Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   L6L60_RS01230 Genome accession   NZ_CP091703
Coordinates   254674..255330 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain KOr021     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 249674..260330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6L60_RS01200 (L6L60_01200) dcyD 250554..251540 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  L6L60_RS01205 (L6L60_01205) tcyL 251555..252223 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  L6L60_RS01210 (L6L60_01210) tcyN 252220..252972 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  L6L60_RS01215 (L6L60_01215) sdiA 253202..253924 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  L6L60_RS01220 (L6L60_01220) yecF 253991..254215 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  L6L60_RS01225 (L6L60_01225) yecU 254202..254378 (-) 177 WP_000590344.1 protein YecU -
  L6L60_RS23865 - 254416..254532 (-) 117 WP_023063716.1 hypothetical protein -
  L6L60_RS01230 (L6L60_01230) letA 254674..255330 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  L6L60_RS01235 (L6L60_01235) uvrC 255327..257159 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  L6L60_RS01240 (L6L60_01240) pgsA 257216..257764 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  L6L60_RS01260 (L6L60_01260) yecA 258414..259079 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=563087 L6L60_RS01230 WP_000611328.1 254674..255330(+) (letA) [Escherichia coli strain KOr021]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=563087 L6L60_RS01230 WP_000611328.1 254674..255330(+) (letA) [Escherichia coli strain KOr021]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482