Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   KIP81_RS02605 Genome accession   NZ_CP075172
Coordinates   495919..497796 (+) Length   625 a.a.
NCBI ID   WP_243603108.1    Uniprot ID   -
Organism   Streptococcus equinus strain SheepZ001     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 490919..502796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIP81_RS02590 (KIP81_02600) fmt 492897..493832 (+) 936 WP_074567269.1 methionyl-tRNA formyltransferase -
  KIP81_RS02595 (KIP81_02605) rsmB 493822..495144 (+) 1323 WP_243603107.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KIP81_RS02600 (KIP81_02610) - 495182..495919 (+) 738 WP_024344649.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KIP81_RS02605 (KIP81_02615) pknB 495919..497796 (+) 1878 WP_243603108.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  KIP81_RS02610 (KIP81_02620) liaF 497940..498635 (+) 696 WP_027968110.1 cell wall-active antibiotics response protein LiaF -
  KIP81_RS02615 (KIP81_02625) - 498632..499657 (+) 1026 WP_243603109.1 sensor histidine kinase -
  KIP81_RS02620 (KIP81_02630) - 499641..500285 (+) 645 WP_024344653.1 response regulator transcription factor -
  KIP81_RS02625 (KIP81_02635) - 500409..501809 (+) 1401 WP_243603110.1 Cof-type HAD-IIB family hydrolase -
  KIP81_RS02630 (KIP81_02640) - 501809..502165 (+) 357 WP_027968108.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 625 a.a.        Molecular weight: 68133.88 Da        Isoelectric Point: 5.4438

>NTDB_id=568236 KIP81_RS02605 WP_243603108.1 495919..497796(+) (pknB) [Streptococcus equinus strain SheepZ001]
MIQIGKLFAGRYRILKSIGRGGMADVYLAKDLILDNEEVAIKVLRTNYQTDQIAVARFQREARAMAELNHPNIVSIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQQGIVHRDLKPQNILLTKDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENKNVP
QALENVVIKATAKRLSDRYASTFEMSRDLMTALSYNRSRERKLVFEDTENTKTLPKVTTSTPVPSTTEQLLKKQKAAKEN
KEVANQKAPKAKAKKKKSHRMFGTLMKIFFAVVVVAIAIFTYLTLSTPASVNVPDVSGAALSDAKTSLLSSGLKIGDIHK
VSSDTVAEGYVVKTDPTAGSSKKEGAKVDIYVSKGSSEFKMKDYTGQNYQDVIKELENKHGISSKMIDIEWVADTSYNSG
TIISQTPEEGTKVGSKDKITFEVAAITMPSLIGYTYQEAIAELNSMGVSSSHITIYMADATSSTGYSRVNSVSSSAVVVA
QDPYYGGAVEGEVNLYFSSETAAQPSEEPSQSVPESSETSETSESSSSSSSSTEESSEASTEMQQ

