Detailed information NTG0557828

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: INT76_RS03275
• Genome accession: NZ_CP073084
• Coordinates: 669848..672088 (-)
• Length: 746 a.a.
• NCBI ID: WP_212572146.1
• Uniprot ID: -
• Organism: Streptococcus oriscaviae strain HKU75
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 664848..677088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INT76_RS03255 (INT76_03255)	-	664973..666268 (-)	1296	WP_212572138.1	poly(R)-hydroxyalkanoic acid synthase subunit PhaE	-
INT76_RS11155 (INT76_03260)	-	666500..667900 (-)	1401	WP_212572140.1	InlB B-repeat-containing protein	-
INT76_RS03265 (INT76_03265)	-	668330..668998 (-)	669	WP_212572142.1	recombinase family protein	-
INT76_RS03270 (INT76_03270)	-	669138..669767 (-)	630	WP_212572144.1	Maf family protein	-
INT76_RS03275 (INT76_03275)	comEC/celB	669848..672088 (-)	2241	WP_212572146.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
INT76_RS03280 (INT76_03280)	comEA/celA/cilE	672072..672719 (-)	648	WP_212572153.1	helix-hairpin-helix domain-containing protein	Machinery gene
INT76_RS03285 (INT76_03285)	-	672778..673521 (-)	744	WP_212572155.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
INT76_RS03290 (INT76_03290)	-	673621..674370 (+)	750	WP_212572156.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
INT76_RS03295 (INT76_03295)	-	674360..674647 (+)	288	WP_212572158.1	GIY-YIG nuclease family protein	-
INT76_RS03300 (INT76_03300)	-	674693..674917 (+)	225	WP_212572160.1	hypothetical protein	-
INT76_RS03305 (INT76_03305)	-	674997..675197 (-)	201	WP_212572161.1	hypothetical protein	-
INT76_RS03310 (INT76_03310)	-	675322..676380 (-)	1059	WP_212572163.1	LLM class flavin-dependent oxidoreductase	-
INT76_RS03315 (INT76_03315)	-	676494..676904 (-)	411	WP_212572165.1	hypothetical protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84662.56 Da
• Isoelectric Point: 6.7330

>NTDB_id=557828 INT76_RS03275 WP_212572146.1 669848..672088(-) (comEC/celB) [Streptococcus oriscaviae strain HKU75]
MSQWIKRLSLPPIQLAILLLVVYFTIHSFSFLTMGLLSLFLLALFLGQKRQVFLKVLPLLCLFSLFVCFQRLQWQEEDQS
APTHLDRVHLLPDTIQIKGDSLSFRGRADGRLYQVFYQLASQEEQAYFYSLSDTVEIEVEAVVGEATGQRNFNGFDYQAY
LASQGIYRTVTIKTMKEVTAVNSWNPFDWLSSLRKKTIDHIRTHFPAPMSHYMTGLLFGELGSEFEQMSAIYSSLGIIHL
FALSGMQVGFFVDRFRWLFMRLGLTKEWVDWLQYPFSFVYAGLTGFSVSVVRSLIQKLLANHGVKKLDNLALTILICLFF
LPRSLMTAGGILSFSYAFLLGVFDFEELPRWRKLAAESLSISLGILPLLMTHFYSFQPLSILLTFLFSFIFDFLLLPGLS
VIFLLSPVLKIDWVNGLFVCLEEVILWVANLGFRPLILGKPSDFLLLCLVLVLLLIHDFRRKKRCLFALSLLLALLFFMV
KHPLENEVTMVDIGQGDSLFLRDVSGRTVLIDVGGRLEFASKEGWRKRSRESNAQQTLIPYLHSRGVGRIDSLVLTHTDT
DHVGDVLEVAKHVEIGEVYVSPGSLTVPDFVATLKQLNVPVHVAEVGDKIPIMGSHLEVLYPAETGDGGNNDSIVLYGRL
LGTNFLFTGDLEQGELDLIENYPNLPVDVLKAGHHGSKGSSYPEFLEHIDAKIALVSAGVNNRYKHPHQETLARFEEQQM
QVYRTDQQGAVRFRGWSSWRIETVRE

