Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   INT76_RS05430 Genome accession   NZ_CP073084
Coordinates   1070820..1071536 (-) Length   238 a.a.
NCBI ID   WP_212572956.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1065820..1076536
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS05405 (INT76_05405) sufU 1065839..1066282 (-) 444 WP_212572951.1 Fe-S cluster assembly sulfur transfer protein SufU -
  INT76_RS05410 (INT76_05410) - 1066269..1067501 (-) 1233 WP_212572952.1 cysteine desulfurase -
  INT76_RS05415 (INT76_05415) sufD 1067503..1068765 (-) 1263 WP_212572953.1 Fe-S cluster assembly protein SufD -
  INT76_RS05420 (INT76_05420) sufC 1068783..1069559 (-) 777 WP_212572954.1 Fe-S cluster assembly ATPase SufC -
  INT76_RS05425 (INT76_05425) - 1069645..1070823 (-) 1179 WP_212572955.1 MraY family glycosyltransferase -
  INT76_RS05430 (INT76_05430) mecA 1070820..1071536 (-) 717 WP_212572956.1 adaptor protein MecA Regulator
  INT76_RS05435 (INT76_05435) - 1071719..1072558 (-) 840 WP_212572957.1 undecaprenyl-diphosphate phosphatase -
  INT76_RS05440 (INT76_05440) - 1072683..1074260 (+) 1578 WP_212572958.1 ABC transporter substrate-binding protein/permease -
  INT76_RS05445 (INT76_05445) - 1074253..1074993 (+) 741 WP_212572959.1 amino acid ABC transporter ATP-binding protein -
  INT76_RS05450 (INT76_05450) - 1075157..1075366 (-) 210 WP_075098784.1 hypothetical protein -
  INT76_RS05455 (INT76_05455) - 1075452..1076351 (-) 900 WP_212572960.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27765.47 Da        Isoelectric Point: 4.1288

>NTDB_id=557841 INT76_RS05430 WP_212572956.1 1070820..1071536(-) (mecA) [Streptococcus oriscaviae strain HKU75]
MKMKQISDSTLKITIKLEDLEERGMEIADFLVPQEKTEEFFYTVLDELELPLTFRESGMLSFRVTPKPDKVDIFVTKSDI
DKNLNFEDFADLANLEDLSQMTPDEFLKTLEKTVREKSAGDDAAVRYLEKVEAEEEEEIDDRYIYYILDFASLREVVAFV
DTVDYDVEESELYKMNGRYYMTVLINIENRTKNYLEYVLSRMLEYTNDTTISRPVLQEHGHILLPLAAIQELGKVSLS

Nucleotide


Download         Length: 717 bp        

>NTDB_id=557841 INT76_RS05430 WP_212572956.1 1070820..1071536(-) (mecA) [Streptococcus oriscaviae strain HKU75]
ATGAAAATGAAACAAATCAGTGATTCAACATTGAAAATCACAATAAAATTAGAAGATCTAGAAGAAAGAGGGATGGAAAT
CGCAGATTTTCTGGTTCCTCAAGAAAAGACGGAGGAGTTTTTCTACACAGTCTTAGATGAGCTAGAACTTCCCTTAACCT
TTCGAGAAAGCGGAATGCTTAGTTTTCGGGTGACTCCAAAGCCAGACAAGGTGGATATTTTTGTTACCAAATCAGACATT
GACAAAAACTTGAATTTTGAAGATTTTGCTGACTTGGCTAACTTAGAAGACCTGTCGCAAATGACACCTGATGAATTTTT
AAAGACCTTGGAGAAAACCGTCCGAGAAAAAAGTGCGGGCGATGACGCGGCTGTTCGTTATTTGGAAAAGGTCGAGGCAG
AAGAAGAGGAAGAGATTGACGACCGCTATATCTACTATATCTTGGATTTCGCTAGTTTGAGAGAAGTCGTGGCTTTTGTT
GATACGGTTGACTACGATGTGGAGGAATCTGAACTTTACAAGATGAACGGCCGCTACTATATGACCGTTCTTATCAACAT
CGAAAACCGCACAAAGAACTATCTGGAATATGTCCTATCTCGCATGTTGGAATACACCAACGACACAACGATTTCAAGAC
CTGTCTTGCAGGAACATGGTCATATCCTTTTGCCACTTGCGGCTATTCAAGAATTGGGAAAGGTTAGTCTTTCATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

59.592

100

0.613
  mecA Streptococcus pneumoniae D39

59.592

100

0.613
  mecA Streptococcus pneumoniae R6

59.592

100

0.613
  mecA Streptococcus pneumoniae TIGR4

59.184

100

0.609
  mecA Streptococcus mutans UA159

52.245

100

0.538
  mecA Streptococcus thermophilus LMD-9

47.244

100

0.504
  mecA Streptococcus thermophilus LMG 18311

46.85

100

0.5