Detailed information NTG0550561

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: J5M87_RS09760
• Genome accession: NZ_CP072115
• Coordinates: 2090419..2091636 (+)
• Length: 405 a.a.
• NCBI ID: WP_375138169.1
• Uniprot ID: -
• Organism: Streptococcus zhangguiae strain zg-86
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2085419..2096636

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J5M87_RS09730 (J5M87_09730)	-	2085873..2088443 (+)	2571	WP_154607653.1	YfhO family protein	-
J5M87_RS09750 (J5M87_09750)	-	2089091..2089762 (-)	672	WP_154607654.1	YoaK family protein	-
J5M87_RS09755 (J5M87_09755)	rlmH	2089795..2090274 (-)	480	WP_154607655.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
J5M87_RS09760 (J5M87_09760)	htrA	2090419..2091636 (+)	1218	WP_375138169.1	S1C family serine protease	Regulator
J5M87_RS09765 (J5M87_09765)	spo0J	2091694..2092458 (+)	765	WP_154607657.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 405 a.a.
• Molecular weight: 42775.07 Da
• Isoelectric Point: 4.8959

>NTDB_id=550561 J5M87_RS09760 WP_375138169.1 2090419..2091636(+) (htrA) [Streptococcus zhangguiae strain zg-86]
MEETICMKKTVNYLLILVIGFVGGLAGTLVAPLLHPTNQPNQVVETKKDNEQTTVSNVQYDNQNSTTTAVEKVQNAVVSV
INYQKARDNGYRSILGSNETNDELAVAGEGSGVIYKKTDQFAYLVTNTHVIAGAEKIDIQLASGEKVEGELIGSDTYADI
AVIKIAADKVKNVAEFANSDKIKVGETAIAIGSPLGSIYANTVTQGIVSSLSRTVTSKAEDGQTISTNAIQTDTAINPGN
SGGPLINIQGQVIGITSSKITSSSNSAAGVAVEGMGFAIPANDAVNIINQLEKNGKVIRPALGIQMVNLSNLSTEQRKKA
GLDSDTVKTGIVVVSTQQGLPADGQLKQYDVITKIDGEKVETTSDLQSALYKHTVGDTISITYSRNGKEKTIDIKLTHST
EDLSN

Nucleotide

• Length: 1218 bp

>NTDB_id=550561 J5M87_RS09760 WP_375138169.1 2090419..2091636(+) (htrA) [Streptococcus zhangguiae strain zg-86]
TTGGAGGAAACTATCTGCATGAAAAAAACTGTAAACTATCTACTCATACTCGTAATTGGATTTGTTGGAGGCTTAGCAGG
AACTCTTGTCGCTCCTTTACTTCATCCAACAAATCAACCGAATCAAGTTGTAGAAACAAAAAAAGATAATGAACAGACTA
CTGTAAGTAATGTCCAATATGATAATCAAAATTCAACAACAACAGCCGTTGAAAAAGTTCAAAATGCAGTCGTATCTGTC
ATTAATTATCAAAAAGCGCGTGACAATGGCTATCGCTCCATACTGGGAAGCAATGAAACAAATGATGAACTAGCTGTTGC
GGGCGAGGGGTCTGGTGTTATCTATAAGAAAACAGATCAATTTGCCTATCTTGTCACTAACACTCATGTCATCGCAGGGG
CTGAAAAAATCGATATTCAACTTGCTTCTGGTGAAAAAGTGGAAGGTGAGTTAATTGGATCAGATACCTATGCCGATATA
GCCGTTATCAAAATTGCTGCTGATAAGGTGAAAAATGTTGCTGAATTTGCGAACTCTGATAAAATAAAAGTTGGAGAAAC
AGCCATTGCTATTGGTAGTCCGCTTGGTAGTATTTATGCCAATACTGTCACTCAAGGGATCGTTTCCAGTCTTAGCCGTA
CAGTTACTTCAAAAGCAGAAGACGGTCAAACGATTTCAACTAATGCTATTCAGACAGATACCGCTATTAACCCGGGTAAT
TCAGGTGGCCCACTAATCAATATTCAAGGACAAGTTATTGGTATTACCTCTAGCAAAATCACTTCTAGTTCCAATTCTGC
AGCAGGAGTCGCTGTAGAAGGAATGGGATTTGCAATTCCAGCAAATGATGCTGTCAATATCATCAATCAACTAGAGAAAA
ATGGGAAAGTCATTCGTCCAGCACTCGGCATTCAAATGGTGAATTTAAGTAATTTATCAACTGAGCAACGGAAAAAAGCT
GGTCTTGATAGCGATACAGTGAAAACAGGTATTGTCGTTGTCTCTACTCAACAAGGTTTACCAGCAGATGGACAACTCAA
ACAATACGATGTCATTACAAAAATTGACGGAGAAAAGGTTGAAACAACCAGTGACCTCCAAAGTGCACTTTACAAGCATA
CTGTCGGTGATACTATCTCTATTACTTATTCTCGTAATGGAAAAGAAAAAACTATTGACATCAAATTGACACATTCAACA
GAAGATTTATCAAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (110-255)

• PDZ domain (PDZ_2) (300-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	61.194	99.259	0.607
htrA	Streptococcus mutans UA159	61.013	97.531	0.595
htrA	Streptococcus mitis NCTC 12261	58.942	98.025	0.578
htrA	Streptococcus pneumoniae Rx1	58.69	98.025	0.575
htrA	Streptococcus pneumoniae D39	58.69	98.025	0.575
htrA	Streptococcus pneumoniae R6	58.69	98.025	0.575
htrA	Streptococcus pneumoniae TIGR4	58.69	98.025	0.575