Detailed information NTG0557131

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: KBW87_RS02045
• Genome accession: NZ_CP072983
• Coordinates: 392494..394656 (+)
• Length: 720 a.a.
• NCBI ID: WP_057809199.1
• Uniprot ID: -
• Organism: Lactobacillus intestinalis strain DSM 6629
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 387494..399656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KBW87_RS02015 (KBW87_02010)	-	387869..388855 (+)	987	WP_057809208.1	class III bacteriocin	-
KBW87_RS02020	-	389010..389588 (+)	579	WP_057809205.1	garvicin Q family class II bacteriocin	-
KBW87_RS02025 (KBW87_02020)	-	389610..389927 (+)	318	WP_057809203.1	bacteriocin immunity protein	-
KBW87_RS02030 (KBW87_02025)	-	390100..390273 (+)	174	WP_157055113.1	hypothetical protein	-
KBW87_RS02035 (KBW87_02030)	-	390284..391684 (+)	1401	WP_201779824.1	sensor histidine kinase	-
KBW87_RS02040 (KBW87_02035)	-	391688..392497 (+)	810	WP_057809201.1	LytTR family DNA-binding domain-containing protein	-
KBW87_RS02045 (KBW87_02040)	comA	392494..394656 (+)	2163	WP_057809199.1	peptide cleavage/export ABC transporter	Regulator
KBW87_RS02050 (KBW87_02045)	-	394668..395306 (+)	639	WP_057809197.1	HlyD family efflux transporter periplasmic adaptor subunit	-
KBW87_RS02055 (KBW87_02050)	-	395522..395674 (+)	153	WP_157055112.1	hypothetical protein	-
KBW87_RS02060 (KBW87_02055)	-	395700..395861 (+)	162	WP_157055111.1	bacteriocin	-
KBW87_RS02065 (KBW87_02060)	-	396042..396209 (+)	168	WP_157055110.1	hypothetical protein	-
KBW87_RS02070 (KBW87_02065)	-	396223..397029 (+)	807	WP_057809195.1	CPBP family intramembrane glutamic endopeptidase	-
KBW87_RS02075 (KBW87_02070)	-	397192..399093 (+)	1902	WP_057809194.1	heavy metal translocating P-type ATPase	-
KBW87_RS02080 (KBW87_02075)	-	399113..399343 (+)	231	WP_057809192.1	heavy-metal-associated domain-containing protein	-

Sequence

Protein

• Length: 720 a.a.
• Molecular weight: 81093.29 Da
• Isoelectric Point: 9.7387

>NTDB_id=557131 KBW87_RS02045 WP_057809199.1 392494..394656(+) (comA) [Lactobacillus intestinalis strain DSM 6629]
MNIFKYRSIYIPQVDETDCGAACLAMILKYYHSRISIAHLRHIAKTNTEGTTAFGLVKTAESFNMEVQAVKADMSLFNME
DIQYPFIVHVVKEGSLLHYYVVLKSTKNKIVIADPDPTSGIKKISKKAFEKEWTGVTLLMIPKSNFKVIKEKKTNLISLL
PYLFKQKTLIKNIILATILVTLISIGTSYFVQGLIDTYIPNEAYTILSILAIGLLIAYVFNSIFQYGQQVLLNILGQRLS
IDLNLQYIRHVFELPMEFFTTRKTGEITSRFSDASRIIDALARMVISLFLALSIVILMGIVLALQNMTLFLITLFSIPIY
AIIILGFTKKFEKLNNDQMESNAVVSSSIIEDIQGIETIKALNSEQIRYRKIDEQFVDYLRKAFKYSKNETLQTVLKTFV
RLALNIVVLWVGAIIVMHNQMSIGQLMAFNALLAYFVDPLQNIINLQPTLQAANVAQNRLNEVYLVKSEFNKTASINKIQ
QIEGDIHLTHVYYRYGYGSDVLQNISLKISPGEKLTIVGMSGSGKSTLVKLLVAFYSPTKGKLTFNNKAVSNIDKHILRS
YVNYVPQIPCVFSGTIKENLLLGSRPHISDEEIKKACQIAEIKDDIEKLPLQYDTPLDENAKVLSGGQKQRLTIARALLT
PAKVLILDEATSGLDTITEKKVVNNLLQLKDKTIIFIAHRLSIAKKTDNIIVLSKGQIVEHGSHKELMAAQGYYYNLVKS

