Detailed information NTG0553188

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: J7T81_RS09245
• Genome accession: NZ_CP072439
• Coordinates: 1782370..1783470 (-)
• Length: 366 a.a.
• NCBI ID: WP_116920398.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24732
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1777370..1788470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T81_RS09200	-	1777695..1777970 (-)	276	WP_011681681.1	hypothetical protein	-
J7T81_RS09205 (J7T81_09140)	-	1777982..1778179 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
J7T81_RS09210 (J7T81_09145)	-	1778428..1779621 (-)	1194	WP_014608740.1	acetate kinase	-
J7T81_RS09215 (J7T81_09150)	comYH	1779677..1780633 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
J7T81_RS09220 (J7T81_09155)	comGG	1780678..1780995 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
J7T81_RS09225 (J7T81_09160)	comYF	1780973..1781410 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
J7T81_RS09230 (J7T81_09165)	comGE	1781394..1781687 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
J7T81_RS09235 (J7T81_09170)	comYD	1781659..1782087 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
J7T81_RS09240 (J7T81_09175)	comYC	1782047..1782373 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
J7T81_RS09245 (J7T81_09180)	comYB	1782370..1783470 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
J7T81_RS09250 (J7T81_09185)	comGA/cglA/cilD	1783352..1784293 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
J7T81_RS09255 (J7T81_09190)	-	1784374..1784736 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41797.91 Da
• Isoelectric Point: 10.1084

>NTDB_id=553188 J7T81_RS09245 WP_116920398.1 1782370..1783470(-) (comYB) [Streptococcus thermophilus strain S24732]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=553188 J7T81_RS09245 WP_116920398.1 1782370..1783470(-) (comYB) [Streptococcus thermophilus strain S24732]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413