Detailed information NTG0577486

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: KRG72_RS08315
• Genome accession: NZ_CP076703
• Coordinates: 1674020..1676167 (+)
• Length: 715 a.a.
• NCBI ID: WP_258254942.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain S1
• Function: transport of ComC (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1669722..1679034	1674020..1676167	within	0

Gene organization within MGE regions

Location: 1669722..1679034

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KRG72_RS08280 (KRG72_08290)	-	1670027..1671319 (-)	1293	WP_258254929.1	glycosyltransferase family 2 protein	-
KRG72_RS08285 (KRG72_08295)	-	1671322..1671621 (-)	300	WP_157327346.1	DUF3884 family protein	-
KRG72_RS08290 (KRG72_08300)	-	1671647..1671829 (-)	183	WP_157327348.1	hypothetical protein	-
KRG72_RS08295 (KRG72_08305)	-	1671895..1672119 (-)	225	WP_039697856.1	helix-turn-helix domain-containing protein	-
KRG72_RS08300 (KRG72_08310)	-	1672109..1673107 (-)	999	WP_258254932.1	thioredoxin family protein	-
KRG72_RS08305 (KRG72_08315)	-	1673367..1673576 (-)	210	WP_258254933.1	hypothetical protein	-
KRG72_RS08310 (KRG72_08320)	-	1673617..1673781 (-)	165	WP_258254936.1	Blp family class II bacteriocin	-
KRG72_RS08315 (KRG72_08325)	comA/nlmT	1674020..1676167 (+)	2148	WP_258254942.1	peptide cleavage/export ABC transporter	Regulator
KRG72_RS08320 (KRG72_08330)	-	1676177..1677559 (+)	1383	WP_258254944.1	bacteriocin secretion accessory protein	-
KRG72_RS08325 (KRG72_08335)	-	1678104..1678778 (-)	675	WP_258254945.1	CPBP family intramembrane glutamic endopeptidase	-
KRG72_RS08330 (KRG72_08340)	-	1678876..1679034 (-)	159	WP_258254948.1	bacteriocin class II family protein	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80110.26 Da
• Isoelectric Point: 8.6370

>NTDB_id=577486 KRG72_RS08315 WP_258254942.1 1674020..1676167(+) (comA/nlmT) [Streptococcus equinus strain S1]
MRRYKYVSQIDMRDCGVAALASVAKHYGSHFSLAHLRELAKTNKEGTTALGIVEAAKNIGFETRAVKADMALFEMDDIPY
PCIVHVNKQGKLQHYYVIYKAKKDYLIIGDPDPSVGVTKMTKADFAKEWTGVTIFLAPAASYKPHKDKKNGLMSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNQLQSTLGIVSIGLVVTYIMQQIMSFSQQYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNAKLFLITLIALPVYAVII
FAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEETRYRNIDSEFVEYLDKSFTLNKYEAMQASLKQGAQLIL
NVAILWYGSRLVMTGKISVGQLITYNTLLSYFTKPMENIINLQTKLQSAKVANKRLNEVYLVSSEFDNKQVIDNQEFLKG
DLVFDDVSYKYGFGRDTLSHIKLRIKEGEKVSLVGISGSGKTTLAKMMVNFYSPNQGQITLGGYDYKTIDKKVLRQHINY
LPQQSYVFSGSILDNLTLGASDAITQEDIIKACEIAEIRADIEAMPMAYHTELSDGAGLSGGQKQRLAIARALLTKSPVL
ILDEATSGLDVLTEKRVIHNLLALKDKTIIFVAHRLSIAKQTDRVIVLDKGQIIEQGHHEQLMQNPGFYAQLFQE

