Detailed information NTG0561595

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV45_RS08390
• Genome accession: NZ_CP073862
• Coordinates: 1765857..1766903 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1276219
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1760857..1771903

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV45_RS08360 (KFV45_08370)	-	1761241..1762482 (-)	1242	WP_001832467.1	aminopeptidase	-
KFV45_RS08365 (KFV45_08375)	-	1762484..1762699 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV45_RS08370 (KFV45_08380)	-	1762840..1763304 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV45_RS08375 (KFV45_08385)	-	1763312..1763596 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV45_RS08380 (KFV45_08390)	-	1764003..1765181 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV45_RS08385 (KFV45_08395)	vraR	1765238..1765867 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV45_RS08390 (KFV45_08400)	vraS	1765857..1766903 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV45_RS08395 (KFV45_08405)	liaF	1766900..1767601 (-)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV45_RS08400 (KFV45_08410)	-	1767616..1768002 (-)	387	WP_001830382.1	hypothetical protein	-
KFV45_RS08405 (KFV45_08415)	map	1768160..1768915 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV45_RS08410 (KFV45_08420)	-	1769089..1770075 (+)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV45_RS08415 (KFV45_08425)	-	1770226..1770762 (-)	537	WP_002470337.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561595 KFV45_RS08390 WP_001830374.1 1765857..1766903(-) (vraS) [Staphylococcus epidermidis strain B1276219]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561595 KFV45_RS08390 WP_001830374.1 1765857..1766903(-) (vraS) [Staphylococcus epidermidis strain B1276219]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92