NTDB

Overview

Name	vicR	Type	Regulator
Locus tag	J7U00_RS04560	Genome accession	NZ_CP072431
Coordinates	866974..867681 (+)	Length	235 a.a.
NCBI ID	WP_011681206.1	Uniprot ID	-
Organism	Streptococcus thermophilus strain S24745
Function	repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 861974..872681

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U00_RS04530 (J7U00_04525)	-	862254..862442 (+)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
J7U00_RS04535 (J7U00_04530)	endA	862504..863385 (+)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
J7U00_RS04540 (J7U00_04535)	-	863457..864107 (-)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7U00_RS04545 (J7U00_04540)	-	864119..864817 (-)	699	WP_011681209.1	amino acid ABC transporter permease	-
J7U00_RS04550 (J7U00_04545)	-	864835..865668 (-)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
J7U00_RS04555 (J7U00_04550)	-	865680..866447 (-)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
J7U00_RS04560 (J7U00_04555)	vicR	866974..867681 (+)	708	WP_011681206.1	response regulator YycF	Regulator
J7U00_RS04565 (J7U00_04560)	vicK	867674..869014 (+)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
J7U00_RS04570 (J7U00_04565)	vicX	869020..869832 (+)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
J7U00_RS04575 (J7U00_04570)	-	869892..870253 (+)	362	Protein_896	YbaN family protein	-
J7U00_RS04580 (J7U00_04575)	-	870305..871519 (-)	1215	WP_002953123.1	aminoacyltransferase	-
J7U00_RS04585 (J7U00_04580)	yidA	871521..872330 (-)	810	WP_011226081.1	sugar-phosphatase	-

Sequence

Protein

Download Length: 235 a.a. Molecular weight: 27058.98 Da Isoelectric Point: 5.0130

                                >NTDB_id=552750 J7U00_RS04560 WP_011681206.1 866974..867681(+) (vicR) [Streptococcus thermophilus strain S24745]

MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA

KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL

THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

Download Length: 708 bp

                                >NTDB_id=552750 J7U00_RS04560 WP_011681206.1 866974..867681(+) (vicR) [Streptococcus thermophilus strain S24745]

ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA

AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA

TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT

AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA

ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA

AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG

ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC

CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA

CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387

Detailed information NTG0552750