Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   INT76_RS07235 Genome accession   NZ_CP073084
Coordinates   1397222..1398424 (-) Length   400 a.a.
NCBI ID   WP_212573042.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1392222..1403424
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS07210 (INT76_07210) - 1392619..1393134 (-) 516 WP_212569799.1 RDD family protein -
  INT76_RS07215 (INT76_07215) - 1393284..1393475 (-) 192 WP_212569800.1 DUF951 family protein -
  INT76_RS07220 (INT76_07220) dnaN 1393536..1394672 (-) 1137 WP_212569801.1 DNA polymerase III subunit beta -
  INT76_RS07225 (INT76_07225) dnaA 1394826..1396193 (-) 1368 WP_212569802.1 chromosomal replication initiator protein DnaA -
  INT76_RS07230 (INT76_07230) spo0J 1396396..1397157 (-) 762 WP_212569803.1 ParB/RepB/Spo0J family partition protein Regulator
  INT76_RS07235 (INT76_07235) htrA 1397222..1398424 (-) 1203 WP_212573042.1 S1C family serine protease Regulator
  INT76_RS07240 (INT76_07240) rlmH 1398599..1399078 (+) 480 WP_212569804.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  INT76_RS07245 (INT76_07245) - 1399104..1399769 (+) 666 WP_212569805.1 YoaK family protein -
  INT76_RS07265 (INT76_07265) - 1400184..1402766 (-) 2583 WP_212569806.1 YfhO family protein -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 41755.52 Da        Isoelectric Point: 4.3008

>NTDB_id=557859 INT76_RS07235 WP_212573042.1 1397222..1398424(-) (htrA) [Streptococcus oriscaviae strain HKU75]
MGKESYMKKYLKFAILFVVGFVGGLAGALVAPLFQTSNSIPQTQSSTGSTTVSNVQYDNETSTTKAVEKVQNAVVSVVNY
QQASNNLTSIFGNTESSDELAVAGEGSGVIYKKEGDTAYIVTNTHVITGAEKIDILLASGEKVEGELVGSDTYSDLAVIK
IAAEKVTTVAEFADSNSINVGETAIAIGSPLGSVYANSVTQGIVSSLSRTVTSRSDDGQTISTNAIQTDTAINPGNSGGP
LINIQGQVIGINSSKITSSSNSNSSIAVEGMGFAIPSNDVVTIINQLETDGKVIRPALGVHMVNLTDLSTSQLEKAGLAD
SDLTSGVLIVSTQAGLPADGKFEPYDVITAIDGETIETKSDLQSALYNHKVGDTIEITFYRKGEKKTISIQLTHSTDELS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=557859 INT76_RS07235 WP_212573042.1 1397222..1398424(-) (htrA) [Streptococcus oriscaviae strain HKU75]
ATAGGAAAGGAAAGTTATATGAAAAAATATTTGAAATTTGCTATCTTATTTGTCGTTGGTTTCGTTGGTGGACTTGCAGG
AGCGCTTGTTGCCCCTTTGTTTCAAACGTCTAATTCCATACCACAAACACAAAGTTCAACAGGTTCTACAACCGTCAGCA
ATGTTCAGTATGACAATGAAACTTCCACCACAAAAGCTGTGGAAAAAGTTCAAAATGCCGTTGTGTCCGTTGTAAATTAT
CAGCAGGCCAGCAATAATCTAACATCTATCTTTGGTAACACAGAAAGTTCAGATGAGTTAGCAGTAGCAGGAGAAGGTTC
AGGTGTTATTTATAAGAAAGAAGGCGACACAGCCTACATTGTAACCAATACACACGTCATTACCGGTGCTGAAAAAATTG
ACATCTTATTGGCTTCTGGGGAAAAAGTAGAGGGTGAATTAGTAGGTTCAGACACTTATTCTGACCTAGCAGTCATTAAA
ATTGCTGCAGAAAAGGTGACAACAGTCGCTGAATTTGCAGATTCCAACTCCATCAATGTAGGAGAAACAGCCATCGCTAT
CGGAAGTCCTCTAGGAAGTGTTTATGCCAATTCGGTAACCCAAGGTATCGTTTCAAGTCTTAGTCGGACTGTAACCTCTC
GTTCTGATGATGGTCAGACTATTTCCACCAACGCTATCCAAACAGATACAGCTATCAACCCAGGAAACTCAGGCGGGCCT
CTTATCAACATTCAAGGTCAGGTTATTGGTATTAACTCTAGCAAGATTACTTCCAGCTCTAATAGTAACTCTAGCATAGC
AGTTGAGGGGATGGGATTTGCTATTCCATCAAATGATGTTGTCACTATTATCAACCAACTGGAAACTGACGGTAAAGTCA
TTCGACCAGCTTTAGGTGTTCATATGGTCAACTTGACAGACCTATCAACCAGTCAATTAGAAAAAGCTGGATTAGCAGAT
AGTGACCTAACTTCTGGTGTCTTGATTGTTTCTACTCAAGCTGGATTGCCAGCAGATGGTAAATTTGAACCTTATGATGT
AATCACAGCCATTGACGGAGAAACGATTGAAACGAAGAGTGATCTTCAAAGTGCGCTCTATAACCACAAGGTAGGCGATA
CAATTGAAATTACATTCTATCGTAAAGGAGAAAAGAAAACCATCTCTATCCAACTAACCCATTCAACAGATGAATTGTCT
TGA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(106-251)

PDZ domain (PDZ_2)

(296-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

61.209

99.25

0.607
  htrA Streptococcus gordonii str. Challis substr. CH1

59.194

99.25

0.588
  htrA Streptococcus mitis NCTC 12261

56.079

100

0.565
  htrA Streptococcus pneumoniae TIGR4

55.779

99.5

0.555
  htrA Streptococcus pneumoniae D39

55.779

99.5

0.555
  htrA Streptococcus pneumoniae Rx1

55.779

99.5

0.555
  htrA Streptococcus pneumoniae R6

55.779

99.5

0.555