Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   J4854_RS02655 Genome accession   NZ_CP072329
Coordinates   509970..511838 (+) Length   622 a.a.
NCBI ID   WP_200772973.1    Uniprot ID   -
Organism   Streptococcus lactarius strain CCUG 66490     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 504970..516838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS02640 (J4854_02640) fmt 506973..507908 (+) 936 WP_200772975.1 methionyl-tRNA formyltransferase -
  J4854_RS02645 (J4854_02645) rsmB 507898..509211 (+) 1314 WP_200772974.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  J4854_RS02650 (J4854_02650) - 509233..509973 (+) 741 WP_187538269.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  J4854_RS02655 (J4854_02655) stkP 509970..511838 (+) 1869 WP_200772973.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  J4854_RS02660 (J4854_02660) liaF 512003..512698 (+) 696 WP_200772972.1 cell wall-active antibiotics response protein LiaF -
  J4854_RS02665 (J4854_02665) - 512695..513711 (+) 1017 WP_200772971.1 sensor histidine kinase -
  J4854_RS02670 (J4854_02670) - 513708..514340 (+) 633 WP_200772970.1 response regulator transcription factor -
  J4854_RS02675 (J4854_02675) - 514385..515785 (+) 1401 WP_200772969.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  J4854_RS02680 (J4854_02680) - 515787..516152 (+) 366 WP_200772968.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 622 a.a.        Molecular weight: 68327.35 Da        Isoelectric Point: 5.6543

>NTDB_id=552035 J4854_RS02655 WP_200772973.1 509970..511838(+) (stkP) [Streptococcus lactarius strain CCUG 66490]
MIQIGKIFAGRYKIIQQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMAELDHPNIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTCGIIHRDLKPQNVLLTPDGTAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIREENKNVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSCLSYERRNEPKLVFEDQTKADTKTLPKVNPTPKTAPVPISEVRSEISSI
DANRPSTDPQTVAPNKKPRRRLRTRYKVLFVAIALVLAAFAFLLYMSPANKTVPDVSGKTVAEARALIEGQDLQVGDEKE
EYSDSVAEGYVIRTSPNAGAQKKEQSRIDLIVSKGPNSFEMPNYVGETRAKAEDDLKNTYKVSSKMISIEEVETFDYEPG
TVIEQTPAPGEQYSLNSKTKIVLKVAKESTSVEMPNYIGSTYDFARSNLIEIYGIKEANIELKKTDHLPDGVFVSAGQIV
SQSPEASSSVDINRTRIVLTVYEPKVTSSSSTKASSSSSETSSSSSSERSDTESSSSTAAGN

Nucleotide


Download         Length: 1869 bp        

>NTDB_id=552035 J4854_RS02655 WP_200772973.1 509970..511838(+) (stkP) [Streptococcus lactarius strain CCUG 66490]
ATGATTCAAATCGGCAAAATTTTTGCCGGACGATATAAAATCATCCAACAAATTGGTCGCGGGGGGATGGCAGATGTCTA
TCTAGCGCGTGATTTAATTTTGGATGGTGAAGAAGTCGCTGTTAAAGTTCTGCGTACAAATTACCAGACAGATCCCATTG
CAGTTGCACGTTTTCAGCGTGAAGCAAAAGCGATGGCAGAACTGGACCATCCAAATATCGTTCGGATTACAGATATCGGT
GAAGAAGAAGGGCAACAATACCTTGCAATGGAATACGTTGCCGGTTTAGATTTGAAGCGTTACATTAAAGAAAATGCGCC
ACTATCAAATGAAGAAGCCGTTCGTTTGATGGGACAAATTCTTCTAGCAATGCGCCTAGCCCATACATGTGGTATCATTC
ATAGAGATTTAAAACCGCAAAATGTCCTTTTAACTCCTGATGGGACTGCTAAAGTTTCGGATTTTGGGATTGCGGTAGCC
TTTGCGGAAACTAGTTTGACTCAGACCAACTCAATGCTAGGATCCGTTCATTATTTGTCACCTGAGCAGGCGCGTGGATC
AAAAGCTACGGTTCAAAGTGACATCTACGCTATGGGGATTATTTTCTATGAGATGTTGACAGGGCACATTCCATACGATG
GAGATAGTGCTGTTACAATTGCCCTGCAGCATTTCCAAAAACCTCTACCTTCGATTCGTGAGGAAAATAAGAACGTCCCC
CAAGCTTTAGAAAATGTCGTCATCAAAGCGACAGCTAAGAAACTGACAGATCGGTACAAATCAGTAGCTGAGATGTACGT
GGATCTTTCAAGTTGTTTGTCGTATGAAAGAAGAAACGAACCCAAACTAGTTTTTGAAGATCAAACGAAGGCAGACACCA
AAACACTTCCTAAAGTGAACCCAACTCCAAAAACTGCTCCAGTTCCCATCTCTGAAGTACGTAGTGAAATTAGTTCGATA
GATGCGAATCGTCCATCTACAGATCCGCAGACGGTGGCACCAAATAAAAAGCCAAGAAGACGATTACGCACACGTTACAA
GGTCTTGTTTGTAGCTATCGCTTTGGTCCTCGCTGCTTTTGCGTTCTTATTGTATATGAGTCCCGCTAATAAAACAGTAC
CAGATGTTTCTGGCAAGACTGTTGCAGAAGCGCGGGCACTGATTGAAGGACAAGATCTCCAAGTAGGAGATGAAAAGGAG
GAATACAGCGATTCGGTTGCAGAAGGCTATGTGATCCGTACCAGTCCGAATGCAGGGGCTCAAAAGAAGGAACAGAGTCG
AATTGATTTGATTGTCTCCAAGGGGCCAAACAGTTTTGAAATGCCAAACTACGTAGGTGAAACACGAGCAAAAGCTGAAG
ATGATCTCAAAAATACCTATAAAGTATCTAGTAAGATGATCAGTATTGAAGAGGTTGAAACCTTTGATTATGAACCTGGA
ACGGTTATTGAGCAAACACCGGCACCGGGTGAACAATACTCTTTGAACTCAAAAACTAAGATTGTATTGAAAGTAGCCAA
AGAATCAACGTCTGTTGAAATGCCAAACTATATTGGATCAACCTATGATTTTGCTCGAAGCAATTTGATTGAAATCTATG
GAATCAAAGAAGCGAATATTGAATTGAAGAAAACCGATCATCTACCAGATGGAGTATTCGTATCCGCTGGTCAGATTGTC
AGCCAATCACCAGAGGCTTCAAGTAGTGTCGATATCAATCGTACACGAATTGTCTTGACGGTTTATGAACCGAAAGTAAC
CTCTTCATCTAGTACAAAAGCTTCCTCTTCTAGCTCAGAAACTTCTAGCTCCTCTTCTTCTGAACGATCAGACACTGAAA
GTTCAAGTAGTACAGCTGCTGGAAATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-244)

PASTA domain (PASTA)

(512-582)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(440-507)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

62.375

96.141

0.6
  stkP Streptococcus pneumoniae D39

62.207

96.141

0.598
  stkP Streptococcus pneumoniae R6

62.207

96.141

0.598
  stkP Streptococcus pneumoniae Rx1

62.04

96.141

0.596
  stkP/pknB Streptococcus salivarius strain HSISS4

54.669

94.695

0.518
  pknB Streptococcus mutans UA159

58.932

87.299

0.514