Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   INT76_RS04395 Genome accession   NZ_CP073084
Coordinates   869107..871083 (-) Length   658 a.a.
NCBI ID   WP_212572594.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 864107..876083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS04370 (INT76_04370) - 864849..865217 (-) 369 WP_212572586.1 S1 RNA-binding domain-containing protein -
  INT76_RS04375 (INT76_04375) - 865224..866624 (-) 1401 WP_212572588.1 Cof-type HAD-IIB family hydrolase -
  INT76_RS04380 (INT76_04380) - 866656..867297 (-) 642 WP_212572590.1 response regulator transcription factor -
  INT76_RS04385 (INT76_04385) - 867269..868285 (-) 1017 WP_212573016.1 sensor histidine kinase -
  INT76_RS04390 (INT76_04390) liaF 868285..868980 (-) 696 WP_212572592.1 cell wall-active antibiotics response protein LiaF -
  INT76_RS04395 (INT76_04395) stkP 869107..871083 (-) 1977 WP_212572594.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  INT76_RS04400 (INT76_04400) - 871083..871820 (-) 738 WP_212572596.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  INT76_RS04405 (INT76_04405) rsmB 871859..873172 (-) 1314 WP_212572598.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  INT76_RS04410 (INT76_04410) fmt 873162..874097 (-) 936 WP_212572600.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 658 a.a.        Molecular weight: 70753.10 Da        Isoelectric Point: 6.0760

>NTDB_id=557836 INT76_RS04395 WP_212572594.1 869107..871083(-) (stkP) [Streptococcus oriscaviae strain HKU75]
MIQIGKIFAGRYRIVRQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDQIAIQRFQREARAMADLDHPNIVRISDIG
EEDGQQYLAMEYVDGLDLKRYIKENAPLSNDTSVRIMGQILLAMRMAHTRGIVHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIILFEMLTGRIPYDGDSAVTIALQHFQKPLPSVRDENPRVP
QALENVVLKATAKKLTERYKTVAEMYTDLASALSLDRRHEPRVVLEGNKVDTKTLPKLSQAAVEPKRPAATPSNKDEAVG
ARPEVSASVNKPTKPKRRMRMRYKVLIGATLLTIIGFLIVLYNTPATVTVPDVRGQTLEVAKEKIETSGLKVGTVTEEES
SDVEEGTVLRTNPAANSSKREGSTVDIVLASAEAVTVPDVVGQDASVAQQELENAGFTVKRKEEYSDSVESGTVIKTDPI
AESSKAKGSSVTIVVSKGPQPTTVPDVVGKSQEVASQELKTAGFLVGDITQEYSDTLAEGVVISTNPTVGSSLTKGSTVN
LIVSKGPAITMPDFGVMKYSYAEARRQLQNLGVSVSTIEKQEDSSYAATTSDLVVGQYPAAGSTIDGTVTLYVSVASNSQ
QGGSSSSSSTGTSSSNGQ

