Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   J3S98_RS04930 Genome accession   NZ_CP071729
Coordinates   966088..968235 (-) Length   715 a.a.
NCBI ID   WP_041931940.1    Uniprot ID   A0AAD1K2D7
Organism   Lactococcus cremoris strain FM-YL11     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 961088..973235
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J3S98_RS04890 (J3S98_04890) - 961654..962106 (-) 453 WP_015081789.1 hypothetical protein -
  J3S98_RS04895 (J3S98_04895) - 962309..962473 (-) 165 WP_021166195.1 lactococcin family bacteriocin -
  J3S98_RS04900 (J3S98_04900) - 962642..962774 (-) 133 Protein_937 IS3 family transposase -
  J3S98_RS04905 (J3S98_04905) lciB 963254..963529 (-) 276 WP_032488552.1 lactococcin-B immunity protein -
  J3S98_RS04910 (J3S98_04910) - 963556..963762 (-) 207 WP_015081788.1 lactococcin family bacteriocin -
  J3S98_RS04915 (J3S98_04915) - 964037..964333 (-) 297 WP_015081787.1 bacteriocin immunity protein -
  J3S98_RS04920 (J3S98_04920) - 964348..964575 (-) 228 WP_015081786.1 lactococcin family bacteriocin -
  J3S98_RS04925 (J3S98_04925) - 964649..966073 (-) 1425 WP_015081785.1 HlyD family secretion protein -
  J3S98_RS04930 (J3S98_04930) comA 966088..968235 (-) 2148 WP_041931940.1 peptide cleavage/export ABC transporter Regulator
  J3S98_RS04935 (J3S98_04935) - 968651..968899 (-) 249 WP_015081783.1 hypothetical protein -
  J3S98_RS04940 (J3S98_04940) - 969168..971009 (-) 1842 WP_021166190.1 P-loop NTPase fold protein -
  J3S98_RS04945 (J3S98_04945) - 971114..971749 (-) 636 WP_015081781.1 hypothetical protein -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 79810.24 Da        Isoelectric Point: 7.5798

>NTDB_id=547296 J3S98_RS04930 WP_041931940.1 966088..968235(-) (comA) [Lactococcus cremoris strain FM-YL11]
MKFKKKNYTSQVDEMDCGCAALSMILKSYGTEKSLASLRLLAGTTIEGTSALGIKKAAEILEFSVQALRTDASLFEMKNA
PYPFIAHVIKDQKYPHYYVITGANKNSVFIADPDPTIKMTKLSKEAFLSEWTGISLFLSTTPSYHPTKEKASSLLSFIPI
ITRQKKVILNIVIASFIVTLINILGSYYLQSMIDSYIPNALMGTLGIISVGLLLTYIIQQVLEFAKAFLLNVLSQRLAID
VILSYIRHIFQLPMSFFSTRRTGEITSRFSDASSILDAIASTILSLFLDLTIVVMTGLILGLQNMQLFLLVLLAIPLYIV
VIIIFTPLFEKQNHEVMQTNAVLNSSIIEDINGIETIKALASEQERYQKIDYEFASYLKKAFTLQKSEAIQGLIKAIIQL
TLSVTILWFGATLVISQKITLGQLITFNALLSYFTNPITNIINLQTKLQKARVANERLNEVYLVPSEFEEKKTELSLSHF
NLNMSDISYQYGFGRKVLSEIELSIKENEKLTIVGMSGSGKSTLVKLLVNFFQPTSGTITLGGIDLQQFDKHQLRRLINY
LPQQPYIFTGSILDNLLLGANENASQEEILKAVELAEIRADIEQMQLGYQTELSSDASSLSGGQKQRIALARALLSPAKI
LILDEATSNLDMITEKKILKNLLPLDKTIIFIAHRLSVAEMSHRIIVVDQGKVIESGSHVDLLAQNGFYEQLYHN

