Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   KFZ55_RS01250 Genome accession   NZ_CP074114
Coordinates   266035..267303 (-) Length   422 a.a.
NCBI ID   WP_061840691.1    Uniprot ID   A0A2H6CVH6
Organism   Tetragenococcus halophilus strain SNTH-1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 261035..272303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFZ55_RS01215 (KFZ55_01210) pepV 261118..262530 (+) 1413 WP_061840695.1 dipeptidase PepV -
  KFZ55_RS01220 (KFZ55_01215) - 262639..262980 (-) 342 WP_014123644.1 PepSY domain-containing protein -
  KFZ55_RS01225 (KFZ55_01220) - 263072..263224 (-) 153 Protein_245 aminoglycoside 6-adenylyltransferase -
  KFZ55_RS01230 (KFZ55_01225) pepA 263368..264444 (+) 1077 WP_103103630.1 glutamyl aminopeptidase -
  KFZ55_RS01235 (KFZ55_01230) - 264532..264846 (+) 315 WP_014123647.1 thioredoxin family protein -
  KFZ55_RS01240 (KFZ55_01235) - 264869..265327 (+) 459 WP_014123648.1 universal stress protein -
  KFZ55_RS01245 (KFZ55_01240) ytpR 265380..265991 (+) 612 WP_094244016.1 YtpR family tRNA-binding protein -
  KFZ55_RS01250 (KFZ55_01245) htrA 266035..267303 (-) 1269 WP_061840691.1 S1C family serine protease Regulator
  KFZ55_RS01255 (KFZ55_01250) rlmH 267645..268124 (+) 480 WP_289942822.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  KFZ55_RS01260 (KFZ55_01255) - 268168..268695 (+) 528 WP_289942823.1 adenylyl-sulfate kinase -
  KFZ55_RS01265 (KFZ55_01260) msrA 268936..269772 (+) 837 WP_041591745.1 peptide-methionine (S)-S-oxide reductase MsrA -
  KFZ55_RS01270 (KFZ55_01265) - 269856..270335 (+) 480 WP_103083696.1 C-GCAxxG-C-C family protein -
  KFZ55_RS01275 (KFZ55_01270) - 270369..271271 (+) 903 WP_289942824.1 TDT family transporter -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 43973.74 Da        Isoelectric Point: 3.7200

>NTDB_id=563493 KFZ55_RS01250 WP_061840691.1 266035..267303(-) (htrA) [Tetragenococcus halophilus strain SNTH-1]
MAKKNVTPDSKKGGWIKKFGIGLLGGLIGGLLVIGGFYYFSNGNPFQTNEATSSSGVTDNNDDVQVSDVKVDADSDTTDA
VENVQNAVVSVINLQNSSPQESGGIFGTEQPEGNSEDDEEPAGEGSGVIYKEDGGDAYIVTNNHVVAGQSGLEVVMADGS
REQAELVGTDAYTDLAVLKISSDNVDTVATFGDSDELQVGEPAIAIGSPLGSDYANSVTQGIISSVNRLVSSQNESGEDV
STNAIQTDAAINPGNSGGPLVNAGGQVVGINSSKIASSGQAGVSVEGMGFAIPSNDVTDIINELEENGEIARPALGISML
DLNTIPTEQRQRVLQIPEDVENGVVVENPGDGTPASDAGLEQYDVITKVDDKEIKDSTELRAALYEKSVGDTLKLTFYRQ
DDAQSVNVKLSEDQSIIESNNE

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=563493 KFZ55_RS01250 WP_061840691.1 266035..267303(-) (htrA) [Tetragenococcus halophilus strain SNTH-1]
ATGGCAAAAAAGAATGTAACACCTGATTCTAAAAAAGGCGGGTGGATTAAAAAATTCGGAATTGGCCTATTAGGTGGATT
AATAGGCGGGTTACTTGTCATTGGTGGCTTTTATTATTTTTCTAATGGTAACCCATTTCAAACAAATGAAGCAACTTCTT
CATCTGGCGTAACAGATAATAACGACGACGTACAGGTCAGTGATGTTAAAGTTGATGCCGATAGTGATACCACAGACGCT
GTAGAAAATGTACAAAATGCTGTCGTTTCAGTGATCAATTTACAAAACTCTTCTCCTCAAGAAAGCGGAGGTATTTTTGG
CACCGAGCAACCAGAAGGCAACTCTGAAGACGACGAGGAGCCAGCTGGTGAAGGTAGTGGTGTGATTTACAAAGAAGATG
GCGGCGATGCCTACATTGTAACAAATAATCACGTAGTTGCCGGACAAAGTGGCTTGGAAGTAGTTATGGCAGACGGTAGT
AGAGAACAAGCAGAATTAGTAGGTACTGATGCTTATACTGACTTAGCCGTATTAAAAATTTCTTCTGATAATGTAGACAC
AGTAGCTACATTCGGTGATTCTGATGAATTACAAGTAGGTGAACCAGCGATCGCTATTGGTTCTCCTCTAGGTTCTGATT
ATGCTAATTCAGTAACCCAAGGAATTATTTCTTCAGTCAATCGTTTAGTATCCAGCCAAAATGAATCTGGCGAAGATGTG
AGCACAAATGCTATTCAAACGGACGCTGCAATCAACCCAGGAAATTCTGGCGGGCCATTGGTCAATGCTGGTGGACAAGT
TGTTGGAATTAACTCCAGTAAAATTGCTAGTTCCGGACAAGCTGGCGTAAGTGTTGAAGGCATGGGCTTTGCTATTCCAA
GTAATGATGTAACAGATATTATTAATGAATTGGAAGAAAATGGTGAAATTGCTCGTCCAGCGTTAGGCATCTCCATGCTT
GATTTAAATACCATTCCTACAGAACAAAGACAACGTGTTTTACAAATCCCTGAGGATGTAGAAAACGGCGTTGTTGTAGA
AAACCCTGGCGATGGCACACCAGCAAGTGATGCAGGATTAGAACAATATGATGTTATTACAAAAGTTGACGATAAAGAAA
TAAAAGATTCTACTGAGCTACGTGCCGCTTTATATGAAAAATCAGTAGGAGATACTTTGAAATTGACTTTTTATCGACAA
GATGACGCACAATCTGTAAATGTTAAACTATCAGAAGATCAATCAATCATTGAAAGCAACAACGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(313-410)

Trypsin-like peptidase domain (Trypsin_2)

(125-270)

Peptidase family M50 (Peptidase_M50)

(317-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2H6CVH6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

58.38

84.834

0.495
  htrA Streptococcus mitis NCTC 12261

50.256

92.417

0.464
  htrA Streptococcus gordonii str. Challis substr. CH1

49.745

92.891

0.462
  htrA Streptococcus pneumoniae TIGR4

49.744

92.417

0.46
  htrA Streptococcus pneumoniae D39

49.744

92.417

0.46
  htrA Streptococcus pneumoniae Rx1

49.744

92.417

0.46
  htrA Streptococcus pneumoniae R6

49.744

92.417

0.46