Detailed information NTG0564449

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: KGS74_RS12560
• Genome accession: NZ_CP074377
• Coordinates: 2665431..2667623 (+)
• Length: 730 a.a.
• NCBI ID: WP_049171302.1
• Uniprot ID: -
• Organism: Lacticaseibacillus casei strain FBL6
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2660431..2672623

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KGS74_RS12530 (KGS74_12530)	-	2660712..2660909 (+)	198	WP_213291503.1	ComC/BlpC family peptide pheromone/bacteriocin	-
KGS74_RS12535 (KGS74_12535)	-	2660937..2661095 (+)	159	WP_047105543.1	hypothetical protein	-
KGS74_RS12540 (KGS74_12540)	-	2662231..2662512 (+)	282	WP_049171294.1	hypothetical protein	-
KGS74_RS12545 (KGS74_12545)	-	2662693..2663499 (-)	807	WP_049171298.1	response regulator transcription factor	-
KGS74_RS12550 (KGS74_12550)	-	2663501..2664802 (-)	1302	WP_049171300.1	GHKL domain-containing protein	-
KGS74_RS12555 (KGS74_12555)	-	2664971..2665117 (+)	147	WP_191978410.1	hypothetical protein	-
KGS74_RS12560 (KGS74_12560)	comA	2665431..2667623 (+)	2193	WP_049171302.1	peptide cleavage/export ABC transporter	Regulator
KGS74_RS12565 (KGS74_12565)	-	2667635..2669014 (+)	1380	WP_049171305.1	bacteriocin secretion accessory protein	-
KGS74_RS12570 (KGS74_12570)	-	2669128..2670483 (+)	1356	WP_049171308.1	threonine/serine exporter family protein	-
KGS74_RS12575 (KGS74_12575)	-	2670770..2671747 (-)	978	WP_213291504.1	aldo/keto reductase	-
KGS74_RS12580 (KGS74_12580)	-	2672049..2672216 (-)	168	WP_155807535.1	hypothetical protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81556.09 Da
• Isoelectric Point: 7.5911

