Detailed information NTG0055003

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: EFS1_RS12665
• Genome accession: NC_019770
• Coordinates: 2515377..2516675 (+)
• Length: 432 a.a.
• NCBI ID: WP_010709051.1
• Uniprot ID: -
• Organism: Enterococcus faecalis str. Symbioflor
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2510377..2521675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EFS1_RS12660 (EFS1_2469)	rlmH	2514497..2514976 (-)	480	WP_002355021.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EFS1_RS12665 (EFS1_2470)	htrA	2515377..2516675 (+)	1299	WP_010709051.1	S1C family serine protease	Regulator
EFS1_RS12670 (EFS1_2471)	ytpR	2516722..2517342 (-)	621	WP_002361057.1	YtpR family tRNA-binding protein	-
EFS1_RS12675 (EFS1_2472)	-	2517553..2518008 (-)	456	WP_002385249.1	universal stress protein	-
EFS1_RS12680 (EFS1_2473)	-	2518156..2518470 (-)	315	WP_002355015.1	thioredoxin family protein	-
EFS1_RS12685 (EFS1_2474)	pepA	2518482..2519558 (-)	1077	WP_002389404.1	glutamyl aminopeptidase	-
EFS1_RS12690 (EFS1_2475)	-	2519865..2520206 (+)	342	WP_002355012.1	PepSY domain-containing protein	-

Sequence

Protein

• Length: 432 a.a.
• Molecular weight: 44830.97 Da
• Isoelectric Point: 5.1142

>NTDB_id=55003 EFS1_RS12665 WP_010709051.1 2515377..2516675(+) (htrA) [Enterococcus faecalis str. Symbioflor]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIQGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide

• Length: 1299 bp

>NTDB_id=55003 EFS1_RS12665 WP_010709051.1 2515377..2516675(+) (htrA) [Enterococcus faecalis str. Symbioflor]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACATCCACTAATCACGGCGACACAAAAGTCAGCAATGTAAGTTACAATGTGTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGAAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCAATTG
GTTCCCCTCTAGGCTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTCAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACTATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (9-416)

• PDZ domain (PDZ_2) (319-416)

• Trypsin-like peptidase domain (Trypsin_2) (132-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	53.415	94.907	0.507
htrA	Streptococcus mutans UA159	58.63	84.491	0.495
htrA	Streptococcus mitis NCTC 12261	55.405	85.648	0.475
htrA	Streptococcus pneumoniae TIGR4	56.091	81.713	0.458
htrA	Streptococcus pneumoniae Rx1	56.091	81.713	0.458
htrA	Streptococcus pneumoniae D39	56.091	81.713	0.458
htrA	Streptococcus pneumoniae R6	56.091	81.713	0.458