Detailed information NTG0553244

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: J7U24_RS09060
• Genome accession: NZ_CP072440
• Coordinates: 1733232..1733669 (-)
• Length: 145 a.a.
• NCBI ID: WP_011681686.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24730
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1728232..1738669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U24_RS09020 (J7U24_08995)	-	1728296..1728958 (-)	663	WP_014727719.1	CPBP family intramembrane glutamic endopeptidase	-
J7U24_RS09025 (J7U24_09000)	-	1729055..1729498 (-)	444	WP_041829335.1	hypothetical protein	-
J7U24_RS09030	-	1729572..1729910 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
J7U24_RS09035	-	1729954..1730229 (-)	276	WP_372434690.1	CAAX protease	-
J7U24_RS09040 (J7U24_09010)	-	1730241..1730438 (-)	198	WP_014727723.1	helix-turn-helix transcriptional regulator	-
J7U24_RS09045 (J7U24_09015)	-	1730687..1731880 (-)	1194	WP_014608740.1	acetate kinase	-
J7U24_RS09050 (J7U24_09020)	comYH	1731936..1732892 (-)	957	WP_372434691.1	class I SAM-dependent methyltransferase	Machinery gene
J7U24_RS09055 (J7U24_09025)	comGG	1732937..1733254 (-)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	-
J7U24_RS09060 (J7U24_09030)	comYF	1733232..1733669 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
J7U24_RS09065 (J7U24_09035)	comGE	1733653..1733946 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
J7U24_RS09070 (J7U24_09040)	comYD	1733918..1734346 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
J7U24_RS09075 (J7U24_09045)	comYC	1734306..1734632 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
J7U24_RS09080 (J7U24_09050)	comYB	1734629..1735729 (-)	1101	WP_142350125.1	competence type IV pilus assembly protein ComGB	Machinery gene
J7U24_RS09085 (J7U24_09055)	comGA/cglA/cilD	1735611..1736552 (-)	942	WP_071417491.1	competence type IV pilus ATPase ComGA	Machinery gene
J7U24_RS09090 (J7U24_09060)	-	1736633..1736995 (-)	363	WP_014622006.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.85 Da
• Isoelectric Point: 8.4500

>NTDB_id=553244 J7U24_RS09060 WP_011681686.1 1733232..1733669(-) (comYF) [Streptococcus thermophilus strain S24730]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=553244 J7U24_RS09060 WP_011681686.1 1733232..1733669(-) (comYF) [Streptococcus thermophilus strain S24730]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae Rx1	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae R6	49.286	96.552	0.476
comGF/cglF	Streptococcus pneumoniae TIGR4	49.286	96.552	0.476
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.809	97.241	0.455
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434