Nucleotide

• Length: 2148 bp

>NTDB_id=577486 KRG72_RS08315 WP_258254942.1 1674020..1676167(+) (comA/nlmT) [Streptococcus equinus strain S1]
ATGAGGAGATACAAATACGTTAGTCAGATTGATATGCGAGATTGTGGGGTAGCTGCTTTGGCGTCAGTTGCTAAACACTA
CGGCTCACATTTTTCGCTTGCTCACTTAAGGGAACTGGCTAAGACGAATAAAGAAGGAACAACTGCTCTTGGAATCGTCG
AGGCAGCCAAAAATATTGGCTTTGAAACACGCGCTGTAAAAGCTGATATGGCACTTTTTGAGATGGATGATATCCCGTAT
CCTTGCATTGTCCATGTGAATAAGCAAGGAAAACTACAACACTATTATGTCATCTATAAAGCTAAAAAAGATTATCTAAT
CATCGGTGATCCTGACCCAAGTGTGGGAGTCACAAAAATGACTAAAGCAGATTTTGCCAAAGAATGGACAGGGGTTACGA
TCTTTCTAGCTCCTGCAGCTAGCTATAAACCACATAAGGATAAGAAAAATGGCTTGATGAGTTTCTTACCGATTATTTTT
AAGCAAAAAGCACTACTAACATATATAATCCTTGCCAGCCTACTTGTTACCTTGATTAATATTGTCGGCTCTTATTATCT
TCAAGGAATCTTAGACGACTATATTCCCAATCAACTGCAATCCACCCTTGGTATTGTCTCAATCGGCTTGGTCGTAACTT
ACATCATGCAACAGATTATGAGCTTTTCACAACAGTATTTGTTAGTTGTGCTCAGTCAACGTTTGACGATTGATGTCATT
TTATCTTATATTCGTCATATTTTTGAATTGCCTATGTCCTTTTTTGCGACAAGACGAACTGGGGAAGTGATTTCACGCTT
TACCGACGCTAACTCTATCATCGATGCCCTTGCTTCAACAATCTTATCGCTTTTTCTCGATGTGAGTATCCTTTTCATCG
TTGGCAGTGTTTTAATTTTGCAAAATGCGAAACTCTTCTTGATAACCTTAATTGCTTTGCCTGTTTATGCCGTCATTATC
TTTGCTTTTATGAAGCCTTTTGAGCGAATGAATCATGACGTCATGCAAGCTAATTCTATGGTCAGCTCTGCCATTATTGA
AGATATCAACGGGATTGAAACCATTAAATCACTAACTAGCGAGGAGACACGTTATCGCAATATCGATAGTGAATTCGTGG
AATACTTGGATAAAAGTTTCACACTTAATAAATACGAAGCAATGCAAGCCTCACTTAAGCAAGGAGCACAGCTGATTTTA
AATGTGGCTATTCTCTGGTACGGCTCACGTCTCGTTATGACAGGGAAGATTTCTGTTGGGCAGTTGATTACCTACAACAC
CCTTTTATCCTACTTCACAAAACCAATGGAAAACATTATTAACTTGCAAACTAAGTTACAGTCAGCGAAAGTGGCTAACA
AGCGACTTAACGAAGTTTACTTGGTATCTTCTGAATTTGATAACAAGCAAGTGATTGATAATCAAGAGTTTCTCAAAGGT
GACCTTGTCTTTGATGATGTTTCTTATAAATACGGCTTTGGACGCGACACTCTTAGTCACATTAAACTTCGTATCAAAGA
AGGTGAAAAAGTTAGCCTTGTCGGCATCAGTGGTTCTGGTAAAACAACCTTGGCTAAAATGATGGTTAATTTTTACAGTC
CAAATCAAGGGCAAATCACCTTGGGAGGCTACGACTATAAAACTATTGATAAAAAAGTTCTTCGTCAACACATCAACTAC
CTTCCACAACAATCTTATGTCTTTTCTGGAAGTATCCTTGATAATCTCACTTTAGGTGCTTCTGATGCGATTACTCAAGA
AGACATTATCAAAGCCTGTGAAATCGCTGAAATTCGTGCTGACATTGAAGCTATGCCAATGGCTTACCACACTGAATTAT
CAGATGGGGCTGGTTTATCTGGCGGTCAAAAACAACGATTAGCTATTGCCAGAGCACTTCTGACTAAGTCACCCGTCTTA
ATCCTAGATGAAGCAACAAGTGGTCTTGATGTGCTGACCGAAAAACGTGTTATCCACAATTTGTTAGCTTTAAAAGACAA
AACCATTATCTTTGTTGCTCACCGTTTAAGCATTGCCAAGCAAACTGACCGTGTCATCGTCCTAGATAAAGGACAAATTA
TCGAACAAGGTCATCACGAGCAACTCATGCAAAATCCTGGCTTTTACGCTCAGCTATTTCAAGAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (498-647)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

• Peptidase C39 family (Peptidase_C39) (3-140)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	69.425	99.72	0.692
comA	Streptococcus mitis NCTC 12261	66.667	99.021	0.66
comA	Streptococcus pneumoniae Rx1	65.678	99.021	0.65
comA	Streptococcus pneumoniae D39	65.678	99.021	0.65
comA	Streptococcus pneumoniae R6	65.678	99.021	0.65
comA	Streptococcus mitis SK321	65.678	99.021	0.65
comA	Streptococcus pneumoniae TIGR4	65.395	99.021	0.648
comA	Streptococcus gordonii str. Challis substr. CH1	63.904	99.58	0.636