Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   J4854_RS03670 Genome accession   NZ_CP072329
Coordinates   702566..704812 (+) Length   748 a.a.
NCBI ID   WP_200772275.1    Uniprot ID   A0A9X0WMF7
Organism   Streptococcus lactarius strain CCUG 66490     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 697566..709812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS03650 (J4854_03650) - 697769..698515 (-) 747 WP_200772271.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  J4854_RS03655 (J4854_03655) - 698595..700934 (-) 2340 WP_200772272.1 HAD-IC family P-type ATPase -
  J4854_RS03660 (J4854_03660) - 701104..701850 (+) 747 WP_200772273.1 lysophospholipid acyltransferase family protein -
  J4854_RS03665 (J4854_03665) comEA/celA/cilE 701917..702585 (+) 669 WP_200772274.1 helix-hairpin-helix domain-containing protein Machinery gene
  J4854_RS03670 (J4854_03670) comEC/celB 702566..704812 (+) 2247 WP_200772275.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  J4854_RS03675 (J4854_03675) - 704888..705490 (+) 603 WP_200772276.1 DUF805 domain-containing protein -
  J4854_RS03680 (J4854_03680) holA 705514..706548 (+) 1035 WP_200772277.1 DNA polymerase III subunit delta -
  J4854_RS03685 (J4854_03685) sodA 706637..707242 (+) 606 WP_200772278.1 superoxide dismutase SodA -
  J4854_RS03690 (J4854_03690) - 707436..708905 (+) 1470 WP_200772279.1 helicase HerA-like domain-containing protein -

Sequence

Protein


Download         Length: 748 a.a.        Molecular weight: 85555.05 Da        Isoelectric Point: 9.3866

>NTDB_id=552045 J4854_RS03670 WP_200772275.1 702566..704812(+) (comEC/celB) [Streptococcus lactarius strain CCUG 66490]
MLSRWIKQFPFSPVHLAFLLLCLYFSVYQPSFQTEIILVVALFLLVNRYKNERQSLIKLAVLAVCFAGFFFIQRFLNEHK
SGASQPPAQLRLLPDAIKINGDLLSFRATDQGNTYQVFYQLKSEKEKKQWQSQTQSMDISYKGRMEEPVGQRNFRGFDYR
AYLKTQGIHYQITIESFRSAVPSKTWNLFDWCSQLRRKAIVWSKEHFPHPMNQYMTGLLFGYLDTDFEEMDQLYSSLGII
HLFALSGMQVGFFINGIRKILLRLGILQETVEFMMYPLSFLYAGLTGFSVSVVRSLLQKLLSQKGIVGMENMAVTIMFLM
VFMPFFLLTAGGVLSCAYAFILTLIDTSSYVGFKKVLLESTCISLGILPFLTYYFAVFQPWSIPLTFIFSFLFDLVLLPG
LTVLFLFSFLKPLTIFNTVFILIEACIRWIADGTSLPLVFGQPTGLALLGLIFLLGVLYDLRKKKGLRLLCIGAIFLVFA
WTKHPLENEITMVDIGQGDSIFLRDWKGRTILIDVGGRVSFKSGEKWQERHQSANAEKTLLPYLKSRGVGKIDALVVTHT
DQDHMGDMLEVARQIPIQTIYISQGSLTQPKFQEQLKQLHSSIKVVNRGDHLPIFESYLEVLSPDGVGDGKNNDSIVLYG
QFFQKRFLFTGDLEEAGEKQLLANYPKLEVDVLKVGHHGSKGSSSDAFLDQLHPQLALISVGKKNRYQHPHKELLERLEK
RSISYLRTDERGAIRLIGWDHWRLETVR

