Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MM431_RS02390 Genome accession   NZ_CP093068
Coordinates   490107..491231 (+) Length   374 a.a.
NCBI ID   WP_000228553.1    Uniprot ID   -
Organism   Escherichia coli strain BR1220     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 485107..496231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MM431_RS02365 (MM431_02365) mscL 485233..485643 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  MM431_RS02370 (MM431_02370) trkA 485773..487149 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  MM431_RS02375 (MM431_02375) rsmB 487171..488460 (-) 1290 WP_000744778.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  MM431_RS02380 (MM431_02380) fmt 488506..489453 (-) 948 WP_000004473.1 methionyl-tRNA formyltransferase -
  MM431_RS02385 (MM431_02385) def 489468..489977 (-) 510 WP_000114984.1 peptide deformylase -
  MM431_RS02390 (MM431_02390) dprA 490107..491231 (+) 1125 WP_000228553.1 DNA-protecting protein DprA Machinery gene
  MM431_RS02395 (MM431_02395) smg 491203..491676 (+) 474 WP_000460680.1 DUF494 family protein Smg -
  MM431_RS02400 (MM431_02400) yrdD 491705..492247 (+) 543 WP_001129722.1 type I DNA topoisomerase -
  MM431_RS02405 (MM431_02405) tsaC 492252..492824 (+) 573 WP_001301412.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  MM431_RS02410 (MM431_02410) aroE 492829..493647 (+) 819 WP_000451243.1 shikimate dehydrogenase -
  MM431_RS02415 (MM431_02415) yrdB 493644..493901 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  MM431_RS02420 (MM431_02420) yrdA 493877..494431 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40944.88 Da        Isoelectric Point: 6.3122

>NTDB_id=570516 MM431_RS02390 WP_000228553.1 490107..491231(+) (dprA) [Escherichia coli strain BR1220]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFSRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=570516 MM431_RS02390 WP_000228553.1 490107..491231(+) (dprA) [Escherichia coli strain BR1220]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCTCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

47.967

98.663

0.473
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.032

82.888

0.406
  dprA Vibrio cholerae strain A1552

49.032

82.888

0.406
  dprA Haemophilus influenzae Rd KW20

44.807

90.107

0.404
  dprA Glaesserella parasuis strain SC1401

44.51

90.107

0.401
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388