Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   J7T60_RS01575 Genome accession   NZ_CP072436
Coordinates   285081..285914 (+) Length   277 a.a.
NCBI ID   WP_269149495.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24735     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 269070..285914 285081..285914 within 0


Gene organization within MGE regions


Location: 269070..285914
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T60_RS01475 (J7T60_01465) - 269070..271025 (+) 1956 WP_372433482.1 DNA methyltransferase -
  J7T60_RS01480 (J7T60_01470) - 271027..273744 (+) 2718 WP_260214889.1 DEAD/DEAH box helicase family protein -
  J7T60_RS01485 (J7T60_01475) - 274033..274242 (-) 210 Protein_239 transposase -
  J7T60_RS01490 (J7T60_01480) - 274484..274690 (-) 207 WP_162484320.1 hypothetical protein -
  J7T60_RS01495 (J7T60_01485) - 274809..275339 (-) 531 WP_011681029.1 hypothetical protein -
  J7T60_RS01500 (J7T60_01490) - 275403..275990 (-) 588 WP_372433483.1 hypothetical protein -
  J7T60_RS01505 (J7T60_01495) - 276373..276873 (-) 501 WP_220015960.1 hypothetical protein -
  J7T60_RS01510 (J7T60_01500) - 277092..277367 (-) 276 WP_179974136.1 hypothetical protein -
  J7T60_RS01515 (J7T60_01505) - 277384..277569 (-) 186 WP_023909306.1 hypothetical protein -
  J7T60_RS01520 (J7T60_01510) - 277867..279375 (-) 1509 WP_372433484.1 phage/plasmid primase, P4 family -
  J7T60_RS01525 (J7T60_01515) - 279365..280225 (-) 861 WP_372433485.1 primase alpha helix C-terminal domain-containing protein -
  J7T60_RS01530 (J7T60_01520) - 280241..280514 (-) 274 Protein_248 MerR family transcriptional regulator -
  J7T60_RS01535 (J7T60_01525) - 280608..280856 (-) 249 WP_372433486.1 hypothetical protein -
  J7T60_RS01540 (J7T60_01530) - 280843..281079 (-) 237 WP_372433487.1 hypothetical protein -
  J7T60_RS01545 (J7T60_01535) - 281093..281299 (-) 207 WP_022096594.1 hypothetical protein -
  J7T60_RS01550 (J7T60_01540) - 281303..281608 (-) 306 WP_347230089.1 hypothetical protein -
  J7T60_RS01555 (J7T60_01545) - 281826..282023 (-) 198 WP_372433488.1 helix-turn-helix domain-containing protein -
  J7T60_RS01560 (J7T60_01550) - 282186..282704 (+) 519 WP_372433489.1 helix-turn-helix domain-containing protein -
  J7T60_RS01565 (J7T60_01555) - 282823..283989 (+) 1167 WP_372433490.1 tyrosine-type recombinase/integrase -
  J7T60_RS01570 - 284064..285059 (+) 996 Protein_256 ABC transporter transmembrane domain-containing protein -
  J7T60_RS01575 comA 285081..285914 (+) 834 WP_269149495.1 ATP-binding cassette domain-containing protein Regulator

Sequence

Protein


Download         Length: 277 a.a.        Molecular weight: 30866.48 Da        Isoelectric Point: 8.8523

>NTDB_id=552969 J7T60_RS01575 WP_269149495.1 285081..285914(+) (comA) [Streptococcus thermophilus strain S24735]
MITYSMLLNYFTTPLINIINLQSKIQQAKVANNCLQEVYVVNKEEKGQLKDLSFKQLDLKGVSHRFRYQQETLHNIDLTI
NKGEKIALMGQSSSGKTTLAKILSGYYTKSSGHVSLDKASISQAELRQLVTYVPQQTYVFTGTILENLLLGLEGEVDGHF
ILKVCEQADILADIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSNQPILIFDEATSGLDRKTESRVMANLSELTRTM
IFIAHRSSVYQHVSRVVTMANGKLEAASTNFNPFQFI

Nucleotide


Download         Length: 834 bp        

>NTDB_id=552969 J7T60_RS01575 WP_269149495.1 285081..285914(+) (comA) [Streptococcus thermophilus strain S24735]
TTGATTACCTATAGTATGTTGCTTAATTATTTTACGACTCCTTTAATTAATATTATCAATCTTCAATCTAAGATTCAGCA
AGCCAAGGTAGCCAATAATTGTCTTCAAGAAGTTTATGTTGTGAATAAGGAAGAAAAAGGTCAACTCAAAGATTTATCCT
TTAAACAATTAGACTTAAAAGGTGTTAGTCATCGTTTCAGATACCAACAAGAGACACTTCATAATATTGATTTGACGATT
AATAAGGGAGAGAAAATCGCCCTCATGGGTCAGAGTAGTTCTGGGAAAACGACTTTAGCGAAGATTTTGTCAGGTTATTA
CACAAAATCTAGTGGTCATGTAAGCTTAGACAAAGCTTCTATTAGCCAAGCGGAGTTGCGCCAGTTGGTGACCTATGTTC
CACAACAGACCTATGTGTTTACGGGAACAATATTAGAAAATCTATTGTTAGGCCTTGAAGGAGAAGTTGATGGTCATTTT
ATTCTGAAAGTCTGTGAACAAGCCGATATTTTGGCTGATATTCAAAAGATGCCCCTAGGTTTTCAGACCCAAGTATCTGA
AGATGGAGGTCTGTCTGGCGGTCAAAAACAAAGATTAGCTATAGCAAGGGCTCTCTTGTCCAATCAACCAATCTTGATTT
TTGATGAAGCTACAAGTGGTCTGGACAGGAAAACTGAAAGTAGAGTAATGGCCAATCTTTCTGAACTGACACGAACAATG
ATTTTCATTGCTCACCGTAGCAGTGTCTACCAACATGTCAGTCGTGTAGTGACTATGGCAAATGGGAAGCTTGAAGCAGC
TAGTACCAACTTCAATCCATTCCAGTTCATTTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(73-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

50

98.195

0.491
  comA Streptococcus mitis NCTC 12261

50

98.195

0.491
  comA Streptococcus pneumoniae D39

49.632

98.195

0.487
  comA Streptococcus pneumoniae R6

49.632

98.195

0.487
  comA Streptococcus pneumoniae Rx1

49.632

98.195

0.487
  comA Streptococcus gordonii str. Challis substr. CH1

49.632

98.195

0.487
  comA Streptococcus pneumoniae TIGR4

49.265

98.195

0.484
  comA/nlmT Streptococcus mutans UA159

45.956

98.195

0.451