Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   J7T92_RS01060 Genome accession   NZ_CP072429
Coordinates   182779..183528 (+) Length   249 a.a.
NCBI ID   WP_372589770.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24747     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 177779..188528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T92_RS01035 (J7T92_01050) - 178355..178525 (+) 171 WP_023909348.1 hypothetical protein -
  J7T92_RS01040 (J7T92_01055) - 178806..179546 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  J7T92_RS01045 (J7T92_01060) - 179546..181096 (-) 1551 WP_014607891.1 ABC transporter substrate-binding protein/permease -
  J7T92_RS01050 (J7T92_01065) - 181299..182153 (+) 855 WP_014607892.1 undecaprenyl-diphosphate phosphatase -
  J7T92_RS01055 (J7T92_01070) - 182298..182513 (-) 216 WP_011226805.1 DUF3021 family protein -
  J7T92_RS01060 (J7T92_01075) mecA 182779..183528 (+) 750 WP_372589770.1 adaptor protein MecA Regulator
  J7T92_RS01065 (J7T92_01080) - 183532..184689 (+) 1158 WP_138496642.1 glycosyltransferase family 4 protein -
  J7T92_RS01070 (J7T92_01085) sufC 184850..185620 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  J7T92_RS01075 (J7T92_01090) sufD 185657..186919 (+) 1263 WP_372429528.1 Fe-S cluster assembly protein SufD -
  J7T92_RS01080 (J7T92_01095) - 186973..188205 (+) 1233 WP_220016546.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29085.63 Da        Isoelectric Point: 4.0808

>NTDB_id=552615 J7T92_RS01060 WP_372589770.1 182779..183528(+) (mecA) [Streptococcus thermophilus strain S24747]
MEMKQINETTLKIMITMEDLEEHGMGLKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEALDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=552615 J7T92_RS01060 WP_372589770.1 182779..183528(+) (mecA) [Streptococcus thermophilus strain S24747]
ATGGAAATGAAACAAATAAACGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGGGCT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGCCCTTGATTTTAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMG 18311

99.598

100

0.996
  mecA Streptococcus thermophilus LMD-9

98.795

100

0.988
  mecA Streptococcus mutans UA159

56.967

97.992

0.558
  mecA Streptococcus pneumoniae Rx1

45.783

100

0.458
  mecA Streptococcus pneumoniae D39

45.783

100

0.458
  mecA Streptococcus pneumoniae R6

45.783

100

0.458
  mecA Streptococcus pneumoniae TIGR4

45.783

100

0.458