Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   MP387_RS08410 Genome accession   NZ_CP094226
Coordinates   1723770..1725719 (-) Length   649 a.a.
NCBI ID   WP_242746288.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1718770..1730719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS08375 (MP387_08375) - 1719044..1719391 (+) 348 WP_007520826.1 TfoX/Sxy family protein -
  MP387_RS08380 (MP387_08380) - 1719659..1720693 (+) 1035 WP_242748062.1 S66 peptidase family protein -
  MP387_RS08385 (MP387_08385) - 1720799..1721062 (+) 264 WP_000166112.1 SemiSWEET family transporter -
  MP387_RS08390 (MP387_08390) - 1721134..1721808 (-) 675 WP_242746281.1 type II CAAX endopeptidase family protein -
  MP387_RS08395 (MP387_08395) - 1721809..1722369 (-) 561 WP_242746283.1 DNA-3-methyladenine glycosylase I -
  MP387_RS08400 (MP387_08400) ruvA 1722379..1722972 (-) 594 WP_242746285.1 Holliday junction branch migration protein RuvA Machinery gene
  MP387_RS08405 (MP387_08405) - 1723132..1723629 (+) 498 WP_242748064.1 helix-turn-helix transcriptional regulator -
  MP387_RS08410 (MP387_08410) hexB 1723770..1725719 (-) 1950 WP_242746288.1 DNA mismatch repair endonuclease MutL Machinery gene
  MP387_RS08415 (MP387_08415) - 1726033..1726473 (+) 441 WP_242746292.1 LytTR family DNA-binding domain-containing protein -
  MP387_RS08420 (MP387_08420) - 1726470..1726928 (+) 459 WP_242746304.1 DUF3021 domain-containing protein -
  MP387_RS08425 (MP387_08425) hexA 1726969..1729503 (-) 2535 WP_242746306.1 DNA mismatch repair protein MutS Machinery gene
  MP387_RS08430 (MP387_08430) argR 1729554..1730000 (-) 447 WP_242746308.1 arginine repressor -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73321.80 Da        Isoelectric Point: 5.6216

>NTDB_id=577262 MP387_RS08410 WP_242746288.1 1723770..1725719(-) (hexB) [Streptococcus oralis strain 1648]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEESGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEAITPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSAKKMIAIENSDLDFEITGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKERELMALVSE
AIAKSLKEQTLIPDALENLAKSTVRNRQKVEQTILPLKENTLYYEKTELSKPSQAEVADHQVELTEEGQDLTLFAKETLD
QLTKPAKLHFAERKPANYDQLDHPELDLASLDKAYDKLEREESSSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLRERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=577262 MP387_RS08410 WP_242746288.1 1723770..1725719(-) (hexB) [Streptococcus oralis strain 1648]
ATGTCTCATATTATTGAATTGCCAGAGGTGCTGGCAAACCAGATCGCGGCAGGGGAGGTTATCGAACGTCCTGCCAGTGT
AGTCAAAGAGTTGGTAGAAAATGCCATTGACGCGGGTTCTAGCCAGATTATCATTGAGATTGAGGAATCAGGTCTAAAGA
AGATTCAAATCACAGATAATGGCCATGGAATTGCCCACGATGAGGTGGAATTGGCCTTGCGTCGTCATGCAACCAGTAAG
ATAAAAAATCAAGCAGACCTCTTTCGGATTCGGACGCTCGGATTTCGAGGTGAAGCCCTGCCCTCTATCGCTTCTGTCAG
TGTTCTGACTCTGTTGACGGCGGTGGATGGTGCGAGTCATGGGACCAAGCTCGTTGCGCGTGGGGGTGAAGTCGAAGCAA
TCACTCCTGCGACAAGTCCAGTGGGGACCAAGGTTTGTGTAGAGGACCTCTTTTTCAACACGCCTGCACGTCTCAAGTAT
ATGAAGAGCCAGCAGGCGGAGCTGTCTCATATCATTGATATTGTCAACCGTCTGGGTTTGGCCCATCCAGAGATTTCTTT
TAGTTTGATTAGTGATGGCAAGGAAATGACACGAACAGCTGGTACGGGTCAACTACGCCAAGCTATTGCTGGAATTTATG
GTTTGGTCAGTGCCAAGAAGATGATAGCCATTGAGAATTCGGATCTAGACTTTGAAATTACAGGTTTTGTGTCTCTGCCT
GAGTTGACTCGAGCTAATCGCAACTATATCAGCCTCTTCATCAATGGCCGTTATATCAAGAATTTCCTGCTCAATCGTGC
AATTTTGGATGGTTATGGCAGCAAGCTCATGGTGGGACGCTTTCCGCTGGCTGTTATTCATATCCATATTGACCCTTATC
TAGCGGATGTCAATGTGCATCCAACCAAGCAAGAGGTGCGAATTTCTAAGGAAAGAGAGCTGATGGCACTTGTCTCAGAA
GCTATCGCAAAGAGTCTTAAGGAACAGACCTTGATACCGGATGCCTTGGAAAATCTTGCCAAGTCGACCGTGCGCAATCG
TCAAAAGGTGGAGCAGACTATTCTCCCACTCAAAGAAAATACGCTCTACTATGAAAAAACAGAACTCTCAAAACCCAGTC
AAGCTGAGGTGGCTGATCATCAGGTTGAATTAACTGAGGAAGGGCAGGATTTAACCCTGTTTGCCAAGGAAACCTTGGAT
CAGCTAACCAAGCCCGCAAAACTGCATTTTGCAGAGAGAAAGCCTGCTAACTATGACCAACTAGACCATCCAGAGTTAGA
CCTTGCTAGTCTCGATAAGGCCTATGACAAGTTGGAGCGGGAAGAATCTTCAAGCTTCCCAGAGTTGGAATTTTTCGGGC
AAATGCACGGGACTTATCTCTTTGCCCAGGGGCGAGATGGACTCTATATCATTGACCAGCATGCAGCTCAGGAGCGGGTT
AAGTACGAGGAGTATCGTGAAAGCATCGGCAATGTTGACCAGAGCCAGCAACAACTCCTAGTACCCTATATCTTTGAATT
TCCTGCGGATGATGCCCTTCGTCTTAGGGAAAGAATGCCTCTCTTAGAGGAAGTGGGCGTCTTTCTAGCAGAGTACGGAG
AAAATCAATTTATCCTACGTGAACATCCTATTTGGATGGCAGAAGAAGAGATTGAGTCAGGTATCTATGAAATGTGCGAC
ATGCTGCTCTTGACTAAGGAAGTTTCTATCAAAAAATACCGAGCAGAGCTAGCCATCATGATGTCCTGCAAGCGGTCTAT
CAAGGCCAACCATCGTATCGATGACCATTCAGCTCGACAGCTCCTTTATCAGCTTTCTCAATGTGACAATCCATATAACT
GTCCCCATGGACGTCCTGTTTTGGTGCATTTTACCAAGTCAGACATGGAAAAGATGTTCCGACGCATTCAGGAAAATCAC
ACCAGTCTCCGTGAGTTGGGGAAATATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(450-592)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

96.61

100

0.966