>NTDB_id=564449 KGS74_RS12560 WP_049171302.1 2665431..2667623(+) (comA) [Lacticaseibacillus casei strain FBL6]
MFKYKFKLGQAKYFKRYYTPQVDERDCGVAALNMLLKFHGSDYSLAHLRQLAKTDQEGTTALGIVRAAQELHFETKAVKA
DMTLFDLDDAPYPILVHVLKRGELSHYYVVFKATKDHILIGDPDPSVAMTWLSKEEFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPLLARQKVIIANIIVAALLITMISIVGSYFLQSIIDTYIPSAMRTTLGMIASGLILAYILQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFATRRTGEIVSRFSDANKIIDALANTIMTLFLDVWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYAKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLSYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRHLTDRSLIDGAIIVNDVSFKYGFGQDILKHVHLEVPANAKYTIVGMSGSGKSTLAKLLVGFYPVETGRGKITFNGAQI
DDVALTTLRQYIEYVPQEPFIFSGSVMENLTLGSRADLTQAQLEDACAVAEIATDIMNLPQMWQTKLTESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERRIVDRLLAMKDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=564449 KGS74_RS12560 WP_049171302.1 2665431..2667623(+) (comA) [Lacticaseibacillus casei strain FBL6]
ATGTTCAAATACAAATTTAAACTAGGCCAAGCAAAATACTTCAAACGCTATTACACGCCTCAGGTGGATGAGCGTGATTG
CGGCGTTGCGGCGCTTAATATGTTGCTGAAGTTTCATGGGTCCGACTATTCGCTCGCACATTTACGGCAATTAGCAAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGCATTGTTCGTGCTGCCCAGGAACTTCATTTTGAAACCAAGGCAGTTAAGGCG
GATATGACGTTGTTTGATTTGGATGATGCGCCATATCCGATTTTGGTTCATGTTTTGAAGCGCGGCGAGTTGTCGCATTA
TTATGTCGTGTTTAAGGCGACGAAGGATCATATCTTAATCGGTGATCCTGACCCTTCAGTCGCGATGACCTGGCTTTCAA
AAGAGGAGTTTGCCAAGGAGTGGTCGGGGGTGGCTATCTTTATTGCTCCTGAACCGCAATATCAACCGCGCAAAGAGGAC
AAAGGCAGTTTGTTTGCCTTCGTGCCGTTGCTCGCGCGGCAAAAAGTGATCATTGCCAATATTATTGTGGCGGCTTTGTT
GATCACGATGATTAGCATTGTTGGGTCGTATTTTCTGCAATCGATCATTGATACCTACATTCCAAGTGCCATGCGGACGA
CGTTAGGGATGATCGCCAGTGGGCTGATTCTCGCCTACATTCTCCAATCCGTTTTGACGTATGGCCAGAATTTCTTGATG
GCGGTTTTAGGCCAGCGATTGTCGATTGACGTTATTTTAGGTTACGTTCGGCATCTGTATGAATTACCCATGTCCTTTTT
TGCAACGCGCCGGACAGGGGAGATTGTGTCGCGGTTTTCGGATGCCAATAAAATTATCGATGCCTTGGCGAATACGATTA
TGACCCTGTTTCTTGACGTTTGGATCGTGCTTATTTTAGGCATTGTTTTGGGCATTCAAAATACCACATTGTTCCTGGTG
TCCTTAATTGCGGTGCCTTGTTACTTGGTGATTGTTTTCGCGTTTCAACGTCCTTTCAATCGGCTGAATCAAGAGACAAT
GGAAAGCAATGCCATTTTGAGCTCATCGATTATTGAGGATCTGAACGGTATTGAGACCATTAAGTCGCTGACAGGCGAAA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTTACGTATTTAAAAAAGTCATTCAATTACGCGAAAGCTGACCAACTT
CAACAAGCCATCAAGGGGTTGCTGAAACTCGTCTTGAATGTGGTGGTGTTGTGGATTGGGGCGAGTCTGGTGATGGCTAA
CAAGATGAGCTTGGGGCAGATGCTGACGTTCAATGCCTTGCTGTCATACTTCACCAATCCGTTAGAAAGCATCATTAACT
TGCAACCAAAATTGCAAATGGCTAAGGTGGCGAATAATCGGCTGAATGAGGTTTATTTGGTTGAATCTGAGTTTAAAGAA
CAGCGCCATCTGACCGATCGCAGCTTGATCGATGGCGCCATCATTGTGAATGACGTTTCTTTTAAGTATGGATTTGGTCA
GGATATTTTGAAGCATGTCCATCTTGAAGTGCCCGCAAACGCTAAATACACGATTGTCGGCATGAGTGGGTCAGGTAAAT
CAACTTTGGCCAAATTATTGGTCGGTTTTTACCCGGTCGAAACAGGCAGGGGGAAAATCACTTTTAATGGCGCGCAGATC
GATGATGTGGCGCTCACGACGCTACGGCAATATATCGAGTATGTGCCGCAAGAACCATTTATTTTTTCCGGATCGGTGAT
GGAAAACTTAACGTTAGGCAGTCGTGCCGATTTGACGCAGGCGCAACTTGAAGACGCATGTGCTGTTGCGGAGATTGCCA
CGGATATTATGAATCTGCCGCAAATGTGGCAGACCAAGCTCACGGAAAGCGGGAGCATTTTATCAGGCGGGCAGAAGCAG
CGATTGGCGATTGCGCGAGCACTGTTGTCGCCGGCCAAAGTGCTGATTTTTGATGAGTCAACTAGCAGTCTGGATACCAT
TACAGAACGGCGGATTGTGGATCGATTGTTGGCAATGAAGGATCGAACGATTATTTTTGTTGCGCACCGACTCACCATCG
CGGCTAAAACCGAGCAGATCGTGGTGATGGATCACGGGGCAATTGTTGAGCAGGGCAATCATGCCGAACTGCTGGCGAAG
CAGGGATATTATGCGCGGTTGGTGAGTGAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (180-448)

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter (ABC_tran) (510-662)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.217	98.356	0.573
comA	Streptococcus pneumoniae Rx1	58.078	98.356	0.571
comA	Streptococcus pneumoniae D39	58.078	98.356	0.571
comA	Streptococcus pneumoniae R6	58.078	98.356	0.571
comA	Streptococcus mitis SK321	57.66	98.356	0.567
comA	Streptococcus pneumoniae TIGR4	57.66	98.356	0.567
comA	Streptococcus gordonii str. Challis substr. CH1	56.685	98.356	0.558
comA/nlmT	Streptococcus mutans UA159	54.986	98.904	0.544