Detailed information NTG0552524

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: J7T78_RS05645
• Genome accession: NZ_CP072427
• Coordinates: 1091647..1092354 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24750
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1086647..1097354

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T78_RS05620 (J7T78_05605)	yidA	1086998..1087807 (+)	810	WP_011226081.1	sugar-phosphatase	-
J7T78_RS05625 (J7T78_05610)	-	1087809..1089023 (+)	1215	WP_002953123.1	aminoacyltransferase	-
J7T78_RS05630 (J7T78_05615)	-	1089075..1089436 (-)	362	Protein_1067	YbaN family protein	-
J7T78_RS05635 (J7T78_05620)	vicX	1089496..1090308 (-)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
J7T78_RS05640 (J7T78_05625)	vicK	1090314..1091654 (-)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
J7T78_RS05645 (J7T78_05630)	vicR	1091647..1092354 (-)	708	WP_011681206.1	response regulator YycF	Regulator
J7T78_RS05650 (J7T78_05635)	-	1092881..1093648 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
J7T78_RS05655 (J7T78_05640)	-	1093660..1094493 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
J7T78_RS05660 (J7T78_05645)	-	1094511..1095209 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
J7T78_RS05665 (J7T78_05650)	-	1095221..1095871 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7T78_RS05670 (J7T78_05655)	endA	1095943..1096824 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
J7T78_RS05675 (J7T78_05660)	-	1096886..1097074 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=552524 J7T78_RS05645 WP_011681206.1 1091647..1092354(-) (vicR) [Streptococcus thermophilus strain S24750]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=552524 J7T78_RS05645 WP_011681206.1 1091647..1092354(-) (vicR) [Streptococcus thermophilus strain S24750]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387