Detailed information NTG0553185

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: J7T81_RS09225
• Genome accession: NZ_CP072439
• Coordinates: 1780973..1781410 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24732
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1775973..1786410

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T81_RS09185 (J7T81_09125)	-	1776037..1776699 (-)	663	WP_011681679.1	CPBP family intramembrane glutamic endopeptidase	-
J7T81_RS09190 (J7T81_09130)	-	1776796..1777239 (-)	444	WP_011681680.1	hypothetical protein	-
J7T81_RS09195	-	1777313..1777738 (-)	426	WP_014608739.1	CPBP family intramembrane glutamic endopeptidase	-
J7T81_RS09200	-	1777695..1777970 (-)	276	WP_011681681.1	hypothetical protein	-
J7T81_RS09205 (J7T81_09140)	-	1777982..1778179 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
J7T81_RS09210 (J7T81_09145)	-	1778428..1779621 (-)	1194	WP_014608740.1	acetate kinase	-
J7T81_RS09215 (J7T81_09150)	comYH	1779677..1780633 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
J7T81_RS09220 (J7T81_09155)	comGG	1780678..1780995 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
J7T81_RS09225 (J7T81_09160)	comYF	1780973..1781410 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
J7T81_RS09230 (J7T81_09165)	comGE	1781394..1781687 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
J7T81_RS09235 (J7T81_09170)	comYD	1781659..1782087 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
J7T81_RS09240 (J7T81_09175)	comYC	1782047..1782373 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
J7T81_RS09245 (J7T81_09180)	comYB	1782370..1783470 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
J7T81_RS09250 (J7T81_09185)	comGA/cglA/cilD	1783352..1784293 (-)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
J7T81_RS09255 (J7T81_09190)	-	1784374..1784736 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=553185 J7T81_RS09225 WP_014608742.1 1780973..1781410(-) (comYF) [Streptococcus thermophilus strain S24732]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=553185 J7T81_RS09225 WP_014608742.1 1780973..1781410(-) (comYF) [Streptococcus thermophilus strain S24732]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441