Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   KCG54_RS11215 Genome accession   NZ_CP073115
Coordinates   2313078..2313365 (-) Length   95 a.a.
NCBI ID   WP_036472233.1    Uniprot ID   A0A4D7WS56
Organism   Neisseria subflava strain TT0077     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 2309538..2312108 2313078..2313365 flank 970


Gene organization within MGE regions


Location: 2309538..2313365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KCG54_RS11200 (KCG54_11210) - 2309538..2310545 (+) 1008 WP_254324202.1 IS5 family transposase -
  KCG54_RS11205 (KCG54_11215) - 2310996..2311991 (+) 996 Protein_2179 IS5 family transposase -
  KCG54_RS11210 (KCG54_11220) comP 2312399..2312893 (-) 495 WP_254324105.1 type IV pilin protein Machinery gene
  KCG54_RS11215 (KCG54_11225) comE 2313078..2313365 (-) 288 WP_036472233.1 helix-hairpin-helix domain-containing protein Machinery gene

Sequence

Protein


Download         Length: 95 a.a.        Molecular weight: 9763.42 Da        Isoelectric Point: 10.4923

>NTDB_id=558056 KCG54_RS11215 WP_036472233.1 2313078..2313365(-) (comE) [Neisseria subflava strain TT0077]
MKKFLFGAFAAVCAAFSLAAVNINTASSAELEALPGIGPAKAKSIVEYRQKNGAFKSVEELKNVKGIGDAVLNKLKAEAT
VSSAAPKAAQPAVKK

Nucleotide


Download         Length: 288 bp        

>NTDB_id=558056 KCG54_RS11215 WP_036472233.1 2313078..2313365(-) (comE) [Neisseria subflava strain TT0077]
ATGAAGAAATTTTTATTTGGTGCATTTGCCGCTGTTTGTGCAGCATTCTCTTTGGCCGCCGTGAACATCAATACCGCATC
TTCTGCCGAACTGGAGGCCTTGCCGGGTATCGGCCCGGCTAAGGCGAAATCGATTGTAGAATACCGCCAGAAGAACGGTG
CGTTCAAATCGGTGGAGGAGCTGAAAAACGTGAAGGGCATTGGTGATGCGGTGCTGAACAAGTTGAAGGCGGAGGCGACG
GTTTCTTCTGCCGCGCCTAAGGCTGCCCAGCCTGCCGTGAAAAAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(20-77)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4D7WS56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

62.626

100

0.653
  comE Neisseria gonorrhoeae MS11

62.626

100

0.653
  comE Neisseria gonorrhoeae MS11

62.626

100

0.653
  comE Neisseria gonorrhoeae MS11

62.626

100

0.653
  Cj0011c Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

54.321

85.263

0.463
  comEA Vibrio parahaemolyticus RIMD 2210633

44.186

90.526

0.4