Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   J4854_RS02190 Genome accession   NZ_CP072329
Coordinates   410430..411167 (+) Length   245 a.a.
NCBI ID   WP_200773103.1    Uniprot ID   A0A9X1BBD1
Organism   Streptococcus lactarius strain CCUG 66490     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 405430..416167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS02175 (J4854_02175) - 405710..407284 (-) 1575 WP_187538105.1 ABC transporter substrate-binding protein/permease -
  J4854_RS02180 (J4854_02180) - 407404..409308 (+) 1905 WP_200773104.1 DUF2207 domain-containing protein -
  J4854_RS02185 (J4854_02185) - 409457..410293 (+) 837 WP_187538109.1 undecaprenyl-diphosphate phosphatase -
  J4854_RS02190 (J4854_02190) mecA 410430..411167 (+) 738 WP_200773103.1 adaptor protein MecA Regulator
  J4854_RS02195 (J4854_02195) - 411164..412327 (+) 1164 WP_200773102.1 glycosyltransferase family 4 protein -
  J4854_RS02200 (J4854_02200) sufC 412455..413225 (+) 771 WP_187538115.1 Fe-S cluster assembly ATPase SufC -
  J4854_RS02205 (J4854_02205) sufD 413289..414551 (+) 1263 WP_200773101.1 Fe-S cluster assembly protein SufD -
  J4854_RS02210 (J4854_02210) - 414561..415787 (+) 1227 WP_200773100.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28299.97 Da        Isoelectric Point: 4.1646

>NTDB_id=552027 J4854_RS02190 WP_200773103.1 410430..411167(+) (mecA) [Streptococcus lactarius strain CCUG 66490]
MKMKQISDSTIKITIQLEDLEERGMEIADFLVPQEKTEEFFYAILDELEMPESFLDSGMLSFRVTPKPDKLDVFVTKSKI
DQQLDFDDLSELPDMEELSHMTPDEFIKTLEKTISDKTKGDAEAIHHLEQEELRANQENKEVSELPASQYIYFILHFSTL
QQVVDFAKTVTYSVDTSELYKMESDYYLTVLVDTEHQPSQYPTWLLAIIREYADDSEVTRAVLQEHGHLLMVSGAIENLK
KVASL

Nucleotide


Download         Length: 738 bp        

>NTDB_id=552027 J4854_RS02190 WP_200773103.1 410430..411167(+) (mecA) [Streptococcus lactarius strain CCUG 66490]
ATGAAAATGAAGCAAATAAGTGATTCAACAATTAAAATCACGATTCAACTAGAAGACCTAGAAGAAAGAGGAATGGAAAT
CGCGGATTTCCTTGTTCCACAAGAAAAGACAGAAGAATTTTTCTATGCGATTTTAGATGAGCTCGAAATGCCTGAAAGTT
TCCTAGATAGTGGAATGCTGAGCTTTCGTGTCACTCCTAAGCCAGATAAATTAGATGTTTTTGTCACTAAATCAAAGATT
GACCAACAATTGGATTTTGACGATTTATCAGAGCTGCCAGATATGGAAGAGTTGTCCCATATGACGCCTGATGAATTCAT
CAAGACCTTGGAAAAAACTATCTCTGACAAGACAAAAGGAGATGCAGAGGCTATTCATCATCTAGAGCAAGAAGAACTGC
GGGCTAATCAAGAGAACAAAGAGGTATCGGAGCTACCGGCCAGCCAATATATCTATTTTATCTTGCATTTTTCAACACTT
CAGCAAGTGGTGGATTTTGCGAAGACGGTCACGTATTCAGTTGATACTTCTGAATTGTACAAGATGGAATCTGATTATTA
TTTAACTGTCTTAGTAGATACAGAACACCAACCAAGCCAATACCCAACTTGGTTATTAGCAATCATTCGTGAGTACGCGG
ATGATTCCGAAGTGACGCGCGCAGTCTTACAAGAGCATGGTCACTTGCTGATGGTGTCAGGTGCGATTGAGAATTTGAAG
AAAGTTGCTAGCCTATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

68.163

100

0.682
  mecA Streptococcus pneumoniae D39

68.163

100

0.682
  mecA Streptococcus pneumoniae R6

68.163

100

0.682
  mecA Streptococcus pneumoniae TIGR4

68.163

100

0.682
  mecA Streptococcus mutans UA159

49.393

100

0.498
  mecA Streptococcus thermophilus LMD-9

47.154

100

0.473
  mecA Streptococcus thermophilus LMG 18311

46.748

100

0.469