Detailed information NTG0561369

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV50_RS08300
• Genome accession: NZ_CP073847
• Coordinates: 1766928..1767974 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1266875
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1761928..1772974

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV50_RS08270 (KFV50_08280)	-	1762312..1763553 (-)	1242	WP_001832467.1	aminopeptidase	-
KFV50_RS08275 (KFV50_08285)	-	1763555..1763770 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV50_RS08280 (KFV50_08290)	-	1763911..1764375 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV50_RS08285 (KFV50_08295)	-	1764383..1764667 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV50_RS08290 (KFV50_08300)	-	1765074..1766252 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV50_RS08295 (KFV50_08305)	vraR	1766309..1766938 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV50_RS08300 (KFV50_08310)	vraS	1766928..1767974 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV50_RS08305 (KFV50_08315)	liaF	1767971..1768672 (-)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV50_RS08310 (KFV50_08320)	-	1768687..1769073 (-)	387	WP_001830382.1	hypothetical protein	-
KFV50_RS08315 (KFV50_08325)	map	1769231..1769986 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV50_RS08320 (KFV50_08330)	-	1770160..1771146 (+)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV50_RS08325 (KFV50_08335)	-	1771297..1771833 (-)	537	WP_002470337.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561369 KFV50_RS08300 WP_001830374.1 1766928..1767974(-) (vraS) [Staphylococcus epidermidis strain B1266875]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561369 KFV50_RS08300 WP_001830374.1 1766928..1767974(-) (vraS) [Staphylococcus epidermidis strain B1266875]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92