Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   KEM15_RS04780 Genome accession   NZ_CP073632
Coordinates   924452..925123 (+) Length   223 a.a.
NCBI ID   WP_130555646.1    Uniprot ID   A0A4Q8KZI7
Organism   Streptococcus parasuis strain NN1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 919452..930123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KEM15_RS04765 (KEM15_04680) - 919931..921832 (+) 1902 WP_274504851.1 LTA synthase family protein -
  KEM15_RS04770 (KEM15_04685) - 921829..923304 (+) 1476 WP_274504852.1 glucosyltransferase domain-containing protein -
  KEM15_RS04775 (KEM15_04690) - 923316..924248 (+) 933 WP_274504853.1 glycosyltransferase family 2 protein -
  KEM15_RS04780 (KEM15_04695) ciaR 924452..925123 (+) 672 WP_130555646.1 response regulator transcription factor Regulator
  KEM15_RS04785 (KEM15_04700) ciaH 925116..926489 (+) 1374 WP_274504854.1 HAMP domain-containing sensor histidine kinase Regulator
  KEM15_RS04790 (KEM15_04705) - 926576..927793 (+) 1218 WP_274504855.1 transglutaminase domain-containing protein -
  KEM15_RS04795 (KEM15_04710) rpsT 927827..928059 (-) 233 Protein_906 30S ribosomal protein S20 -
  KEM15_RS04800 (KEM15_04715) coaA 928090..929052 (-) 963 WP_274504856.1 type I pantothenate kinase -
  KEM15_RS04805 (KEM15_04720) - 929128..929718 (+) 591 WP_217375057.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25212.80 Da        Isoelectric Point: 4.2408

>NTDB_id=559512 KEM15_RS04780 WP_130555646.1 924452..925123(+) (ciaR) [Streptococcus parasuis strain NN1]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGIYEAETGVYDLILLDLMLPDKDGFQVLRELREKGVSTPVLITTA
KEGLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNTTTVNGQEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKVRKKLKGTAFGENLQTLRSVGYILKNV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=559512 KEM15_RS04780 WP_130555646.1 924452..925123(+) (ciaR) [Streptococcus parasuis strain NN1]
ATGATTAAAATATTATTGGTCGAAGATGATTTAAGTTTATCCAATTCAGTCTTTGATTTTTTAGATGATTTTGCAGACGT
TATGCAAGTTTTTGATGGTGAAGAAGGTATTTACGAAGCGGAAACAGGGGTTTATGATTTAATTCTTTTAGATTTAATGT
TACCTGATAAAGATGGTTTTCAAGTATTAAGAGAATTGCGTGAAAAAGGGGTCTCAACTCCTGTTCTGATTACGACAGCC
AAGGAAGGCCTAGAGGATAAAGGACATGGGTTTGAATTGGGTGCAGATGACTATCTCACAAAACCATTCTATTTAGAAGA
ACTCAAAATGCGTATTCAAGCCTTGTTAAAACGAGCAGGGAAGTTCAATGAAAATACTCTAACGTACGGAGATGTTACTG
TCGACTTATCTACAAATACTACGACAGTCAATGGTCAAGAAGTAGAATTGTTAGGGAAAGAATTCGACTTGTTGGTATAT
TTCTTACAGAACCAAAATGTGATTTTACCTAAAACACAGATTTTTGATCGTATTTGGGGATTTGATAGTGATACAACCAT
TTCAGTTGTTGAGGTTTACGTATCGAAAGTAAGGAAAAAATTGAAAGGAACTGCATTTGGAGAAAATCTTCAAACTCTTC
GTAGTGTCGGTTACATTTTGAAAAATGTCTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Q8KZI7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

88.341

100

0.883
  ciaR Streptococcus pneumoniae Rx1

87.892

100

0.879
  ciaR Streptococcus pneumoniae D39

87.892

100

0.879
  ciaR Streptococcus pneumoniae R6

87.892

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.892

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.611

100

0.381