Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   LZ175_RS02165 Genome accession   NZ_CP090448
Coordinates   441850..442974 (+) Length   374 a.a.
NCBI ID   WP_230069284.1    Uniprot ID   -
Organism   Escherichia coli strain PT62     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 436850..447974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LZ175_RS02140 (LZ175_02140) mscL 436976..437386 (-) 411 WP_000022439.1 large-conductance mechanosensitive channel protein MscL -
  LZ175_RS02145 (LZ175_02145) trkA 437516..438892 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  LZ175_RS02150 (LZ175_02150) rsmB 438914..440203 (-) 1290 WP_040063958.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  LZ175_RS02155 (LZ175_02155) fmt 440249..441196 (-) 948 WP_001402578.1 methionyl-tRNA formyltransferase -
  LZ175_RS02160 (LZ175_02160) def 441211..441720 (-) 510 WP_000114984.1 peptide deformylase -
  LZ175_RS02165 (LZ175_02165) dprA 441850..442974 (+) 1125 WP_230069284.1 DNA-protecting protein DprA Machinery gene
  LZ175_RS02170 (LZ175_02170) smg 442946..443419 (+) 474 WP_000460670.1 DUF494 family protein Smg -
  LZ175_RS02175 (LZ175_02175) yrdD 443448..443990 (+) 543 WP_001129723.1 type I DNA topoisomerase -
  LZ175_RS02180 (LZ175_02180) tsaC 443995..444567 (+) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  LZ175_RS02185 (LZ175_02185) aroE 444572..445390 (+) 819 WP_001411435.1 shikimate dehydrogenase -
  LZ175_RS02190 (LZ175_02190) yrdB 445387..445644 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  LZ175_RS02195 (LZ175_02195) yrdA 445620..446174 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41014.97 Da        Isoelectric Point: 6.3122

>NTDB_id=554035 LZ175_RS02165 WP_230069284.1 441850..442974(+) (dprA) [Escherichia coli strain PT62]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLVTTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPSPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=554035 LZ175_RS02165 WP_230069284.1 441850..442974(+) (dprA) [Escherichia coli strain PT62]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGTGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGTGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGGTTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGTATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTTTAAGTAAAGGCGTACTGGTGGTGGAAGCTGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCTAGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.238

98.663

0.476
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

44.324

98.93

0.438
  dprA Vibrio cholerae strain A1552

44.324

98.93

0.438
  dprA Glaesserella parasuis strain SC1401

44.838

90.642

0.406
  dprA Haemophilus influenzae Rd KW20

44.51

90.107

0.401
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388