Detailed information NTG0547072

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: J1N58_RS11690
• Genome accession: NZ_CP071697
• Coordinates: 2437032..2438228 (+)
• Length: 398 a.a.
• NCBI ID: WP_043024644.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 1112S
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	2434123..2439739	2437032..2438228	within	0

Gene organization within MGE regions

Location: 2434123..2439739

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J1N58_RS11670 (J1N58_11670)	-	2434123..2435286 (+)	1164	WP_100881157.1	IS30 family transposase	-
J1N58_RS11680 (J1N58_11680)	-	2435671..2436354 (-)	684	WP_024393106.1	YoaK family protein	-
J1N58_RS11685 (J1N58_11685)	rlmH	2436379..2436858 (-)	480	WP_044764447.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
J1N58_RS11690 (J1N58_11690)	htrA	2437032..2438228 (+)	1197	WP_043024644.1	trypsin-like peptidase domain-containing protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41850.93 Da
• Isoelectric Point: 4.5454

>NTDB_id=547072 J1N58_RS11690 WP_043024644.1 2437032..2438228(+) (htrA) [Streptococcus suis strain 1112S]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGVIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKAGKVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGETIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=547072 J1N58_RS11690 WP_043024644.1 2437032..2438228(+) (htrA) [Streptococcus suis strain 1112S]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATTGG
GGCCTTATCAGCATCTTTCTTCCAACCACAGGTTCAACAAGCAAATTCTGCCATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAATCAGCC
AACAATAGTCTTGGTGTTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCTAATACAGTTACTCAAGGTATTATTTCTAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ATGGTCAAACAATCTCAACCAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGAGGACCATTGATTAAT
ATCCAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCAGGTGTGGCTGTGGAAGG
GATGGGATTTGCTATTCCTGCAAATGATGCCGTAGCCATTATCAATCAACTTGAGAAAGCTGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTGGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTCGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTCATTACTGA
GATTGACGGAGAAACTATTCAAAATAAGAGTGATCTCCAAAGTGCTCTCTACAAACATCAAATCGGAGACACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (293-389)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.453	99.749	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	60.253	99.246	0.598
htrA	Streptococcus pneumoniae D39	57.506	98.744	0.568
htrA	Streptococcus pneumoniae TIGR4	57.506	98.744	0.568
htrA	Streptococcus mitis NCTC 12261	57.506	98.744	0.568
htrA	Streptococcus pneumoniae R6	57.506	98.744	0.568
htrA	Streptococcus pneumoniae Rx1	57.506	98.744	0.568