Nucleotide


Download         Length: 2247 bp        

>NTDB_id=552045 J4854_RS03670 WP_200772275.1 702566..704812(+) (comEC/celB) [Streptococcus lactarius strain CCUG 66490]
ATGCTTTCACGGTGGATTAAGCAGTTTCCCTTTTCGCCAGTTCACTTAGCCTTTTTATTGCTGTGTTTGTATTTCAGTGT
CTACCAACCTTCATTTCAGACGGAGATCATTCTTGTCGTCGCTCTATTCTTGTTGGTCAATCGATATAAAAATGAGCGTC
AAAGCTTGATTAAGCTTGCAGTTCTGGCAGTTTGTTTTGCTGGCTTCTTTTTTATTCAGCGTTTTCTAAACGAGCACAAA
AGTGGAGCATCTCAGCCACCGGCTCAGTTACGTTTACTGCCAGATGCGATTAAGATCAATGGTGATTTGCTGAGTTTTCG
AGCAACAGATCAAGGAAACACATACCAAGTCTTTTATCAGTTGAAATCAGAAAAGGAAAAAAAGCAATGGCAATCACAAA
CGCAGTCCATGGATATTTCGTATAAAGGAAGGATGGAAGAGCCGGTAGGTCAGCGAAATTTTCGAGGATTTGATTACCGT
GCTTATTTGAAGACGCAAGGAATCCACTATCAAATCACTATTGAGTCTTTTCGATCGGCTGTGCCTTCTAAAACCTGGAA
TCTGTTTGATTGGTGCTCCCAATTGAGGCGCAAAGCCATAGTTTGGAGCAAGGAACACTTTCCGCATCCAATGAATCAGT
ATATGACAGGACTTCTCTTTGGCTATCTAGATACTGATTTTGAAGAGATGGACCAGCTCTATTCCAGCTTAGGCATTATC
CATTTGTTTGCCTTATCGGGAATGCAAGTTGGATTTTTCATCAATGGTATTCGAAAAATCCTCTTACGCTTGGGAATACT
GCAAGAAACGGTAGAATTTATGATGTATCCTCTTTCCTTTCTTTACGCTGGTTTGACGGGTTTTTCAGTCTCTGTTGTTC
GTAGCCTTCTGCAAAAACTATTGTCCCAAAAAGGGATTGTTGGAATGGAGAATATGGCAGTTACAATCATGTTTTTGATG
GTTTTTATGCCTTTTTTCCTTCTTACTGCCGGCGGTGTCTTAAGTTGTGCGTATGCCTTTATTTTGACCCTGATAGATAC
GAGTTCCTATGTTGGTTTTAAAAAAGTACTACTGGAAAGTACTTGCATTAGCTTAGGCATATTGCCATTTTTAACCTATT
ATTTTGCTGTCTTTCAACCCTGGTCCATTCCGCTGACCTTTATCTTTTCCTTTTTATTTGACCTTGTCTTGCTTCCAGGT
TTGACTGTTTTGTTTCTATTCTCTTTTTTAAAACCTTTGACCATCTTTAATACTGTCTTTATCTTAATCGAGGCGTGTAT
CCGCTGGATCGCAGATGGGACGTCACTTCCCCTAGTATTTGGTCAACCGACAGGGTTGGCTCTGCTTGGCTTGATCTTTC
TTTTGGGGGTCCTCTATGATCTTAGAAAGAAAAAAGGGTTGCGCTTACTTTGTATAGGAGCTATCTTTCTTGTCTTTGCT
TGGACCAAGCACCCTTTAGAAAATGAGATTACGATGGTCGATATTGGCCAAGGAGATAGTATCTTTTTACGAGATTGGAA
AGGCCGGACGATCTTAATTGATGTGGGTGGACGTGTCAGTTTTAAGAGCGGAGAAAAGTGGCAGGAGCGTCATCAGTCGG
CCAATGCTGAGAAAACCCTCCTTCCTTACCTTAAGAGTCGAGGGGTTGGAAAAATCGATGCCTTGGTTGTGACACATACG
GATCAGGACCACATGGGAGATATGCTTGAGGTGGCCAGACAAATTCCAATTCAAACGATTTATATCAGTCAGGGAAGCCT
CACCCAACCCAAATTTCAAGAGCAGTTGAAACAGCTTCATAGTTCGATCAAAGTTGTCAATAGAGGCGATCACTTACCTA
TATTTGAGAGTTACCTAGAGGTCTTATCCCCTGATGGAGTGGGTGATGGGAAAAATAATGATTCAATCGTCTTATATGGA
CAGTTTTTTCAAAAACGATTTCTATTTACTGGGGACCTTGAAGAAGCAGGAGAAAAACAACTTTTAGCCAATTATCCAAA
ACTAGAAGTAGACGTCTTAAAAGTGGGGCACCATGGATCAAAAGGATCTTCGAGCGACGCCTTTTTAGATCAATTACATC
CTCAACTGGCCTTGATTTCAGTTGGAAAGAAGAATCGTTACCAGCATCCCCATAAAGAATTGTTGGAACGATTGGAGAAG
CGTTCGATTTCTTACCTTCGTACCGATGAAAGAGGGGCTATTCGATTGATTGGCTGGGATCATTGGAGGCTGGAGACTGT
CCGCTAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(496-701)

Competence protein (Competence)

(218-463)

Domain of unknown function (DUF4131) (DUF4131)

(37-175)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.293

100

0.549
  comEC/celB Streptococcus mitis NCTC 12261

53.316

100

0.537
  comEC/celB Streptococcus pneumoniae TIGR4

52.793

100

0.531
  comEC/celB Streptococcus pneumoniae Rx1

52.527

100

0.528
  comEC/celB Streptococcus pneumoniae D39

52.527

100

0.528
  comEC/celB Streptococcus pneumoniae R6

52.527

100

0.528
  comEC Lactococcus lactis subsp. cremoris KW2

47.043

99.465

0.468