Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   MP387_RS07170 Genome accession   NZ_CP094226
Coordinates   1467303..1469216 (-) Length   637 a.a.
NCBI ID   WP_242745919.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1462303..1474216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS07145 (MP387_07145) - 1462434..1463399 (+) 966 WP_242745916.1 LacI family DNA-binding transcriptional regulator -
  MP387_RS07150 (MP387_07150) - 1463435..1464709 (-) 1275 WP_242745917.1 hydroxymethylglutaryl-CoA reductase, degradative -
  MP387_RS07155 (MP387_07155) - 1464709..1465881 (-) 1173 WP_242745918.1 hydroxymethylglutaryl-CoA synthase -
  MP387_RS07160 (MP387_07160) - 1466000..1466455 (-) 456 WP_000176902.1 threonine/serine exporter family protein -
  MP387_RS07165 (MP387_07165) - 1466457..1467215 (-) 759 WP_000344542.1 threonine/serine exporter family protein -
  MP387_RS07170 (MP387_07170) stkP 1467303..1469216 (-) 1914 WP_242745919.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  MP387_RS07175 (MP387_07175) - 1469213..1469953 (-) 741 WP_000401527.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  MP387_RS07180 (MP387_07180) rsmB 1469969..1471282 (-) 1314 WP_242745920.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  MP387_RS07185 (MP387_07185) fmt 1471275..1472210 (-) 936 WP_242745921.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 637 a.a.        Molecular weight: 69243.49 Da        Isoelectric Point: 8.6966

>NTDB_id=577243 MP387_RS07170 WP_242745919.1 1467303..1469216(-) (stkP) [Streptococcus oralis strain 1648]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KPTQPVAEPAPAPKPAKKRKFKARYMILLASLLLVAASLVWILSRTPATIAIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTEVVAELKEKKVPENLIKMEEEESNESEPGIV
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPNYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTAEGTVVSQTP
RAGELVDLASTRIKLSIYKPKTPPSTSSSNPAQHGNQGSPTSPNQGNQQGNQQGNQQGNTPSSSSSNSEGSHESSRD

Nucleotide


Download         Length: 1914 bp        

>NTDB_id=577243 MP387_RS07170 WP_242745919.1 1467303..1469216(-) (stkP) [Streptococcus oralis strain 1648]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGACGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACGGACCCGATTG
CTGTGGCACGTTTCCAGCGTGAAGCGAGGGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTACCTAGCTATGGAATACGTAGCAGGTCTTGACCTCAAGCGTTATATTAAAGAACACTATCC
TCTTTCAAACGAAGAAGCGGTTCGGATTATGGGGCAAATCCTCTTGGCCATGCGCTTAGCCCATACTCGAGGAATCGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCTGACGGCACAGCTAAGGTTACGGACTTTGGGATTGCCGTAGCC
TTTGCGGAGACCAGTCTGACCCAGACAAACTCAATGTTAGGCTCTGTTCATTATTTGTCACCTGAGCAAGCGCGTGGTTC
AAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAAATGCTTACGGGACATATCCCTTATGATG
GGGATAGTGCGGTTACGATTGCCCTCCAGCATTTCCAGAAGCCACTTCCGTCCGTCATAGCTGAAAACCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCAACTGCTAAGAAGCTGTCAGACCGTTATCAGTCTGTTTCAGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGGAATGAACCGAAACTGGTCTTTGACGATGCGAGTAAGGCAGACACTA
AGACTTTACCTAAAGTTCCACAAAGTACACTGACATCGATTCCTAAAGCTCCGGCGCAAGAAGAACGCCCTCAGCCAAAG
AAACCAACTCAACCAGTGGCAGAGCCGGCTCCAGCGCCAAAGCCAGCCAAGAAACGGAAGTTTAAGGCTCGCTATATGAT
TCTTTTGGCTAGTCTTCTATTGGTTGCAGCCTCTTTGGTCTGGATTTTGTCAAGAACACCAGCAACGATTGCTATTCCTG
ACGTAGCTGGACAAACCGTTGCAGAGGCTAAGGAAGCTCTTAAAAAATCCAAGTTTGAAGCCGGTGAAGAAAAGTCAGAG
GCCAGCGATACCGTAGCAGAAGGACGTGTTATTCGAACGGATCCAGAAGCTGGTAGCGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATCGTTTCTTCTGGTAAGCAATCCTTCCAATTGAGCAATTATGTCGGACGTAAGTATACGGAAGTTGTAGCTG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAATGAAAGCGAACCTGGAATCGTC
CTCAGACAGACCCCTGCTTCGGGTTCGACCTATGATCTCTCAAAAGCCACTACGATTACCTTAACAGTGGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACATCGGTTCAAGTCTCGAGTTTACAAAGAATAACTTGACTCAGATTGTCGGTGTGA
AGGAAGCAAATATTGAGGTTGTAGAAGTCTCGACTGCTCCTGAAGGAACGGCAGAAGGAACTGTTGTAAGTCAAACGCCA
AGAGCAGGAGAACTGGTTGATCTTGCAAGTACCCGTATCAAACTTTCCATCTACAAACCAAAAACACCACCATCAACTTC
ATCCTCTAATCCTGCCCAACATGGGAACCAGGGTTCTCCTACAAGTCCAAACCAGGGGAACCAACAAGGAAATCAACAAG
GGAATCAACAAGGGAACACTCCTTCTAGCAGTTCATCCAATAGTGAAGGATCTCACGAAAGTTCTCGAGATTAA

Domains

Predicted by InterProScan.

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(371-432)

PASTA domain (PASTA)

(510-579)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.669

91.994

0.724
  stkP Streptococcus pneumoniae D39

78.328

91.994

0.721
  stkP Streptococcus pneumoniae R6

78.328

91.994

0.721
  stkP Streptococcus pneumoniae Rx1

78.157

91.994

0.719
  pknB Streptococcus mutans UA159

56.153

90.581

0.509
  stkP/pknB Streptococcus salivarius strain HSISS4

52.277

93.093

0.487