Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KIP81_RS01985 Genome accession   NZ_CP075172
Coordinates   369226..369987 (+) Length   253 a.a.
NCBI ID   WP_039691988.1    Uniprot ID   -
Organism   Streptococcus equinus strain SheepZ001     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 364226..374987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KIP81_RS01970 (KIP81_01980) - 364632..366203 (-) 1572 WP_074567328.1 ABC transporter permease subunit -
  KIP81_RS01975 (KIP81_01985) - 366340..368232 (+) 1893 WP_243603059.1 DUF2207 domain-containing protein -
  KIP81_RS01980 (KIP81_01990) - 368284..369123 (+) 840 WP_243603060.1 undecaprenyl-diphosphate phosphatase -
  KIP81_RS01985 (KIP81_01995) mecA 369226..369987 (+) 762 WP_039691988.1 adaptor protein MecA Regulator
  KIP81_RS01990 (KIP81_02000) - 369989..371152 (+) 1164 WP_024344760.1 MraY family glycosyltransferase -
  KIP81_RS01995 (KIP81_02005) sufC 371274..372044 (+) 771 WP_003067585.1 Fe-S cluster assembly ATPase SufC -
  KIP81_RS02000 (KIP81_02010) sufD 372122..373384 (+) 1263 WP_243603061.1 Fe-S cluster assembly protein SufD -
  KIP81_RS02005 (KIP81_02015) - 373386..374618 (+) 1233 WP_243603062.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29055.86 Da        Isoelectric Point: 4.0441

>NTDB_id=568230 KIP81_RS01985 WP_039691988.1 369226..369987(+) (mecA) [Streptococcus equinus strain SheepZ001]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINFEDLAAFDDVSNMSPEEFFKTLEQTMMAKGDTEAHEKLGKIEEMMEGAVEEVLTEHAKQADTEPEEDVNPSDYVH
YVLDFPSLEATVAFSKAIDFPVEASELYKMDGAYYMTILLDLQNQPSYYANLMYARMLEYAGAGTKTRAYLQEHAVELLT
DDAVAKLKMIELV

Nucleotide


Download         Length: 762 bp        

>NTDB_id=568230 KIP81_RS01985 WP_039691988.1 369226..369987(+) (mecA) [Streptococcus equinus strain SheepZ001]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGAGGAATGGAGTT
AAAAGACTTTTTGATTCCGCAAGAAAAGACAGAAGAGTTCTTCTATTCAGTAATGGATGAGTTAGATTTACCAGATAATT
TCAAAGATAGCGGCATGCTTAGCTTTCGTGTGACACCACGTAAAGACCGTCTTGATGTATTTGTCACAAAATCAGAAATC
AACAAAGATATCAATTTTGAAGATTTAGCTGCATTTGATGATGTGTCTAACATGTCACCAGAAGAATTCTTTAAAACGCT
AGAACAAACAATGATGGCTAAAGGTGACACTGAAGCTCATGAAAAATTAGGTAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAAGAAGTCTTGACAGAGCACGCTAAGCAAGCAGATACAGAACCTGAAGAAGATGTAAATCCATCTGATTATGTTCAT
TACGTCTTAGATTTTCCAAGTTTAGAAGCAACAGTTGCTTTTTCTAAAGCGATTGATTTTCCTGTGGAAGCTTCTGAACT
TTACAAGATGGACGGCGCTTATTACATGACAATTTTGCTTGATTTGCAGAACCAACCTTCTTATTATGCAAATTTGATGT
ATGCCCGTATGTTAGAATACGCTGGCGCTGGTACAAAAACTCGTGCTTACTTACAAGAGCACGCAGTTGAACTATTGACG
GATGATGCCGTTGCAAAATTAAAAATGATTGAGTTGGTATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

66.4

98.814

0.656
  mecA Streptococcus thermophilus LMD-9

60.643

98.419

0.597
  mecA Streptococcus thermophilus LMG 18311

59.839

98.419

0.589
  mecA Streptococcus pneumoniae Rx1

49.02

100

0.494
  mecA Streptococcus pneumoniae D39

49.02

100

0.494
  mecA Streptococcus pneumoniae R6

49.02

100

0.494
  mecA Streptococcus pneumoniae TIGR4

49.02

100

0.494