Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   MF614_RS02365 Genome accession   NZ_CP092252
Coordinates   479303..480427 (+) Length   374 a.a.
NCBI ID   WP_239371263.1    Uniprot ID   -
Organism   Escherichia coli strain ISHS7     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 474303..485427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MF614_RS02340 (MF614_02340) mscL 474429..474839 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  MF614_RS02345 (MF614_02345) trkA 474969..476345 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  MF614_RS02350 (MF614_02350) rsmB 476367..477656 (-) 1290 WP_000744779.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  MF614_RS02355 (MF614_02355) fmt 477702..478649 (-) 948 WP_000004454.1 methionyl-tRNA formyltransferase -
  MF614_RS02360 (MF614_02360) def 478664..479173 (-) 510 WP_000114984.1 peptide deformylase -
  MF614_RS02365 (MF614_02365) dprA 479303..480427 (+) 1125 WP_239371263.1 DNA-protecting protein DprA Machinery gene
  MF614_RS02370 (MF614_02370) smg 480399..480872 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  MF614_RS02375 (MF614_02375) yrdD 480901..481443 (+) 543 WP_001129719.1 type I DNA topoisomerase -
  MF614_RS02380 (MF614_02380) tsaC 481448..482020 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  MF614_RS02385 (MF614_02385) aroE 482025..482843 (+) 819 WP_000451211.1 shikimate dehydrogenase -
  MF614_RS02390 (MF614_02390) yrdB 482840..483097 (+) 258 WP_001070603.1 DUF1488 domain-containing protein -
  MF614_RS02395 (MF614_02395) yrdA 483073..483627 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40958.91 Da        Isoelectric Point: 6.3122

>NTDB_id=564869 MF614_RS02365 WP_239371263.1 479303..480427(+) (dprA) [Escherichia coli strain ISHS7]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLVTTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFTELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=564869 MF614_RS02365 WP_239371263.1 479303..480427(+) (dprA) [Escherichia coli strain ISHS7]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGTGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGGTTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTCTGCT
TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTACTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(311-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.238

98.663

0.476
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

44.595

98.93

0.441
  dprA Vibrio cholerae strain A1552

44.595

98.93

0.441
  dprA Glaesserella parasuis strain SC1401

44.543

90.642

0.404
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393
  dprA Haemophilus influenzae Rd KW20

49.306

77.005

0.38