NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	LXN07_RS02260	Genome accession	NZ_CP090196
Coordinates	482466..483590 (+)	Length	374 a.a.
NCBI ID	WP_001521436.1	Uniprot ID	-
Organism	Escherichia coli strain YL3
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 477466..488590

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXN07_RS02235 (LXN07_02235)	mscL	477592..478002 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
LXN07_RS02240 (LXN07_02240)	trkA	478132..479508 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
LXN07_RS02245 (LXN07_02245)	rsmB	479530..480819 (-)	1290	WP_001308993.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LXN07_RS02250 (LXN07_02250)	fmt	480865..481812 (-)	948	WP_000004456.1	methionyl-tRNA formyltransferase	-
LXN07_RS02255 (LXN07_02255)	def	481827..482336 (-)	510	WP_000114984.1	peptide deformylase	-
LXN07_RS02260 (LXN07_02260)	dprA	482466..483590 (+)	1125	WP_001521436.1	DNA-protecting protein DprA	Machinery gene
LXN07_RS02265 (LXN07_02265)	smg	483562..484035 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
LXN07_RS02270 (LXN07_02270)	yrdD	484064..484606 (+)	543	WP_001129723.1	type I DNA topoisomerase	-
LXN07_RS02275 (LXN07_02275)	tsaC	484611..485183 (+)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
LXN07_RS02280 (LXN07_02280)	aroE	485188..486006 (+)	819	WP_001521434.1	shikimate dehydrogenase	-
LXN07_RS02285 (LXN07_02285)	yrdB	486003..486260 (+)	258	WP_001521433.1	DUF1488 domain-containing protein	-
LXN07_RS02290 (LXN07_02290)	yrdA	486236..486790 (-)	555	WP_001286217.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40994.94 Da Isoelectric Point: 6.2655

                                >NTDB_id=553315 LXN07_RS02260 WP_001521436.1 482466..483590(+) (dprA) [Escherichia coli strain YL3]

MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=553315 LXN07_RS02260 WP_001521436.1 482466..483590(+) (dprA) [Escherichia coli strain YL3]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT

TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	48.71	82.888	0.404
dprA	Vibrio cholerae strain A1552	48.71	82.888	0.404
dprA	Glaesserella parasuis strain SC1401	44.807	90.107	0.404
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	43.939	88.235	0.388

Detailed information NTG0553315