Nucleotide


Download         Length: 1977 bp        

>NTDB_id=557836 INT76_RS04395 WP_212572594.1 869107..871083(-) (stkP) [Streptococcus oriscaviae strain HKU75]
ATGATACAGATTGGAAAGATCTTTGCAGGTCGCTACCGGATCGTTCGACAGATTGGTCGCGGTGGTATGGCAGATGTCTA
TCTAGCCCGCGACCTGATTTTAGATGGTGAAGAGGTCGCCGTGAAGGTCCTTCGGACCAACTATCAGACGGATCAGATTG
CCATTCAACGCTTCCAGAGAGAGGCTCGCGCGATGGCTGACCTAGACCATCCTAACATTGTTCGTATCTCAGACATTGGA
GAAGAAGATGGTCAGCAGTATTTGGCCATGGAGTATGTAGACGGTCTTGACCTGAAACGATACATCAAAGAAAATGCTCC
TCTATCCAATGACACTTCTGTCCGTATCATGGGGCAAATTCTCCTTGCCATGCGGATGGCCCATACTAGGGGAATTGTTC
ACCGGGATTTAAAACCTCAAAACGTTCTGTTAACCAAAGACGGAACGGCCAAGGTGACAGATTTCGGTATCGCGGTTGCC
TTTGCTGAAACCAGCCTAACCCAGACCAATTCAATGCTCGGCTCGGTTCATTACCTATCACCTGAACAGGCGCGGGGGTC
TAAGGCGACTGTGCAAAGTGATATTTATGCCATGGGGATTATCCTCTTTGAGATGCTGACAGGTCGTATTCCCTACGATG
GGGATAGTGCTGTAACCATCGCCCTCCAGCATTTCCAAAAACCGCTTCCGTCAGTTAGAGATGAAAATCCAAGAGTGCCA
CAAGCATTGGAAAATGTGGTCCTCAAGGCTACCGCCAAGAAGTTGACAGAGCGCTATAAGACAGTTGCTGAAATGTATAC
TGACTTGGCGTCAGCCCTGTCCTTGGATCGTCGGCATGAACCGCGTGTTGTCCTGGAGGGAAATAAGGTCGACACCAAAA
CTCTCCCTAAATTATCTCAGGCTGCTGTGGAGCCTAAACGGCCAGCAGCCACCCCATCTAATAAGGATGAGGCAGTAGGG
GCTCGACCAGAGGTGTCAGCGTCGGTCAATAAACCAACCAAGCCCAAGCGCCGGATGCGTATGCGCTACAAGGTGTTAAT
TGGTGCGACACTTTTGACCATCATTGGATTCTTGATTGTACTCTATAACACTCCAGCAACGGTTACGGTTCCAGATGTCA
GAGGGCAAACCTTGGAAGTTGCTAAGGAAAAAATAGAAACATCAGGTTTGAAAGTGGGAACGGTAACAGAGGAGGAGTCC
TCCGATGTGGAAGAAGGAACTGTTCTTCGGACCAATCCAGCAGCCAACAGCTCCAAGCGTGAAGGCAGTACAGTAGATAT
TGTTCTAGCCTCTGCAGAAGCAGTCACAGTTCCAGATGTGGTTGGCCAAGATGCTTCCGTGGCACAACAGGAATTAGAAA
ATGCTGGTTTTACCGTCAAGCGCAAGGAAGAATACAGTGACAGCGTAGAGAGCGGAACGGTTATTAAGACCGATCCAATA
GCTGAAAGCTCCAAGGCCAAAGGCAGTTCGGTTACGATTGTTGTTTCCAAAGGCCCACAACCAACGACAGTTCCAGATGT
GGTCGGTAAGAGTCAGGAAGTAGCTAGTCAGGAGTTGAAAACTGCCGGTTTCCTAGTAGGTGATATCACACAAGAGTACA
GCGATACCCTTGCAGAGGGAGTGGTAATCAGTACCAATCCTACGGTAGGAAGTAGCTTGACTAAGGGCTCCACTGTCAAC
CTAATCGTGTCAAAAGGACCGGCTATTACCATGCCAGATTTTGGTGTGATGAAGTATAGTTATGCAGAAGCAAGACGTCA
GCTTCAAAACTTGGGAGTGTCAGTTTCTACTATTGAGAAACAAGAAGATAGCAGTTACGCGGCTACAACCAGTGACCTGG
TTGTAGGACAGTACCCAGCAGCTGGCAGCACGATTGATGGAACGGTGACTCTCTATGTTTCCGTTGCCTCCAATTCACAG
CAAGGAGGAAGCTCTAGTTCTTCTTCCACTGGTACCTCTTCCAGCAACGGTCAATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(503-565)

PASTA domain (PASTA)

(435-497)

PASTA domain (PASTA)

(368-430)

PASTA domain (PASTA)

(570-634)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

53.858

98.48

0.53
  stkP Streptococcus pneumoniae D39

53.549

98.48

0.527
  stkP Streptococcus pneumoniae R6

53.549

98.48

0.527
  stkP Streptococcus pneumoniae Rx1

53.395

98.48

0.526
  stkP/pknB Streptococcus salivarius strain HSISS4

55.963

82.827

0.464
  pknB Streptococcus mutans UA159

61.837

74.468

0.46