NTDB

Overview

Name	micA	Type	Regulator
Locus tag	KEM15_RS08935	Genome accession	NZ_CP073632
Coordinates	1739983..1740666 (+)	Length	227 a.a.
NCBI ID	WP_274504953.1	Uniprot ID	-
Organism	Streptococcus parasuis strain NN1
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1734983..1745666

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KEM15_RS10320	-	1734986..1735294 (+)	309	WP_277837524.1	GNAT family protein	-
KEM15_RS08905 (KEM15_08770)	-	1735496..1735990 (-)	495	WP_217375195.1	DUF536 domain-containing protein	-
KEM15_RS08910 (KEM15_08775)	-	1736387..1737496 (-)	1110	Protein_1730	IS3 family transposase	-
KEM15_RS08915 (KEM15_08780)	-	1737577..1739019 (-)	1443	WP_274504310.1	multicopper oxidase domain-containing protein	-
KEM15_RS08920 (KEM15_08785)	-	1739173..1739382 (-)	210	Protein_1732	hypothetical protein	-
KEM15_RS08925	-	1739644..1739805 (+)	162	Protein_1733	multicopper oxidase domain-containing protein	-
KEM15_RS08930	-	1739885..1739947 (+)	63	WP_254451669.1	multicopper oxidase domain-containing protein	-
KEM15_RS08935 (KEM15_08795)	micA	1739983..1740666 (+)	684	WP_274504953.1	response regulator transcription factor	Regulator
KEM15_RS08940 (KEM15_08800)	-	1740663..1742060 (+)	1398	WP_274504311.1	ATP-binding protein	-
KEM15_RS08945 (KEM15_08805)	-	1742231..1743439 (-)	1209	WP_274504312.1	cytochrome D1 domain-containing protein	-
KEM15_RS08950 (KEM15_08810)	-	1743714..1743947 (-)	234	WP_043914326.1	amino acid acetyltransferase	-
KEM15_RS08955 (KEM15_08815)	lgt	1743950..1744832 (-)	883	Protein_1739	prolipoprotein diacylglyceryl transferase	-
KEM15_RS08960	-	1744876..1745067 (-)	192	WP_274504313.1	M23 family metallopeptidase	-

Sequence

Protein

Download Length: 227 a.a. Molecular weight: 25654.67 Da Isoelectric Point: 4.9111

                                >NTDB_id=559532 KEM15_RS08935 WP_274504953.1 1739983..1740666(+) (micA) [Streptococcus parasuis strain NN1]

MKILIVDDEASILDIVEAYLSAKGYQVFRALSGNEALTKVDVVQPDLIVLDLMLPGLSGLEVCKKIRDSSTVPIIMLTAK

TAEKDILEGLSLGADDYITKPFSPKELVARVETVLRRVQPEYREEKWSFEEGLLVIYPDRKQVFKQGEEIILTSTEYALL

ALLASHPKRLFSREQLLDAVKGLDFDGTDRVIDTHIKNIRQKIEDDTRNPYFILTAYGMGYRFGGQK

Nucleotide

Download Length: 684 bp

                                >NTDB_id=559532 KEM15_RS08935 WP_274504953.1 1739983..1740666(+) (micA) [Streptococcus parasuis strain NN1]

GTGAAGATTTTAATTGTGGACGACGAAGCAAGCATTCTGGATATCGTGGAAGCCTATTTGAGTGCAAAAGGCTATCAAGT

GTTTCGCGCTTTGAGCGGAAACGAGGCTTTAACAAAGGTTGATGTTGTCCAACCTGACTTGATTGTGTTGGATCTCATGC

TGCCTGGTTTATCTGGCCTCGAAGTCTGTAAAAAAATAAGGGACTCCTCCACTGTACCGATTATCATGTTGACTGCGAAA

ACAGCCGAAAAAGATATCTTGGAAGGGTTAAGCCTGGGGGCTGATGACTACATCACAAAACCATTCAGCCCGAAAGAGCT

GGTTGCTCGGGTCGAAACCGTTTTACGCCGTGTCCAACCAGAATACAGAGAAGAAAAGTGGTCTTTCGAAGAAGGTTTGC

TGGTTATCTACCCGGATCGAAAACAAGTATTCAAACAAGGTGAAGAAATCATTTTGACCTCGACCGAGTATGCTTTATTA

GCCCTTCTGGCCTCACATCCAAAGCGCCTATTTTCACGGGAACAGCTGCTGGACGCTGTGAAAGGACTCGATTTTGATGG

AACGGATCGGGTGATCGATACCCACATCAAAAATATCCGTCAAAAAATTGAGGACGACACGCGCAACCCCTACTTCATCT

TAACCGCATATGGAATGGGGTATCGATTTGGTGGTCAAAAATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-223)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
micA	Streptococcus pneumoniae Cp1015	48.673	99.559	0.485
vicR	Streptococcus mutans UA159	48.458	100	0.485
scnR	Streptococcus mutans UA159	38.865	100	0.392
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.117	98.238	0.374
covR	Streptococcus salivarius strain HSISS4	37.668	98.238	0.37

Detailed information NTG0559532