Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   J5M87_RS01800 Genome accession   NZ_CP072115
Coordinates   338700..339428 (+) Length   242 a.a.
NCBI ID   WP_154609073.1    Uniprot ID   A0A6I4RCB1
Organism   Streptococcus zhangguiae strain zg-86     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 333700..344428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5M87_RS01780 (J5M87_01780) - 334335..334544 (+) 210 WP_075098784.1 hypothetical protein -
  J5M87_RS01785 (J5M87_01785) - 334730..335479 (-) 750 WP_154609070.1 amino acid ABC transporter ATP-binding protein -
  J5M87_RS01790 (J5M87_01790) - 335472..337037 (-) 1566 WP_154609071.1 ABC transporter substrate-binding protein/permease -
  J5M87_RS01795 (J5M87_01795) - 337165..338004 (+) 840 WP_154609072.1 undecaprenyl-diphosphate phosphatase -
  J5M87_RS01800 (J5M87_01800) mecA 338700..339428 (+) 729 WP_154609073.1 adaptor protein MecA Regulator
  J5M87_RS01805 (J5M87_01805) - 339425..340603 (+) 1179 WP_154609074.1 glycosyltransferase family 4 protein -
  J5M87_RS01810 (J5M87_01810) sufC 340684..341454 (+) 771 WP_154609075.1 Fe-S cluster assembly ATPase SufC -
  J5M87_RS01815 (J5M87_01815) sufD 341484..342746 (+) 1263 WP_154609076.1 Fe-S cluster assembly protein SufD -
  J5M87_RS01820 (J5M87_01820) - 342752..343981 (+) 1230 WP_154609077.1 cysteine desulfurase -
  J5M87_RS01825 (J5M87_01825) sufU 343968..344402 (+) 435 WP_154609078.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28148.73 Da        Isoelectric Point: 4.0090

>NTDB_id=550522 J5M87_RS01800 WP_154609073.1 338700..339428(+) (mecA) [Streptococcus zhangguiae strain zg-86]
MKMKQISDSTLKITIKMEDLEERGMELADFLVPQEKTEEFFYTVLDELELPVTFRESGMLSFRVTPKPDKVDIFVTKSDI
DQQLNFDDFADMADLDELSHMTPDEFLKTLEKTIREKSAGDNQAVQHLEQVEEAELDEEEEEDIRNYIYYILDFASLQEA
VQFVSLVDFTVEESELYKMNDRYYMTVLINIENRSTRYPDYILSRMLEHADDTSISRAVLQEHGILLLPVAAIEELGKVS
LA

Nucleotide


Download         Length: 729 bp        

>NTDB_id=550522 J5M87_RS01800 WP_154609073.1 338700..339428(+) (mecA) [Streptococcus zhangguiae strain zg-86]
ATGAAGATGAAACAAATCAGTGATTCAACCTTGAAAATCACGATAAAAATGGAAGATTTGGAAGAGCGTGGAATGGAATT
GGCAGATTTTCTAGTACCACAGGAAAAGACAGAAGAATTTTTCTATACCGTGCTAGATGAATTAGAATTACCAGTAACCT
TCCGTGAAAGTGGGATGCTGAGTTTTCGTGTGACGCCAAAACCAGATAAGGTTGATATTTTTGTGACAAAATCAGACATT
GATCAGCAACTGAACTTTGATGATTTTGCGGATATGGCAGATTTAGATGAACTGTCACACATGACACCAGATGAATTTTT
GAAGACACTTGAGAAAACCATTCGCGAAAAGAGTGCAGGTGATAACCAAGCTGTTCAACATTTGGAGCAGGTAGAAGAAG
CTGAGCTTGATGAAGAAGAGGAAGAGGACATCCGTAATTATATTTACTATATCCTTGATTTTGCGAGTCTTCAGGAGGCT
GTTCAGTTTGTGTCCCTTGTTGATTTTACAGTTGAGGAATCAGAATTGTACAAGATGAATGATCGCTACTATATGACAGT
TTTGATCAATATTGAAAATCGCTCCACACGCTATCCAGACTACATTTTGTCACGAATGTTAGAGCATGCAGATGATACTT
CTATTTCACGTGCAGTCCTTCAAGAGCATGGTATTCTACTACTCCCAGTTGCTGCAATTGAGGAGCTTGGGAAGGTGAGT
CTAGCATGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I4RCB1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

59.592

100

0.603
  mecA Streptococcus pneumoniae D39

59.592

100

0.603
  mecA Streptococcus pneumoniae R6

59.592

100

0.603
  mecA Streptococcus pneumoniae TIGR4

59.592

100

0.603
  mecA Streptococcus mutans UA159

51.429

100

0.521
  mecA Streptococcus thermophilus LMD-9

49.167

99.174

0.488
  mecA Streptococcus thermophilus LMG 18311

48.75

99.174

0.483