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=547296 J3S98_RS04930 WP_041931940.1 966088..968235(-) (comA) [Lactococcus cremoris strain FM-YL11]
ATGAAATTTAAAAAGAAAAATTATACCTCACAAGTAGATGAAATGGACTGTGGCTGTGCTGCCTTATCAATGATTTTAAA
GTCTTATGGCACAGAAAAATCTCTCGCTTCATTGCGCTTACTTGCAGGTACAACAATCGAAGGAACCTCCGCTTTAGGGA
TAAAAAAGGCAGCTGAAATATTAGAGTTTTCAGTTCAGGCCCTAAGAACAGATGCAAGCCTTTTTGAAATGAAAAACGCT
CCTTACCCATTTATTGCTCATGTCATTAAAGACCAAAAATACCCACATTATTATGTGATCACTGGCGCAAATAAAAATTC
GGTATTCATTGCTGATCCTGACCCAACCATTAAAATGACAAAATTATCAAAAGAAGCTTTTTTATCGGAATGGACTGGGA
TTAGTTTATTTCTTTCGACTACACCATCTTATCATCCCACTAAAGAAAAAGCTTCCTCATTATTATCTTTTATCCCAATT
ATCACCCGTCAAAAGAAAGTCATTCTCAATATTGTTATTGCCTCATTCATTGTAACACTGATTAATATTCTAGGCTCTTA
CTACCTCCAGAGCATGATTGACAGCTATATTCCAAATGCCTTAATGGGAACTTTAGGGATTATCTCAGTAGGGCTATTGT
TAACCTATATTATCCAACAGGTCTTAGAATTTGCTAAGGCCTTCTTATTGAACGTTCTTTCTCAAAGATTAGCTATTGAT
GTCATTCTTTCTTATATTAGACACATTTTCCAACTTCCCATGTCTTTCTTTTCGACCCGAAGAACAGGAGAAATTACCAG
TCGGTTTTCCGATGCGAGTTCTATTTTAGATGCTATTGCCTCAACGATTCTTTCGCTCTTTTTAGATTTGACGATTGTCG
TCATGACAGGACTAATTTTAGGCCTTCAAAATATGCAACTCTTTCTTCTCGTTCTTTTGGCAATCCCACTCTATATTGTT
GTTATTATTATTTTTACGCCCCTTTTTGAAAAACAAAACCATGAAGTCATGCAGACCAATGCCGTCTTAAACTCCTCAAT
TATTGAAGATATCAATGGGATTGAAACTATAAAGGCACTTGCCAGTGAACAAGAAAGATATCAAAAAATTGACTACGAAT
TTGCAAGTTATCTAAAAAAGGCTTTCACTTTACAAAAATCAGAAGCTATTCAAGGCTTAATTAAAGCAATTATACAACTA
ACATTGAGTGTCACCATTTTATGGTTTGGTGCCACATTAGTAATAAGTCAAAAAATTACGCTCGGACAATTGATTACTTT
TAATGCCCTGCTTTCTTACTTTACAAATCCAATTACCAATATCATTAACCTTCAAACAAAACTACAAAAGGCAAGGGTAG
CCAATGAACGATTAAATGAGGTCTATCTTGTACCCAGTGAATTTGAGGAAAAGAAAACAGAACTGTCCCTCTCACATTTT
AACTTAAACATGTCCGATATTTCATATCAATATGGTTTTGGCAGAAAAGTCTTATCTGAGATAGAACTCTCTATTAAAGA
AAATGAAAAATTGACTATTGTGGGCATGAGTGGTTCAGGAAAGAGTACCCTTGTTAAATTATTGGTCAACTTCTTTCAAC
CCACTTCTGGCACCATCACTTTAGGTGGAATTGACCTGCAACAGTTTGATAAACACCAACTCCGAAGATTAATCAACTAT
CTTCCCCAACAACCTTATATTTTTACTGGTTCAATTTTAGATAATCTACTTCTAGGAGCTAATGAGAATGCATCACAAGA
AGAGATTCTTAAAGCGGTGGAATTGGCAGAAATCCGTGCAGATATTGAACAAATGCAGTTGGGCTATCAGACCGAACTTT
CAAGTGATGCAAGTAGTCTATCGGGGGGACAAAAACAACGCATTGCTTTAGCTCGTGCGCTCCTTTCCCCTGCCAAAATC
CTCATTTTAGATGAAGCAACCAGTAACCTTGATATGATTACAGAGAAGAAAATATTAAAGAACTTGTTGCCCTTGGATAA
AACCATTATTTTCATTGCTCACCGCCTCTCTGTGGCGGAAATGAGTCATCGAATTATTGTTGTCGATCAAGGAAAAGTGA
TAGAGAGTGGCTCACATGTTGACCTGCTTGCACAAAATGGCTTTTATGAACAACTTTACCATAACTGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(6-142)

ABC transporter transmembrane region (ABC_membrane)

(169-437)

ABC transporter (ABC_tran)

(498-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

60.924

99.86

0.608
  comA Streptococcus mitis NCTC 12261

59.944

99.86

0.599
  comA Streptococcus mitis SK321

59.664

99.86

0.596
  comA Streptococcus pneumoniae R6

59.524

99.86

0.594
  comA Streptococcus pneumoniae Rx1

59.524

99.86

0.594
  comA Streptococcus pneumoniae D39

59.524

99.86

0.594
  comA Streptococcus pneumoniae TIGR4

59.244

99.86

0.592
  comA/nlmT Streptococcus mutans UA159

57.799

100

0.58