Nucleotide

• Length: 2241 bp

>NTDB_id=557828 INT76_RS03275 WP_212572146.1 669848..672088(-) (comEC/celB) [Streptococcus oriscaviae strain HKU75]
ATGTCACAGTGGATTAAGCGCCTCTCTCTGCCACCCATTCAGCTGGCGATTCTTTTGTTGGTTGTCTATTTCACCATTCA
TTCGTTTTCTTTTTTGACAATGGGCCTTCTCAGTTTGTTTCTTCTGGCTCTTTTTCTTGGTCAAAAAAGACAGGTTTTTC
TAAAGGTGCTGCCGCTACTCTGTTTGTTTAGTCTGTTTGTCTGCTTTCAGCGGCTGCAATGGCAAGAGGAAGACCAGTCA
GCTCCGACCCACTTGGACAGGGTACATCTGCTACCGGATACTATCCAAATAAAGGGGGATAGTCTGTCTTTTCGAGGCAG
GGCTGACGGTCGGCTCTATCAGGTCTTTTATCAATTGGCCAGTCAGGAGGAACAGGCTTATTTCTACTCTCTATCAGATA
CGGTGGAGATAGAGGTTGAAGCGGTGGTCGGTGAGGCAACAGGTCAACGAAATTTTAATGGTTTTGATTATCAGGCCTAT
CTGGCCAGTCAGGGCATTTATCGTACGGTGACCATTAAGACGATGAAGGAGGTAACGGCTGTCAACAGTTGGAATCCCTT
TGACTGGCTGTCTAGTCTGCGAAAAAAGACGATCGATCATATTAGAACCCATTTTCCAGCACCCATGAGCCATTATATGA
CGGGGCTGTTGTTTGGGGAATTGGGGAGTGAGTTTGAACAGATGAGCGCCATTTATTCGAGTCTGGGGATCATCCATCTC
TTTGCTCTGTCTGGCATGCAGGTCGGCTTTTTTGTAGACCGATTTCGCTGGCTGTTCATGCGCCTGGGTCTGACCAAGGA
GTGGGTGGATTGGTTACAGTATCCTTTTTCCTTTGTCTACGCGGGTCTGACTGGCTTTTCAGTATCGGTAGTTCGCTCGC
TTATACAGAAATTATTAGCGAATCACGGTGTGAAAAAGTTGGACAATCTTGCTTTGACCATCTTGATTTGTCTGTTTTTT
CTTCCTAGATCGTTGATGACGGCTGGAGGGATTTTGAGTTTTTCCTATGCCTTTTTGTTGGGGGTGTTCGATTTTGAAGA
GTTGCCTCGGTGGAGGAAACTTGCGGCGGAGAGTTTGAGTATCTCGTTGGGGATTTTACCGCTTCTGATGACCCATTTTT
ATTCGTTCCAGCCTCTTTCTATCCTCTTGACCTTTCTTTTTTCTTTCATTTTTGATTTCTTGCTACTGCCAGGTCTGTCG
GTCATTTTTCTCTTATCACCTGTGCTGAAGATAGATTGGGTCAACGGTTTATTTGTTTGTTTGGAGGAGGTCATTCTTTG
GGTGGCCAATCTGGGCTTTAGGCCCTTGATACTGGGAAAACCGTCAGATTTTCTCCTCTTGTGTCTAGTTCTTGTCTTGC
TTCTGATTCATGATTTTCGCAGGAAAAAGCGGTGTTTGTTCGCCCTGAGTCTCTTGCTCGCTCTGCTTTTTTTCATGGTA
AAACATCCCTTGGAAAACGAGGTGACCATGGTGGATATCGGTCAGGGGGATAGTCTGTTCTTGAGGGATGTGTCGGGGCG
AACTGTTCTGATTGATGTGGGTGGACGCCTTGAGTTTGCAAGTAAGGAAGGCTGGCGAAAACGGTCGCGGGAAAGCAATG
CCCAGCAAACCCTGATTCCCTATCTCCACAGTCGAGGGGTGGGGCGGATTGATTCGTTGGTTCTGACCCACACCGACACG
GACCATGTGGGCGATGTGCTGGAGGTGGCCAAGCATGTCGAAATTGGAGAGGTGTATGTGTCGCCAGGAAGTTTGACCGT
TCCAGACTTTGTGGCAACTCTGAAGCAGCTCAATGTTCCAGTCCATGTGGCAGAGGTAGGTGATAAGATTCCCATCATGG
GTTCTCACTTGGAGGTTCTTTATCCAGCAGAAACTGGTGATGGGGGCAATAATGATTCCATTGTTCTTTATGGTCGCTTG
CTGGGAACCAACTTCCTCTTTACAGGGGATTTGGAGCAGGGAGAGCTCGACTTGATAGAAAACTATCCAAATCTGCCGGT
CGATGTACTCAAGGCCGGGCACCATGGTTCCAAAGGTTCTTCTTACCCTGAGTTTTTGGAACATATTGACGCTAAGATTG
CCTTGGTATCGGCTGGTGTCAACAATCGCTACAAACACCCTCATCAAGAAACCTTGGCTCGTTTTGAAGAGCAGCAGATG
CAGGTCTATCGGACAGACCAGCAAGGCGCTGTCCGTTTTAGAGGCTGGTCAAGCTGGCGCATAGAAACAGTAAGAGAATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-174)

• Competence protein (Competence) (216-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.949	100	0.529
comEC/celB	Streptococcus mitis SK321	52.878	100	0.529
comEC/celB	Streptococcus pneumoniae TIGR4	51.807	100	0.519
comEC/celB	Streptococcus pneumoniae Rx1	51.539	100	0.516
comEC/celB	Streptococcus pneumoniae D39	51.539	100	0.516
comEC/celB	Streptococcus pneumoniae R6	51.539	100	0.516
comEC	Lactococcus lactis subsp. cremoris KW2	47.177	99.732	0.471