Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   KEM15_RS08355 Genome accession   NZ_CP073632
Coordinates   1620519..1621235 (-) Length   238 a.a.
NCBI ID   WP_130554705.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NN1     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1615519..1626235
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KEM15_RS08335 (KEM15_08205) - 1615883..1617109 (-) 1227 WP_274504256.1 cysteine desulfurase -
  KEM15_RS08340 (KEM15_08210) sufD 1617114..1618376 (-) 1263 WP_217374211.1 Fe-S cluster assembly protein SufD -
  KEM15_RS08345 (KEM15_08215) sufC 1618393..1619166 (-) 774 WP_171989104.1 Fe-S cluster assembly ATPase SufC -
  KEM15_RS08350 (KEM15_08220) - 1619338..1620522 (-) 1185 WP_217374212.1 MraY family glycosyltransferase -
  KEM15_RS08355 (KEM15_08225) mecA 1620519..1621235 (-) 717 WP_130554705.1 adaptor protein MecA Regulator
  KEM15_RS08360 (KEM15_08230) - 1621439..1622278 (-) 840 WP_274504947.1 undecaprenyl-diphosphate phosphatase -
  KEM15_RS08365 (KEM15_08235) - 1622554..1624116 (+) 1563 WP_274504257.1 ABC transporter substrate-binding protein/permease -
  KEM15_RS08370 (KEM15_08240) - 1624109..1624852 (+) 744 WP_130554708.1 amino acid ABC transporter ATP-binding protein -
  KEM15_RS08375 (KEM15_08245) - 1624960..1625169 (-) 210 WP_024391394.1 hypothetical protein -
  KEM15_RS08380 (KEM15_08250) - 1625259..1626161 (-) 903 WP_274504258.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27881.56 Da        Isoelectric Point: 4.1340

>NTDB_id=559529 KEM15_RS08355 WP_130554705.1 1620519..1621235(-) (mecA) [Streptococcus parasuis strain NN1]
MKVKQISDSTLKITIQLEDLEERGMEIADFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDKVDIFVTKSEM
DQSLNFDEFTDLSELGDVSRMTPDELLKSLERTVRERSTHDSKAVRLLEDAEKEDSDEYQEQYIYYILEFPALIDAVNFV
QTVDYPVEESELYKVEQTYYMTVLINVAERSKQYPEYILSRMLEFTNDTKLTRPFLQEHGILMLGNGAIDELKKVQTV

Nucleotide


Download         Length: 717 bp        

>NTDB_id=559529 KEM15_RS08355 WP_130554705.1 1620519..1621235(-) (mecA) [Streptococcus parasuis strain NN1]
ATGAAAGTAAAACAAATAAGTGATTCGACTCTAAAAATCACTATCCAATTAGAAGATTTAGAGGAGCGCGGGATGGAAAT
TGCGGATTTCCTTATCCCTCAAGAAAAGACGGAAGAGTTTTTTTATACAGTATTGGATGAATTGGATTTGCCAATGACTT
TCCGAGAAAGTGGAATGCTTAGTTTTAGAGTTACTCCAAAACCGGATAAAGTGGATATTTTTGTCACAAAATCTGAAATG
GATCAAAGTTTAAATTTTGATGAATTTACAGATTTATCGGAATTAGGCGATGTATCAAGAATGACTCCAGATGAATTGCT
GAAAAGTTTGGAACGTACAGTTCGTGAACGAAGCACGCATGACTCAAAAGCAGTTCGTCTATTAGAAGATGCTGAAAAAG
AAGATAGTGATGAATACCAAGAACAGTATATTTACTATATCTTAGAATTTCCTGCTTTGATTGATGCGGTAAATTTTGTT
CAAACAGTGGATTATCCAGTTGAAGAATCTGAGCTCTACAAGGTGGAACAAACCTATTATATGACAGTATTGATTAATGT
TGCAGAGCGTTCAAAGCAGTATCCGGAGTATATTCTATCTCGCATGCTTGAATTTACAAATGATACCAAATTGACACGAC
CATTTCTTCAAGAGCACGGAATCTTGATGTTGGGAAATGGGGCCATTGATGAGTTGAAAAAGGTGCAAACGGTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

49.18

100

0.504
  mecA Streptococcus pneumoniae D39

49.18

100

0.504
  mecA Streptococcus pneumoniae R6

49.18

100

0.504
  mecA Streptococcus pneumoniae TIGR4

49.18

100

0.504
  mecA Streptococcus mutans UA159

47.951

100

0.492
  mecA Streptococcus thermophilus LMD-9

45.714

100

0.471
  mecA Streptococcus thermophilus LMG 18311

45.306

100

0.466