Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SITYG_RS09100 Genome accession   NZ_AP014880
Coordinates   1790605..1790898 (-) Length   97 a.a.
NCBI ID   WP_003073987.1    Uniprot ID   T1ZHP4
Organism   Streptococcus intermedius strain TYG1620     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1785605..1795898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS09080 (SITYG_17980) - 1787587..1788786 (-) 1200 WP_009569506.1 acetate kinase -
  SITYG_RS09085 (SITYG_17990) comGH 1788833..1789786 (-) 954 WP_096363205.1 class I SAM-dependent methyltransferase Machinery gene
  SITYG_RS09090 (SITYG_18000) comGG/cglG 1789877..1790203 (-) 327 WP_020999196.1 competence type IV pilus minor pilin ComGG Machinery gene
  SITYG_RS09095 (SITYG_18010) comGF/cglF 1790184..1790621 (-) 438 WP_003073990.1 competence type IV pilus minor pilin ComGF Machinery gene
  SITYG_RS09100 (SITYG_18020) comGE/cglE 1790605..1790898 (-) 294 WP_003073987.1 competence type IV pilus minor pilin ComGE Machinery gene
  SITYG_RS09105 (SITYG_18030) comGD 1790870..1791298 (-) 429 WP_096363206.1 competence type IV pilus minor pilin ComGD Machinery gene
  SITYG_RS09110 (SITYG_18040) comGC 1791258..1791575 (-) 318 WP_003075998.1 competence type IV pilus major pilin ComGC Machinery gene
  SITYG_RS09115 (SITYG_18050) comGB 1791572..1792594 (-) 1023 WP_173672242.1 competence type IV pilus assembly protein ComGB Machinery gene
  SITYG_RS09120 (SITYG_18060) comGA 1792536..1793477 (-) 942 WP_096363208.1 competence type IV pilus ATPase ComGA Machinery gene
  SITYG_RS09125 (SITYG_18070) - 1793546..1793911 (-) 366 WP_009569514.1 DUF1033 family protein -
  SITYG_RS09130 (SITYG_18080) - 1794040..1794756 (-) 717 WP_009569515.1 TipC family immunity protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11195.24 Da        Isoelectric Point: 10.4670

>NTDB_id=56568 SITYG_RS09100 WP_003073987.1 1790605..1790898(-) (comGE/cglE) [Streptococcus intermedius strain TYG1620]
MENLRKQYVRGTILLEALLALAIFATIVTLLLGQIHQSRKLENELLKKEEVLRVAKMALQTNQRHLTMNGIEVRVEKSQQ
DIRVYHGKELIFGVQSK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=56568 SITYG_RS09100 WP_003073987.1 1790605..1790898(-) (comGE/cglE) [Streptococcus intermedius strain TYG1620]
ATGGAAAATTTAAGAAAACAATATGTTAGAGGGACAATTTTATTAGAAGCACTGCTTGCGTTAGCTATTTTTGCGACAAT
TGTAACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAACTAGAAAATGAGTTATTGAAAAAAGAAGAAGTCTTAAGGG
TAGCGAAGATGGCCTTGCAAACAAATCAAAGGCATTTAACAATGAACGGTATTGAAGTACGTGTCGAAAAAAGCCAACAA
GATATTCGGGTTTATCATGGGAAGGAGCTGATTTTTGGTGTTCAAAGCAAATAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-91)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZHP4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae D39

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae R6

56.522

94.845

0.536
  comGE/cglE Streptococcus pneumoniae TIGR4

56.522

94.845

0.536
  comGE/cglE Streptococcus mitis NCTC 12261

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis SK321

55.435

94.845

0.526
  comGE Streptococcus mutans UA140

48.352

93.814

0.454
  comGE Streptococcus mutans UA159

48.352

93.814

0.454

Multiple sequence alignment