Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   KEM15_RS04785 Genome accession   NZ_CP073632
Coordinates   925116..926489 (+) Length   457 a.a.
NCBI ID   WP_274504854.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NN1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 920116..931489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KEM15_RS04770 (KEM15_04685) - 921829..923304 (+) 1476 WP_274504852.1 glucosyltransferase domain-containing protein -
  KEM15_RS04775 (KEM15_04690) - 923316..924248 (+) 933 WP_274504853.1 glycosyltransferase family 2 protein -
  KEM15_RS04780 (KEM15_04695) ciaR 924452..925123 (+) 672 WP_130555646.1 response regulator transcription factor Regulator
  KEM15_RS04785 (KEM15_04700) ciaH 925116..926489 (+) 1374 WP_274504854.1 HAMP domain-containing sensor histidine kinase Regulator
  KEM15_RS04790 (KEM15_04705) - 926576..927793 (+) 1218 WP_274504855.1 transglutaminase domain-containing protein -
  KEM15_RS04795 (KEM15_04710) rpsT 927827..928059 (-) 233 Protein_906 30S ribosomal protein S20 -
  KEM15_RS04800 (KEM15_04715) coaA 928090..929052 (-) 963 WP_274504856.1 type I pantothenate kinase -
  KEM15_RS04805 (KEM15_04720) - 929128..929718 (+) 591 WP_217375057.1 class I SAM-dependent methyltransferase -
  KEM15_RS04810 (KEM15_04725) - 929715..930992 (+) 1278 WP_274504857.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 51499.73 Da        Isoelectric Point: 5.3829

>NTDB_id=559513 KEM15_RS04785 WP_274504854.1 925116..926489(+) (ciaH) [Streptococcus parasuis strain NN1]
MSKRFKKIISTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQTSDSTLARIKDAPALVVGFAIARTYEPNSEFIIQD
GNITDESDSAESNSYTPNSPKNQKDDQLKLGYNTHVLLYSNDGVVVNPDNFTGLSDLSLDKKNLGEIKEVTVDSTFGGSE
DYRYVTIELAPDDLGYYSSYDIKYATIFVNVSQIKSSIETYETAVAIVMVSAWLISILASIYLSNLSMRPILISYQKQKD
FVENASHELRTPLAVLQNRLEGLFRHPNATILESSESIGSSLEEVRNMRMLTTNLLNLARRDDGFKLDIVEVPPSYFDEI
FKNYMMIADENGKTVTVNNLIDQPIRTDKVLVKQLLTILFDNAMKYTEDDGAIQVTANIKDKLVYFTVADNGLGISDSDK
KKIFDRFYRVDKARTRSKGGFGLGLSLALQISNSLKGTITVRDNQPKGTIFEVRLPR

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=559513 KEM15_RS04785 WP_274504854.1 925116..926489(+) (ciaH) [Streptococcus parasuis strain NN1]
ATGTCTAAGCGATTTAAAAAAATCATTTCAACAGATAAATTTTCCTTTTTTATCAGATATTTTGCTGTTTTTACACTCAT
TTTCGGATTAATGACCGCCATTATCTTCCAGTTAATGCGCTCAACTATGTATCAGACTTCTGATTCAACACTGGCTCGTA
TCAAAGATGCCCCTGCTTTGGTGGTTGGTTTTGCCATTGCACGGACCTATGAACCAAATTCAGAATTCATTATTCAAGAT
GGAAATATTACTGATGAAAGTGATTCTGCAGAATCTAATTCATATACACCAAACTCCCCTAAAAATCAGAAAGACGATCA
GTTGAAACTTGGTTACAATACACATGTATTACTCTATTCAAATGATGGTGTAGTCGTTAATCCAGATAACTTTACAGGAC
TTTCTGATTTATCCTTAGACAAGAAAAATTTAGGCGAAATAAAGGAAGTAACGGTTGATTCTACATTCGGGGGTTCAGAA
GATTATCGTTATGTTACTATTGAATTGGCGCCAGATGACCTTGGCTATTATTCTTCCTATGATATTAAATACGCGACAAT
TTTCGTGAATGTGAGTCAGATAAAATCATCCATTGAGACGTATGAAACTGCTGTAGCTATTGTCATGGTATCTGCTTGGC
TTATTTCCATCTTGGCTAGTATTTATCTGTCAAATTTGAGTATGCGACCTATCTTAATTAGCTATCAAAAACAAAAGGAT
TTCGTTGAGAATGCTAGTCATGAATTGAGAACGCCTTTAGCTGTGTTACAGAATCGTTTGGAAGGTCTTTTTAGACATCC
AAATGCAACCATTCTGGAAAGTAGTGAGAGTATAGGATCAAGCCTAGAGGAAGTTCGTAATATGCGTATGTTAACTACGA
ATTTACTGAATTTAGCTCGTCGAGATGATGGTTTCAAATTAGATATAGTTGAAGTCCCACCTAGCTATTTTGATGAAATC
TTTAAGAATTACATGATGATTGCAGATGAAAATGGTAAAACAGTCACGGTTAATAATTTGATTGATCAACCAATTCGGAC
GGATAAGGTGTTGGTAAAACAGCTTCTAACCATCCTATTTGATAATGCAATGAAGTATACCGAAGATGATGGCGCTATAC
AAGTGACAGCCAATATCAAAGATAAGTTAGTTTACTTTACGGTAGCAGACAATGGATTGGGTATCAGTGATAGTGATAAA
AAGAAAATTTTCGATCGATTTTATCGTGTAGACAAGGCCCGTACTCGGAGCAAGGGTGGGTTTGGTCTCGGTTTATCTTT
AGCCTTACAAATTTCCAATAGTTTGAAAGGCACAATCACTGTGCGGGATAATCAGCCTAAAGGAACTATTTTTGAGGTAA
GATTACCGAGATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(238-304)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-456)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50.877

99.781

0.508
  ciaH Streptococcus pneumoniae D39

50.877

99.781

0.508
  ciaH Streptococcus pneumoniae R6

50.877

99.781

0.508
  ciaH Streptococcus pneumoniae TIGR4

50.877

99.781

0.508
  ciaH Streptococcus mutans UA159

50.331

99.125

0.499