Nucleotide


Download         Length: 1878 bp        

>NTDB_id=568236 KIP81_RS02605 WP_243603108.1 495919..497796(+) (pknB) [Streptococcus equinus strain SheepZ001]
ATGATTCAGATTGGCAAATTATTTGCTGGTCGTTATCGTATCCTTAAATCAATCGGACGGGGTGGAATGGCAGATGTTTA
TCTTGCCAAAGATCTGATTCTTGATAATGAAGAAGTAGCCATTAAAGTTCTTCGGACTAATTATCAAACAGATCAAATTG
CCGTAGCTCGTTTCCAACGTGAAGCGCGCGCCATGGCAGAGTTGAACCATCCCAATATTGTTTCGATTCGAGATATTGGA
GAAGAAGACGGACAGCAATTCTTAGTAATGGAATATGTTGATGGTTCTGACTTGAAAAAATATATTCAAGATCATGCGCC
TCTATCTAATAACGAAGTTGTTAGAATTATGGAAGAAGTCTTGTCAGCAATGACTCTTGCCCATCAACAAGGAATTGTTC
ACCGTGACTTAAAACCACAAAATATTTTGTTGACTAAAGACGGAACTGTAAAAGTTACTGACTTTGGTATTGCTGTAGCT
TTTGCAGAAACAAGTTTAACACAGACAAACTCAATGCTTGGTAGTGTGCATTATTTGTCACCTGAACAAGCGCGCGGTTC
AAAAGCTACTGTTCAAAGTGATATCTATGCTATGGGGATTATGTTATTTGAAATGTTAACAGGTCACATTCCTTATGATG
GGGATTCAGCTGTTACCATTGCTTTGCAACATTTCCAAAAACCACTTCCATCGATCATTGATGAAAACAAAAATGTTCCT
CAAGCTTTGGAAAATGTAGTTATCAAAGCAACAGCAAAACGTTTAAGCGACCGTTATGCATCAACGTTTGAAATGAGTCG
TGATTTGATGACGGCACTTTCATACAACCGTAGTCGAGAACGTAAACTTGTTTTTGAGGATACAGAAAATACTAAGACAC
TTCCAAAAGTGACTACTTCAACACCTGTTCCATCAACGACAGAACAATTGTTGAAAAAACAAAAAGCTGCAAAAGAAAAT
AAAGAAGTAGCTAATCAAAAAGCACCTAAAGCCAAGGCTAAAAAGAAAAAATCTCATCGTATGTTTGGTACTTTGATGAA
AATCTTCTTTGCAGTCGTTGTTGTTGCGATTGCTATCTTTACTTACTTAACTTTAAGTACACCAGCTTCAGTCAATGTTC
CAGATGTATCTGGTGCGGCTTTATCTGATGCTAAGACAAGCTTGTTATCATCTGGTTTGAAGATTGGTGATATCCACAAA
GTTTCTAGTGATACAGTTGCTGAAGGTTACGTTGTTAAAACAGATCCGACTGCTGGTTCATCTAAGAAAGAAGGAGCTAA
AGTTGATATTTATGTATCAAAAGGAAGTTCTGAATTCAAGATGAAAGATTACACTGGCCAAAATTATCAAGATGTCATCA
AGGAGCTTGAAAATAAACATGGTATTTCAAGTAAAATGATTGATATCGAGTGGGTAGCTGATACTTCATATAATAGTGGT
ACTATTATTAGCCAAACTCCAGAAGAAGGAACAAAAGTTGGTAGTAAAGATAAAATTACTTTTGAAGTAGCAGCAATCAC
AATGCCTAGTCTGATTGGTTATACTTACCAAGAAGCGATTGCTGAGTTAAATTCTATGGGTGTATCAAGCTCACATATTA
CAATTTATATGGCAGATGCAACTTCATCAACAGGATATTCTCGAGTAAACTCAGTATCAAGTTCTGCGGTCGTCGTTGCT
CAGGATCCTTATTATGGTGGGGCTGTTGAAGGAGAGGTTAACCTTTACTTCTCTTCAGAAACGGCTGCGCAACCATCTGA
AGAACCGTCACAATCAGTTCCAGAATCATCTGAAACAAGTGAGACAAGTGAATCAAGTTCATCAAGTAGTAGTAGTACTG
AAGAAAGTTCAGAAGCATCTACTGAAATGCAACAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(506-578)

PASTA domain (PASTA)

(371-434)

PASTA domain (PASTA)

(440-503)

Protein kinase domain (Pkinase)

(12-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

66.9

91.36

0.611
  stkP/pknB Streptococcus salivarius strain HSISS4

64.007

94.24

0.603
  stkP Streptococcus pneumoniae TIGR4

57.827

86.88

0.502
  stkP Streptococcus pneumoniae D39

57.643

86.88

0.501
  stkP Streptococcus pneumoniae R6

57.643

86.88

0.501
  stkP Streptococcus pneumoniae Rx1

57.459

86.88

0.499