Detailed information NTG0558779

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: KCL43_RS05040
• Genome accession: NZ_CP073275
• Coordinates: 1055393..1056238 (+)
• Length: 281 a.a.
• NCBI ID: WP_012677974.1
• Uniprot ID: A0A6M1KS91
• Organism: Streptococcus equi subsp. zooepidemicus strain IN-6992
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1050393..1061238

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KCL43_RS05025 (KCL43_05025)	-	1052295..1052927 (+)	633	WP_165623381.1	ABC transporter ATP-binding protein	-
KCL43_RS05030 (KCL43_05030)	ylqF	1053520..1054374 (+)	855	WP_012677976.1	ribosome biogenesis GTPase YlqF	-
KCL43_RS05035 (KCL43_05035)	-	1054364..1055137 (+)	774	WP_043025839.1	ribonuclease HII	-
KCL43_RS05040 (KCL43_05040)	dprA	1055393..1056238 (+)	846	WP_012677974.1	DNA-processing protein DprA	Machinery gene
KCL43_RS05045 (KCL43_05045)	topA	1056345..1058477 (+)	2133	WP_165623382.1	type I DNA topoisomerase	-
KCL43_RS05050 (KCL43_05050)	-	1058592..1059239 (+)	648	WP_043030796.1	SatD family protein	-
KCL43_RS05055 (KCL43_05055)	-	1059260..1059973 (+)	714	WP_111690112.1	DUF3307 domain-containing protein	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 31330.23 Da
• Isoelectric Point: 8.8540

>NTDB_id=558779 KCL43_RS05040 WP_012677974.1 1055393..1056238(+) (dprA) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDIAVVSCCKNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYP
LALREIYNPPVLLFYQGDLSLLEKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVLVVEAKQRSGSLITCQLAMEEGR
DIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILSEYHYS

Nucleotide

• Length: 846 bp

>NTDB_id=558779 KCL43_RS05040 WP_012677974.1 1055393..1056238(+) (dprA) [Streptococcus equi subsp. zooepidemicus strain IN-6992]
ATGAACAATTTTGAACTTTATAAATTAAAAAAGGCTGGGCTGACTAATTTAAATATTCTTAACCTGATTGACTACCAGCA
GCGTAATAACAAGTCTCTATCCCTTAGAGATATAGCAGTGGTTTCTTGCTGCAAAAATCCAGTTTTATTTATTGAGACCT
ACAAGCAATTAAATGTCGCCTTGTTAAAAAAGGAATTCAATCAGTTTCCGAGCTTATCTATCCTAGATAAGCAATACCCA
TTGGCTCTGAGGGAAATCTACAATCCTCCTGTTTTACTCTTTTATCAAGGTGATTTAAGCCTGTTAGAAAAACCTAAGCT
GGCAGTCGTTGGCTCTAGAGAATCCAGTGAAATTGGGACGCGGTCTGTTTATAAAATCATTAAAGAGCTTAAGAATCACT
TTGTCATTGTCAGCGGGCTTGCTAGAGGTATTGATACCAGTGCTCATCTCGCTTGCTTGAAAGCAGGTGGGCAAACCATA
GCTGTTATCGGGACTGGCCTAGATCGCTACTATCCAAAGGAAAATCACCAGCTACAGGAGTTTTTATCTCAGCGTCATCT
CGTGCTCAGTGAATATGGGGCTGGAGAGGCCGCCTTGTCTTATCATTTCCCTGAAAGAAACCGTATTATCGCAGGTCTTA
GTCGAGGTGTCCTTGTTGTTGAGGCTAAGCAGCGCTCTGGCTCTTTGATTACCTGTCAGCTAGCTATGGAAGAGGGACGT
GATATTTTTGTCGTACCTGACAATATTCTTAATGGGACATCGGCGGGCTGTTTGAAGCTGATCAAAGATGGTGCCAGCTG
TGTCACTCATGGCAGAGACATTCTTTCAGAATACCACTATTCTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

3D structure

• AlphaFold DB: A0A6M1KS91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	68.571	99.644	0.683
dprA/cilB/dalA	Streptococcus mitis SK321	59.643	99.644	0.594
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	58.929	99.644	0.587
dprA	Lactococcus lactis subsp. cremoris KW2	56.584	100	0.566
dprA	Bacillus subtilis subsp. subtilis str. 168	42.4	88.968	0.377