Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   J5M87_RS08230 Genome accession   NZ_CP072115
Coordinates   1755811..1757796 (-) Length   661 a.a.
NCBI ID   WP_154608913.1    Uniprot ID   A0A6I4RKR7
Organism   Streptococcus zhangguiae strain zg-86     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1750811..1762796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5M87_RS08205 (J5M87_08205) - 1751136..1751501 (-) 366 WP_154608918.1 S1 RNA-binding domain-containing protein -
  J5M87_RS08210 (J5M87_08210) - 1751503..1752903 (-) 1401 WP_154608917.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  J5M87_RS08215 (J5M87_08215) - 1753202..1753846 (-) 645 WP_154608916.1 response regulator transcription factor -
  J5M87_RS08220 (J5M87_08220) - 1753815..1754834 (-) 1020 WP_160463302.1 sensor histidine kinase -
  J5M87_RS08225 (J5M87_08225) liaF 1754834..1755529 (-) 696 WP_154608914.1 cell wall-active antibiotics response protein LiaF -
  J5M87_RS08230 (J5M87_08230) stkP 1755811..1757796 (-) 1986 WP_154608913.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  J5M87_RS08235 (J5M87_08235) - 1757793..1758533 (-) 741 WP_154608912.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  J5M87_RS08240 (J5M87_08240) rsmB 1758552..1759862 (-) 1311 WP_154608911.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  J5M87_RS08245 (J5M87_08245) fmt 1759852..1760787 (-) 936 WP_154608910.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 70983.84 Da        Isoelectric Point: 6.7887

>NTDB_id=550553 J5M87_RS08230 WP_154608913.1 1755811..1757796(-) (stkP) [Streptococcus zhangguiae strain zg-86]
MIQIGKIFADRYRIVRQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDQIAVQRFQREARAMAELDHPNIVRISDIG
EEDGQQYLAMEYVDGLDLKRYIKENAPLSNDEAVRIMGQILLAMRMAHTKGIVHRDLKPQNVLLTRNGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIVLFEMLTGRIPYDGDSAVTIALQHFQKALPSVRESNPQVP
QALENVVLKATAKKLAERYKTVAEMYADIASSLSSNRLYEKKVLLEDGKVDTKTLPKLASIATDQRIPSGKSTPSETATR
GGERVASLPVKTKKRVRTRYKVLFATIFLIIAAIVALLYNTPAAIRVPDVSGQTLEVARETIETAGLKVGKITEEPSSEV
EEGKVIRTNPAADTSKKEGSSIDIVVATTDAVTVPDVVGKSFDDAKIELEAAGFVVKETQEYSASVEENKVISTDPKANS
SKAKGSAVTVTVSKGAERHQIPNIRGKSLEAATQELKAIGLIIGTTTEEYSDTVQKGLIAKVNPEIGVEVPKGTAVNVVI
SKGPVPVMPDFGALRVSYTEAKRQLQALGVADDEIVKEIESNYIASSGDLVVGQFPAPGAAINGRVTLYVSVAGTISSSA
TNTADTGTSSGTTTNNNGSGN

