Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   J9537_RS02110 Genome accession   NZ_CP072888
Coordinates   417537..418835 (-) Length   432 a.a.
NCBI ID   WP_218256546.1    Uniprot ID   -
Organism   Enterococcus raffinosus strain F162_2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 412537..423835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J9537_RS02080 (J9537_02080) - 413588..414103 (-) 516 WP_218256543.1 DUF3237 domain-containing protein -
  J9537_RS02085 (J9537_02085) - 414265..415500 (+) 1236 WP_218256544.1 helix-turn-helix domain-containing protein -
  J9537_RS02090 (J9537_02090) - 415567..415884 (+) 318 WP_010747028.1 thioredoxin family protein -
  J9537_RS02095 (J9537_02095) - 415894..416349 (+) 456 WP_010747027.1 universal stress protein -
  J9537_RS02100 (J9537_02100) ytpR 416462..417073 (+) 612 WP_218256545.1 YtpR family tRNA-binding protein -
  J9537_RS02105 (J9537_02105) - 417243..417428 (+) 186 WP_010747025.1 hypothetical protein -
  J9537_RS02110 (J9537_02110) htrA 417537..418835 (-) 1299 WP_218256546.1 trypsin-like peptidase domain-containing protein Regulator
  J9537_RS02115 (J9537_02115) rlmH 419295..419774 (+) 480 WP_218256547.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  J9537_RS02120 (J9537_02120) - 419853..420242 (+) 390 WP_218256548.1 DUF4279 domain-containing protein -
  J9537_RS02125 (J9537_02125) - 420353..420739 (+) 387 WP_218256549.1 hypothetical protein -
  J9537_RS02130 (J9537_02130) - 421046..421438 (+) 393 WP_218256550.1 Imm70 family immunity protein -
  J9537_RS02135 (J9537_02135) - 421539..421727 (+) 189 WP_218256551.1 DUF960 family protein -
  J9537_RS02140 (J9537_02140) - 421796..422248 (-) 453 WP_218256552.1 DUF2188 domain-containing protein -
  J9537_RS02145 (J9537_02145) - 422415..423743 (+) 1329 WP_218256553.1 FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 45267.57 Da        Isoelectric Point: 4.7980

>NTDB_id=556627 J9537_RS02110 WP_218256546.1 417537..418835(-) (htrA) [Enterococcus raffinosus strain F162_2]
MIRKDITPTPKKPLGFFRRFGISLLGGVLGAVLTIGIFYVASGSLLSPSNQNASGSPSAGNTKVSNMKVDVNSDITEAAS
KVQDAVVSVINLQKQQSQSGLGGFSDIFGNRNDDQQSQDDSGQLEEASEGSGVIYKLEGNTAYIVTNNHVVEKQDGLEVL
LKDGSKVKATLVGTDSYTDLAVLKVESDKVANIKPATFGDSSSLKVGEPAIALGSPLGSQYANSVTSGIISSLNRQVVNQ
NDEGQTVNINAIQTDAAINPGNSGGPLVNMAGQVVGINSSKIVQTESNVSVEGIGFAIPSNDVVNVINQLEKDGKVIRPA
LGITMASLSDLSTEQVSEIVKVPSSVTQGVVVGSVQSSTPADQAGLKKYDVITKIDDTDVSSGVELQSELYKHKVGDTVK
ITYYRQDKKNTVSVKLSIDSNSLKSNSQQGNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=556627 J9537_RS02110 WP_218256546.1 417537..418835(-) (htrA) [Enterococcus raffinosus strain F162_2]
ATGATAAGAAAAGACATTACCCCAACACCCAAAAAGCCACTCGGTTTTTTTAGACGGTTTGGGATTAGTTTATTAGGCGG
TGTACTTGGCGCTGTCTTAACAATAGGAATCTTTTACGTAGCGAGTGGTTCGTTACTATCTCCAAGTAATCAAAACGCCA
GCGGCTCGCCTAGTGCAGGTAACACGAAGGTCAGTAACATGAAGGTTGATGTAAACTCTGATATTACCGAAGCAGCCAGC
AAGGTGCAAGACGCGGTTGTTTCTGTTATTAACTTGCAGAAGCAGCAATCACAAAGCGGCTTAGGCGGCTTCTCTGATAT
ATTCGGTAATAGAAATGATGATCAGCAGTCGCAAGATGATAGTGGGCAACTGGAAGAAGCCTCTGAAGGTTCAGGTGTCA
TCTACAAGCTGGAGGGCAATACCGCCTACATCGTTACAAATAATCACGTTGTGGAAAAACAAGATGGTTTGGAAGTATTG
TTAAAGGATGGTTCAAAAGTGAAGGCAACCTTAGTCGGTACGGATTCCTATACTGACTTAGCTGTTTTAAAGGTTGAATC
AGACAAAGTCGCAAACATCAAACCCGCAACTTTTGGTGATTCAAGTAGCTTAAAGGTTGGTGAGCCAGCAATCGCGTTAG
GTTCTCCTCTAGGCTCACAGTACGCTAACTCAGTGACTTCAGGGATTATTTCTTCCTTGAATCGTCAAGTAGTCAACCAA
AATGATGAAGGTCAAACCGTCAACATCAATGCGATCCAAACAGATGCAGCTATTAACCCTGGTAACTCTGGCGGTCCGTT
AGTCAACATGGCTGGTCAAGTAGTCGGTATCAACTCTAGTAAGATCGTTCAGACAGAGTCAAATGTCAGTGTGGAAGGAA
TCGGCTTTGCTATTCCAAGTAATGATGTAGTGAACGTTATTAACCAGCTTGAAAAAGATGGCAAAGTAATTCGCCCAGCT
CTAGGCATTACGATGGCTAGCCTATCTGATCTTTCGACTGAACAAGTAAGTGAGATTGTTAAGGTACCAAGTTCTGTTAC
TCAAGGAGTCGTGGTGGGAAGCGTACAATCATCTACACCAGCGGATCAGGCAGGCTTGAAGAAGTATGATGTCATCACAA
AAATTGATGATACCGATGTTTCATCGGGTGTCGAACTGCAATCTGAATTGTACAAACATAAAGTCGGCGATACAGTGAAA
ATTACCTACTATCGTCAAGATAAGAAAAATACAGTTTCAGTAAAATTGAGCATTGATTCGAATTCATTGAAATCAAACTC
ACAACAAGGGAACCAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(319-416)

Trypsin-like peptidase domain (Trypsin_2)

(130-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

50.24

96.296

0.484
  htrA Streptococcus mutans UA159

50

95.833

0.479
  htrA Streptococcus pneumoniae Rx1

49.639

96.065

0.477
  htrA Streptococcus pneumoniae R6

49.639

96.065

0.477
  htrA Streptococcus pneumoniae TIGR4

49.639

96.065

0.477
  htrA Streptococcus pneumoniae D39

49.639

96.065

0.477
  htrA Streptococcus mitis NCTC 12261

49.639

96.065

0.477