKLSVDTSINEQSTDSSN

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=57810 ECBG_RS04510 WP_015509239.1 998595..999899(-) (htrA) [Enterococcus casseliflavus EC20]
ATGGCAAGAAAATATGTCACACCAGGCAAGAAAACTTCTCCTGGTTTATTAAAACGATTAGGTATTGGGATTTTAGGCGG
TATGGTCGGCGGTTTATTGACCTTCGGCGGTCTGTATCTGGCAATGGGTTCCTCTTTGACTTCAACACCAGAAACCACGA
CCAACAGCGGGGTCCAAGATTCTAACGGACAAACCCAAGTATCCAATGTAAAACTTGATGTGACTAGCGATGTCACTGAG
GCAGTTGAAAAAGTACAAGATTCTGTCGTTTCCATCATTAATCTACAACAAAGTCAAAGCAACGACTGGAACAGCCTCTT
TGGTCAGCAAGGTGGACAAAGTGAAGGCGATAGCCAAAGCGACGACGACAGTGCTTTAGAAGCTTCTTCTGAAGGGAGTG
GGGTCATCTACAAAATCGATGGCGACGATGCCTATGTCGTAACCAACAACCACGTTGTTGAAGGTCAAGACGGTTTAGAA
GTTGTTTTAGCTGACGGTACGAAAGTCAAAGCTGAATTGGTCGGTACTGACGCTTACACAGACTTAGCTGTATTGAAAAT
CTCTTCAGAGCATGTGAAGACTGCCGCAACATTTGGTGATTCAAGTGCCTTGAAAGTCGGCGAACCAGCCATCGCGATTG
GTTCTCCTCTAGGCTCTGACTACGCAAACTCTGTGACACAAGGGATCGTTTCTTCCTTGAATCGTCAAGTAACAAGCCAA
AACGAATCTGGTGGTACGATCAGCATCAATGCGATCCAAACGGATGCTGCGATCAACCCAGGGAACTCAGGTGGCCCACT
GATCAACGTTGATGGTCAAGTGATTGGGATCAACTCAAGTAAAATCGCCAGCACCTCTGGCTCTGCTTCAGGTGTTAGTG
TCGAAGGGATGGGCTTTGCGATCCCAAGTAACGATGTCGTTGAAATCATCAATCAACTAGAAGCAGACGGCAAAGTGGTT
CGCCCTGCACTAGGGATCCAAACGATCGATTTAGGTTCCATCACATCACAACAACAAGAACAAATCTTGAAAGTTCCTTC
ATCCGTAACTTCTGGCGTTGTGATCTACTCAGTCAACAATGCAACACCAGCAGAACAAGCAGGATTGCAACAATATGACG
TTATCACGAAGATCGATGACACAGAAGTCAGCACAACAACGGATCTGCAATCTGCGTTGTACAAACACAAAGTCGGTGAC
ACGATCACTGTAACCTTCTATCGTGGCGATGAAGAAAAAACGGCAGAAGTAAAACTTTCCGTTGATACGTCGATCAACGA
ACAATCAACAGACAGCAGCAACTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

Peptidase family M50 (Peptidase_M50)

(18-420)

PDZ domain (PDZ_2)

(322-419)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A200IEL7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

56.171

91.475

0.514
  htrA Streptococcus gordonii str. Challis substr. CH1

51.074

96.544

0.493
  htrA Streptococcus mitis NCTC 12261

55.432

82.719

0.459
  htrA Streptococcus pneumoniae TIGR4

57.018

78.802

0.449
  htrA Streptococcus pneumoniae Rx1

57.018

78.802

0.449
  htrA Streptococcus pneumoniae D39

57.018

78.802

0.449
  htrA Streptococcus pneumoniae R6

57.018

78.802

0.449

Multiple sequence alignment