Detailed information NTG0056979

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SAI4T8_RS13480
• Genome accession: NC_020533
• Coordinates: 2658052..2658939 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus subsp. aureus ST228
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2653052..2663939

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAI4T8_RS13445	-	2653071..2653163 (+)	93	WP_010956583.1	hypothetical protein	-
SAI4T8_RS13450 (SAI4T8_1019600)	-	2653271..2653768 (-)	498	WP_001065268.1	glutathione peroxidase	-
SAI4T8_RS13455	-	2653778..2654038 (-)	261	WP_001791974.1	hypothetical protein	-
SAI4T8_RS13460	-	2654420..2654533 (-)	114	Protein_2556	hypothetical protein	-
SAI4T8_RS13470 (SAI4T8_1019610)	-	2655192..2657192 (-)	2001	WP_000776751.1	ABC transporter permease	-
SAI4T8_RS13475 (SAI4T8_1019620)	-	2657189..2657944 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SAI4T8_RS13480 (SAI4T8_1019630)	braS	2658052..2658939 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SAI4T8_RS13485 (SAI4T8_1019640)	braR	2658950..2659615 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAI4T8_RS13490	-	2659641..2659841 (-)	201	WP_000604730.1	hypothetical protein	-
SAI4T8_RS13500 (SAI4T8_1019650)	-	2660039..2661463 (+)	1425	WP_015445964.1	alkaline phosphatase	-
SAI4T8_RS15015	-	2661533..2661643 (+)	111	Protein_2563	hypothetical protein	-
SAI4T8_RS13505 (SAI4T8_1019660)	-	2661746..2662201 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SAI4T8_RS13510 (SAI4T8_1019670)	-	2662446..2663207 (-)	762	WP_015445965.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=56979 SAI4T8_RS13480 WP_000143425.1 2658052..2658939(-) (braS) [Staphylococcus aureus subsp. aureus ST228]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=56979 SAI4T8_RS13480 WP_000143425.1 2658052..2658939(-) (braS) [Staphylococcus aureus subsp. aureus ST228]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1