Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   KCL43_RS08315 Genome accession   NZ_CP073275
Coordinates   1730023..1731918 (-) Length   631 a.a.
NCBI ID   WP_012677494.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain IN-6992     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1725023..1736918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KCL43_RS08290 (KCL43_08290) - 1725765..1726130 (-) 366 WP_042671180.1 S1 RNA-binding domain-containing protein -
  KCL43_RS08295 (KCL43_08295) - 1726130..1727530 (-) 1401 WP_165623524.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  KCL43_RS08300 (KCL43_08300) - 1727563..1728204 (-) 642 WP_041785672.1 response regulator transcription factor -
  KCL43_RS08305 (KCL43_08305) - 1728197..1729201 (-) 1005 WP_012516143.1 sensor histidine kinase -
  KCL43_RS08310 (KCL43_08310) liaF 1729198..1729890 (-) 693 WP_012679994.1 cell wall-active antibiotics response protein LiaF -
  KCL43_RS08315 (KCL43_08315) pknB 1730023..1731918 (-) 1896 WP_012677494.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  KCL43_RS08320 (KCL43_08320) - 1731915..1732655 (-) 741 WP_012516146.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KCL43_RS08325 (KCL43_08325) rsmB 1732693..1734015 (-) 1323 WP_165623528.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KCL43_RS08330 (KCL43_08330) fmt 1734005..1734940 (-) 936 WP_212573358.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 68568.74 Da        Isoelectric Point: 6.6073

>NTDB_id=558794 KCL43_RS08315 WP_012677494.1 1730023..1731918(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENPNVP
QALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYNRSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAADAR
LEQTSQMDTLQKPQKKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEAGLKVGKVH
QIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDYQDVMTSLTETYGVPKSKIKIERIVTNEYPE
NTVISQSPSAGEKFNPAGKSKITLSVAVGDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSS
KAIVSGQTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQNDAVTTP

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=558794 KCL43_RS08315 WP_012677494.1 1730023..1731918(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
ATGATTCAGATTGGCAAGCTATTTGCTGGTCGTTATCGCATTCTAAAATCTATAGGCCGCGGTGGTATGGCGGATGTTTA
TTTAGCAAACGATTTGATTCTGGATAATGAGGACGTTGCCATTAAGGTCTTGCGGACCAATTATCAAACAGATCAGGTTG
CTGTTGCGCGTTTTCAAAGAGAAGCGCGAGCCATGGCTGAATTAAATCACCCCAATATTGTTGCCATTCGGGATATAGGC
GAGGAAGACGGACAGCAATTTTTAGTAATGGAATATGTTGATGGCTCTGATTTGAAAAAATACATTCAGGATCATGCGCC
ATTATCTAACAATGAGGTGGTGAGAATCATGGAAGAGGTTCTTTCTGCCATGACTCTGGCCCACCAAAAAGGAATTGTTC
ACAGGGATTTAAAGCCTCAAAACATTCTTTTGACCAAATCAGGTGTTGTTAAGGTTACAGATTTTGGGATTGCCGTTGCC
TTTGCAGAGACCAGTCTAACCCAGACAAATTCTATGCTAGGAAGTGTGCATTACCTCTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACGATTCAAAGTGATATTTACGCGATGGGAATTATGCTCTTTGAAATGCTAACAGGGCATATTCCTTATGATG
GCGATAGCGCTGTGACGATTGCTCTGCAGCATTTTCAAAAGCCGCTGCCCTCTATCATTGATGAAAATCCTAATGTGCCT
CAAGCCTTGGAGAACGTCGTTATTCGGGCTACTGCCAAAAAGCTAAGTGACCGTTATCGCTCGACCTTTGAGATGAGCAG
GGATTTGATGACAGCCCTTAGCTATAACCGCAGTCGTGAGCGTAAGGTTGTCTTTGATGATGTCGAAAGCACAAAGCCCT
TGCCAAAGGTAACACCGACTCCTGTAACAGCACCTAAGGTATCAAATGCTAGTCAGGCATCTGCGGCAGCTGATGCTAGA
CTTGAGCAGACTAGCCAGATGGATACTCTGCAAAAGCCTCAAAAAAAGAAAAAAAATGGGCGTTTTCTAGGAACACTCTT
AAAAATCTTGTTTTCCTTTTTTGTTGTTGGTGTGGCTCTTTTTGCTTATTTGGTCTTGACCAAGCCAACTACGGTTAAGG
TTCCTGATGTGACAGGCTCTAGTCTCAATGCTGCCAAGCAGGTCTTGGAGGAGGCGGGACTAAAGGTCGGTAAGGTCCAT
CAGATTGAAAGTGACACAGTTAGTGAGGATCAGGTGGTTAAGACAAATCCTCAAGCTGGCTCAGCTAAGCGAAAAGGCTC
CAGCGTTGACCTTTATCTTTCGATCGGAAATAAAGGCTTTGAGATGGAAAATTATAAGGGACAGGATTATCAAGATGTGA
TGACCAGTCTGACTGAGACCTATGGCGTACCAAAGTCAAAAATCAAGATTGAGCGTATCGTGACAAATGAATACCCTGAA
AACACCGTTATTAGCCAGTCTCCAAGCGCAGGAGAAAAATTTAACCCAGCTGGTAAATCCAAGATTACGCTTAGTGTAGC
AGTGGGCGATACGGTCATCATGCCAATGGTAACTGAGTACAGCTATGCAGATGCGGTGAATACACTAACAGCCCTAGGAA
TTGATGCCGCAAGAATCAAGGCCTATGTACCAAGCTCCAGCTCTCCGACAGGCTTTGTGCAGGTGAGCTCCCCAAGCTCA
AAGGCGATTGTCAGTGGGCAGACACCGTATTATGGTACCCAGATTAGCCTTTCTGAAAAGGGTGATATTAGCCTCTACCT
CTACCCTGAGGAGACACGTGCATCAAGCAGCTCATCGAGCTCTGATACCTCGGCTCCTAATCCATCAGCTGGAGATACAA
CAGACTCAAGCAGTCATACCGAATTAGGTCAAAATGACGCTGTTACAACACCGTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(512-588)

PASTA domain (PASTA)

(441-506)

Protein kinase domain (Pkinase)

(12-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.714

94.295

0.62
  stkP/pknB Streptococcus salivarius strain HSISS4

62.415

93.185

0.582
  stkP Streptococcus pneumoniae TIGR4

57.558

81.775

0.471
  stkP Streptococcus pneumoniae D39

57.171

81.775

0.468
  stkP Streptococcus pneumoniae R6

57.171

81.775

0.468
  stkP Streptococcus pneumoniae Rx1

56.977

81.775

0.466