Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   KRG72_RS02360 Genome accession   NZ_CP076703
Coordinates   445990..447879 (+) Length   629 a.a.
NCBI ID   WP_258255706.1    Uniprot ID   -
Organism   Streptococcus equinus strain S1     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 440990..452879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS02345 (KRG72_02345) fmt 442968..443903 (+) 936 WP_074561288.1 methionyl-tRNA formyltransferase -
  KRG72_RS02350 (KRG72_02350) rsmB 443893..445215 (+) 1323 WP_258255704.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KRG72_RS02355 (KRG72_02355) - 445253..445990 (+) 738 WP_074482688.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KRG72_RS02360 (KRG72_02360) stkP/pknB 445990..447879 (+) 1890 WP_258255706.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  KRG72_RS02365 (KRG72_02365) liaF 447977..448672 (+) 696 WP_039695888.1 cell wall-active antibiotics response protein LiaF -
  KRG72_RS02370 (KRG72_02370) - 448669..449694 (+) 1026 WP_258255711.1 sensor histidine kinase -
  KRG72_RS02375 (KRG72_02375) - 449678..450322 (+) 645 WP_006531177.1 response regulator transcription factor -
  KRG72_RS02380 (KRG72_02380) - 450446..451846 (+) 1401 WP_081341909.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  KRG72_RS02385 (KRG72_02385) - 451846..452202 (+) 357 WP_020916316.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 629 a.a.        Molecular weight: 68141.02 Da        Isoelectric Point: 6.7917

>NTDB_id=577450 KRG72_RS02360 WP_258255706.1 445990..447879(+) (stkP/pknB) [Streptococcus equinus strain S1]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSRERKLVFEDTENTKTLPKVTTSTPVPSTTEQLLKKQKAAKVN
REAADNKIAKAKTKKKKSHRMFGTLVKIFFAVVVVAIAIFTYLTLSTPASVNVPDVAGTSLADAKTSLTSAGLKVGDIHK
VASDTVQKGHVIKTDPTAGSSKKEGAKVDIYVSKGTSGFKMKDYTGQNYQEVIKELKDKHGISSDKIDVEWVTGTNYDGG
TIISQTPGKGTKVANEDKITFKVAAIVMPNLIGYTYQDAIAELTALGLSSSHITVFQADATSSTGYSQVKTPSASAVVVA
QDPYFGAAIEGNVKLYFSAGSESQSSEVAPSQSVPESSETSETSESSSSSSSSSSTEESSQTDSSSVEQ

Nucleotide


Download         Length: 1890 bp        

>NTDB_id=577450 KRG72_RS02360 WP_258255706.1 445990..447879(+) (stkP/pknB) [Streptococcus equinus strain S1]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGGATCCTCAAATCTATCGGACGGGGTGGAATGGCAGATGTTTA
TCTTGCCAAAGATCTAATTCTTGATAATGAAGAAGTGGCTATCAAAGTCCTTCGAACTAATTATCAAACAGATCAAATTG
CCGTTGCTCGTTTCCAACGTGAAGCGCGTGCCATGGCAGAGCTAAACCATCCAAATATCGTTTCGATTCGTGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGTTCGGACTTGAAAAAATATATTCAAGACCATGCCCC
GCTTTCTAATAATGAAGTTGTTAGAATCATGGAAGAAGTCTTGTCTGCGATGACTTTGGCTCATCAACAAGGAATTGTTC
ACCGTGATTTGAAACCACAAAATATCTTGTTAACCAAAGACGGAACGGTTAAAGTTACCGACTTTGGTATCGCTGTAGCT
TTTGCAGAAACAAGTTTAACACAGACAAACTCAATGCTTGGTAGTGTGCATTATCTATCGCCTGAACAAGCGCGTGGTTC
AAAGGCCACTGTTCAAAGTGATATCTACGCTATGGGGATTATGTTGTTTGAAATGTTGACTGGTCACATCCCATATGATG
GTGATTCAGCTGTTACAATTGCTCTTCAGCATTTCCAAAAACCACTTCCATCAATCATTGATGAAAATAAAAATGTTCCA
CAAGCTTTGGAAAATGTTGTCATTAAAGCAACTGCAAAACGTTTGAGTGATCGCTACGCCTCAACTTTTGAGATGAGCCG
TGATTTAATGACTGCTCTTTCATATAATCGCAGTCGTGAACGCAAACTTGTCTTTGAAGATACAGAAAATACGAAGACAC
TTCCAAAAGTAACAACTTCAACACCTGTTCCCTCAACTACAGAACAATTGTTGAAAAAACAAAAAGCGGCTAAAGTTAAT
CGTGAAGCTGCGGATAATAAAATTGCAAAAGCGAAAACGAAGAAGAAAAAATCACATCGTATGTTTGGTACTTTAGTGAA
AATTTTCTTTGCGGTCGTAGTAGTTGCAATTGCTATTTTTACTTACTTGACGCTAAGCACACCAGCTTCAGTCAACGTTC
CAGATGTAGCAGGAACAAGTTTAGCAGATGCTAAGACAAGTTTAACTTCAGCTGGACTTAAAGTTGGTGATATTCATAAA
GTAGCTAGTGATACTGTGCAAAAAGGTCATGTTATTAAGACTGACCCAACAGCAGGTTCATCTAAAAAAGAAGGTGCCAA
AGTTGACATTTATGTGTCAAAAGGAACATCAGGCTTTAAGATGAAAGATTATACTGGTCAAAACTATCAAGAAGTTATCA
AAGAACTCAAAGATAAGCACGGTATTTCAAGTGATAAGATTGATGTTGAATGGGTAACAGGTACTAACTATGACGGTGGT
ACTATCATTAGTCAAACACCTGGAAAAGGTACAAAAGTAGCTAATGAAGATAAGATTACTTTCAAGGTTGCAGCAATCGT
TATGCCAAACCTTATTGGTTATACTTATCAAGATGCAATTGCTGAATTGACTGCACTTGGCTTATCAAGCTCACATATTA
CAGTATTCCAAGCAGATGCTACTTCATCAACTGGATACTCTCAAGTCAAAACACCATCTGCCTCTGCAGTTGTTGTGGCA
CAAGATCCTTACTTTGGCGCAGCTATTGAAGGGAATGTGAAACTTTACTTCTCAGCTGGAAGTGAATCTCAGTCTTCAGA
AGTCGCACCATCCCAATCTGTTCCTGAGTCATCTGAGACAAGTGAAACTAGTGAGTCAAGTTCTTCAAGTAGCAGCAGTA
GCAGCACTGAAGAAAGTTCACAAACCGACTCATCATCAGTTGAACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(440-503)

PASTA domain (PASTA)

(507-578)

PASTA domain (PASTA)

(371-434)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

61.182

99.523

0.609
  pknB Streptococcus mutans UA159

66.025

90.779

0.599
  stkP Streptococcus pneumoniae TIGR4

58.757

84.42

0.496
  stkP Streptococcus pneumoniae D39

58.569

84.42

0.494
  stkP Streptococcus pneumoniae R6

58.569

84.42

0.494
  stkP Streptococcus pneumoniae Rx1

58.38

84.42

0.493