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=550553 J5M87_RS08230 WP_154608913.1 1755811..1757796(-) (stkP) [Streptococcus zhangguiae strain zg-86]
ATGATTCAGATTGGAAAAATCTTTGCGGATCGCTACCGAATCGTCCGACAAATAGGACGTGGGGGAATGGCGGATGTTTA
TCTAGCAAAAGATTTGATTTTAGATGGAGAAGAAGTAGCGGTTAAGGTACTTCGGACCAACTATCAAACAGACCAGATTG
CAGTCCAACGTTTTCAGCGAGAAGCAAGAGCGATGGCAGAACTAGACCACCCCAATATTGTACGTATTTCAGATATTGGT
GAAGAAGATGGTCAGCAATATCTAGCCATGGAATACGTTGATGGACTAGATTTAAAGCGGTATATCAAAGAGAATGCCCC
TTTGTCAAATGATGAAGCGGTGCGGATTATGGGTCAAATTTTGTTAGCGATGAGAATGGCCCATACAAAGGGAATTGTTC
ACCGCGACTTGAAACCCCAAAACGTTTTGTTGACAAGAAATGGAACTGCAAAAGTGACAGACTTTGGGATTGCTGTGGCC
TTTGCAGAAACGAGTCTAACCCAGACGAATTCTATGTTAGGATCGGTACATTATTTGTCACCAGAACAGGCCCGTGGTTC
AAAGGCGACAGTACAAAGTGACATCTATGCAATGGGAATTGTACTCTTTGAAATGTTGACAGGGCGGATTCCCTATGACG
GAGATAGTGCGGTGACGATTGCTCTCCAGCATTTTCAAAAAGCCTTGCCTTCTGTCAGAGAATCCAATCCTCAAGTACCA
CAAGCCCTTGAAAATGTTGTCTTAAAAGCAACGGCAAAAAAATTGGCAGAACGCTACAAGACAGTAGCTGAGATGTATGC
AGATATTGCTTCTTCTCTTTCCAGCAATCGCTTGTACGAAAAGAAAGTCTTGCTAGAGGATGGGAAAGTAGATACAAAAA
CTCTGCCAAAACTAGCGAGTATTGCTACTGACCAACGAATTCCTTCTGGGAAGTCTACCCCATCAGAAACAGCGACAAGA
GGAGGTGAGCGTGTAGCAAGCCTTCCTGTTAAAACTAAAAAAAGGGTACGTACTCGATATAAGGTTCTTTTTGCAACAAT
TTTTCTGATTATTGCAGCGATTGTAGCTCTTCTTTACAATACACCTGCAGCGATAAGAGTACCAGATGTTAGTGGGCAGA
CCTTAGAGGTTGCAAGAGAAACGATTGAAACAGCTGGATTGAAAGTTGGAAAGATTACAGAAGAACCCTCTTCAGAAGTA
GAAGAAGGAAAGGTTATCCGAACAAATCCAGCAGCAGACACATCGAAGAAAGAAGGAAGCAGCATTGATATTGTTGTTGC
AACGACAGATGCAGTGACCGTTCCGGATGTGGTTGGAAAGAGTTTTGATGATGCCAAAATTGAACTAGAGGCGGCTGGTT
TTGTTGTAAAAGAAACACAAGAATATAGTGCAAGTGTTGAAGAAAATAAAGTTATCTCAACAGATCCTAAGGCAAATTCG
TCAAAGGCGAAAGGCAGTGCAGTGACAGTAACCGTTTCAAAGGGAGCTGAGCGACATCAGATTCCTAATATCCGTGGAAA
GAGTTTGGAAGCTGCTACTCAAGAATTAAAAGCAATCGGCTTAATAATTGGAACAACGACTGAAGAATATAGCGATACGG
TTCAAAAAGGTTTGATTGCAAAAGTAAATCCAGAAATTGGTGTAGAAGTTCCAAAAGGAACGGCAGTAAATGTAGTCATT
TCCAAAGGTCCGGTGCCAGTTATGCCTGATTTTGGTGCTTTGAGAGTGAGTTATACAGAAGCGAAGCGACAATTGCAAGC
CTTGGGAGTAGCAGATGATGAGATTGTAAAAGAAATTGAATCAAATTATATTGCTTCCTCAGGTGATTTGGTCGTTGGTC
AATTTCCAGCACCGGGTGCTGCTATCAATGGGCGCGTGACTCTATATGTGTCAGTAGCAGGAACAATCTCTTCTAGCGCA
ACGAATACAGCAGACACTGGTACTTCTTCAGGAACCACGACAAACAATAATGGTTCAGGAAACTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-234)

PASTA domain (PASTA)

(577-631)

PASTA domain (PASTA)

(432-494)

PASTA domain (PASTA)

(366-427)

PASTA domain (PASTA)

(500-562)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I4RKR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

53.776

100

0.539
  stkP Streptococcus pneumoniae D39

53.474

100

0.536
  stkP Streptococcus pneumoniae R6

53.474

100

0.536
  stkP Streptococcus pneumoniae Rx1

53.323

100

0.534
  stkP/pknB Streptococcus salivarius strain HSISS4

55.21

82.753

0.457
  pknB Streptococcus mutans UA159

55.888

80.938

0.452