Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   J7U24_RS00960 Genome accession   NZ_CP072440
Coordinates   169777..170526 (+) Length   249 a.a.
NCBI ID   WP_372434701.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24730     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 164777..175526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U24_RS00935 (J7U24_00940) - 165352..165522 (+) 171 WP_023909348.1 hypothetical protein -
  J7U24_RS00940 (J7U24_00945) - 165803..166543 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  J7U24_RS00945 (J7U24_00950) - 166543..168093 (-) 1551 WP_014607891.1 ABC transporter substrate-binding protein/permease -
  J7U24_RS00950 (J7U24_00955) - 168296..169150 (+) 855 WP_014607892.1 undecaprenyl-diphosphate phosphatase -
  J7U24_RS00955 (J7U24_00960) - 169296..169511 (-) 216 WP_011226805.1 DUF3021 family protein -
  J7U24_RS00960 (J7U24_00965) mecA 169777..170526 (+) 750 WP_372434701.1 adaptor protein MecA Regulator
  J7U24_RS00965 (J7U24_00970) - 170530..171687 (+) 1158 WP_372434702.1 glycosyltransferase family 4 protein -
  J7U24_RS00970 (J7U24_00975) sufC 171848..172618 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  J7U24_RS00975 (J7U24_00980) sufD 172655..173917 (+) 1263 WP_372429528.1 Fe-S cluster assembly protein SufD -
  J7U24_RS00980 (J7U24_00985) - 173971..175203 (+) 1233 WP_220016546.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29051.62 Da        Isoelectric Point: 4.0808

>NTDB_id=553197 J7U24_RS00960 WP_372434701.1 169777..170526(+) (mecA) [Streptococcus thermophilus strain S24730]
MEMKQINETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTGPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=553197 J7U24_RS00960 WP_372434701.1 169777..170526(+) (mecA) [Streptococcus thermophilus strain S24730]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGCCCTTGATTTTAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGGGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAACTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMG 18311

99.197

100

0.992
  mecA Streptococcus thermophilus LMD-9

98.394

100

0.984
  mecA Streptococcus mutans UA159

58.197

97.992

0.57
  mecA Streptococcus pneumoniae Rx1

46.185

100

0.462
  mecA Streptococcus pneumoniae D39

46.185

100

0.462
  mecA Streptococcus pneumoniae R6

46.185

100

0.462
  mecA Streptococcus pneumoniae TIGR4

46.185

100

0.462