Nucleotide

• Length: 2163 bp

>NTDB_id=557131 KBW87_RS02045 WP_057809199.1 392494..394656(+) (comA) [Lactobacillus intestinalis strain DSM 6629]
ATGAATATTTTCAAATATAGGTCAATCTATATTCCGCAAGTTGATGAAACCGACTGTGGAGCTGCCTGTTTAGCAATGAT
TTTAAAATATTATCATTCACGAATTTCTATAGCTCATTTAAGACATATCGCTAAAACTAATACTGAAGGTACGACGGCTT
TTGGACTAGTTAAGACTGCTGAAAGTTTTAATATGGAGGTACAAGCAGTAAAGGCAGATATGTCTTTATTTAATATGGAA
GACATTCAATATCCCTTTATAGTTCATGTGGTAAAAGAGGGAAGTCTTTTACACTATTATGTTGTACTTAAAAGTACTAA
GAATAAGATTGTTATTGCTGATCCGGACCCTACTAGTGGAATTAAAAAGATATCTAAAAAAGCATTTGAAAAGGAGTGGA
CAGGTGTCACTTTATTGATGATTCCAAAATCTAATTTTAAAGTAATAAAAGAAAAGAAGACTAATCTTATATCTCTTTTA
CCTTATTTGTTTAAGCAGAAAACTTTAATTAAAAATATTATTTTAGCCACGATACTCGTAACTTTAATTAGTATAGGGAC
TTCGTATTTTGTTCAAGGCCTAATTGATACTTATATTCCAAATGAAGCCTACACAATTTTATCTATTTTAGCTATTGGAT
TATTAATAGCATATGTATTTAATTCTATTTTTCAATATGGCCAACAAGTTTTGTTAAATATATTAGGGCAACGTTTGTCT
ATAGATCTTAACTTGCAATACATTAGGCATGTGTTTGAACTTCCAATGGAATTTTTTACTACGCGTAAAACAGGAGAGAT
TACATCTCGATTTTCTGATGCTAGTAGGATTATTGATGCTTTGGCCAGAATGGTGATCTCTTTATTTCTTGCTTTATCGA
TTGTAATTTTGATGGGAATAGTTTTAGCACTTCAAAATATGACTTTATTTTTAATTACACTTTTTTCTATTCCAATCTAT
GCAATCATTATTCTCGGATTTACGAAAAAATTTGAAAAGCTAAATAATGATCAAATGGAAAGTAATGCAGTAGTAAGTTC
TTCAATTATTGAAGATATTCAAGGAATAGAAACTATTAAAGCATTAAACAGTGAACAGATTCGATATCGTAAAATTGATG
AGCAATTTGTTGATTATTTAAGAAAGGCTTTCAAGTATAGTAAGAATGAGACCTTACAAACAGTACTGAAGACTTTTGTT
CGCTTGGCATTAAATATAGTTGTCTTGTGGGTAGGGGCAATTATTGTAATGCATAACCAAATGTCCATTGGTCAATTAAT
GGCCTTTAATGCATTATTAGCTTATTTTGTTGATCCATTGCAGAATATAATTAATTTACAGCCTACTCTTCAAGCTGCCA
ATGTGGCTCAAAATCGTTTAAATGAAGTTTATTTAGTTAAAAGCGAATTTAATAAAACAGCCTCTATTAATAAAATTCAA
CAAATTGAAGGAGATATTCATTTGACGCATGTTTATTATCGCTATGGATATGGGAGTGATGTCTTACAAAATATAAGTCT
TAAAATAAGCCCTGGTGAAAAATTAACTATTGTGGGAATGAGTGGTTCTGGTAAATCAACATTAGTTAAATTATTGGTGG
CTTTTTATAGTCCTACAAAAGGTAAGCTAACCTTTAATAATAAAGCAGTAAGTAATATTGATAAGCATATTCTTCGCTCT
TATGTAAATTATGTACCGCAAATTCCATGTGTATTTTCAGGAACGATTAAAGAAAATTTGTTATTAGGTAGTCGACCTCA
TATTTCTGATGAAGAAATAAAAAAAGCATGTCAAATTGCAGAAATTAAAGATGATATTGAAAAATTACCGTTGCAATATG
ACACTCCACTTGATGAAAATGCAAAGGTACTATCAGGAGGTCAAAAGCAACGCTTAACGATTGCTAGAGCTCTTTTAACA
CCTGCTAAGGTATTGATTTTAGATGAAGCGACTAGTGGATTAGATACTATTACTGAGAAAAAGGTAGTAAATAACTTACT
TCAGCTTAAAGATAAAACTATTATTTTTATAGCCCATCGCTTATCTATCGCTAAAAAAACAGATAACATTATAGTTTTAA
GTAAAGGCCAAATTGTTGAACATGGGAGTCATAAAGAACTGATGGCAGCACAGGGCTATTATTATAATTTAGTAAAAAGT
TAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (173-440)

• Peptidase C39 family (Peptidase_C39) (10-144)

• ABC transporter (ABC_tran) (502-652)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus gordonii str. Challis substr. CH1	54.993	98.75	0.543
comA	Streptococcus mitis NCTC 12261	54.571	98.75	0.539
comA	Streptococcus pneumoniae R6	54.43	98.75	0.537
comA	Streptococcus pneumoniae TIGR4	54.43	98.75	0.537
comA	Streptococcus pneumoniae Rx1	54.43	98.75	0.537
comA	Streptococcus pneumoniae D39	54.43	98.75	0.537
comA	Streptococcus mitis SK321	54.29	98.75	0.536
comA/nlmT	Streptococcus mutans UA159	53.182	98.194	0.522